BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

638 related articles for article (PubMed ID: 15798194)

  • 1. PKR and GCN2 kinases and guanine nucleotide exchange factor eukaryotic translation initiation factor 2B (eIF2B) recognize overlapping surfaces on eIF2alpha.
    Dey M; Trieselmann B; Locke EG; Lu J; Cao C; Dar AC; Krishnamoorthy T; Dong J; Sicheri F; Dever TE
    Mol Cell Biol; 2005 Apr; 25(8):3063-75. PubMed ID: 15798194
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphorylation of translation initiation factor eIF2α at Ser51 depends on site- and context-specific information.
    Uppala JK; Ghosh C; Sathe L; Dey M
    FEBS Lett; 2018 Sep; 592(18):3116-3125. PubMed ID: 30070006
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The double-stranded RNA-activated protein kinase PKR is dispensable for regulation of translation initiation in response to either calcium mobilization from the endoplasmic reticulum or essential amino acid starvation.
    Kimball SR; Clemens MJ; Tilleray VJ; Wek RC; Horetsky RL; Jefferson LS
    Biochem Biophys Res Commun; 2001 Jan; 280(1):293-300. PubMed ID: 11162513
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Functional complementation by wheat eIF2alpha in the yeast GCN2-mediated pathway.
    Chang LY; Yang WY; Roth D
    Biochem Biophys Res Commun; 2000 Dec; 279(2):468-74. PubMed ID: 11118310
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The beta/Gcd7 subunit of eukaryotic translation initiation factor 2B (eIF2B), a guanine nucleotide exchange factor, is crucial for binding eIF2 in vivo.
    Dev K; Qiu H; Dong J; Zhang F; Barthlme D; Hinnebusch AG
    Mol Cell Biol; 2010 Nov; 30(21):5218-33. PubMed ID: 20805354
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of translation initiation by amino acids in eukaryotic cells.
    Kimball SR
    Prog Mol Subcell Biol; 2001; 26():155-84. PubMed ID: 11575165
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nck-1 selectively modulates eIF2alphaSer51 phosphorylation by a subset of eIF2alpha-kinases.
    Cardin E; Latreille M; Khoury C; Greenwood MT; Larose L
    FEBS J; 2007 Nov; 274(22):5865-75. PubMed ID: 17944934
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Residues required for phosphorylation of translation initiation factor eIF2α under diverse stress conditions are divergent between yeast and human.
    Majumder M; Mitchell D; Merkulov S; Wu J; Guan BJ; Snider MD; Krokowski D; Yee VC; Hatzoglou M
    Int J Biochem Cell Biol; 2015 Feb; 59():135-41. PubMed ID: 25541374
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Requirement for kinase-induced conformational change in eukaryotic initiation factor 2alpha (eIF2alpha) restricts phosphorylation of Ser51.
    Dey M; Velyvis A; Li JJ; Chiu E; Chiovitti D; Kay LE; Sicheri F; Dever TE
    Proc Natl Acad Sci U S A; 2011 Mar; 108(11):4316-21. PubMed ID: 21368187
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanistic link between PKR dimerization, autophosphorylation, and eIF2alpha substrate recognition.
    Dey M; Cao C; Dar AC; Tamura T; Ozato K; Sicheri F; Dever TE
    Cell; 2005 Sep; 122(6):901-13. PubMed ID: 16179259
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphorylation of serine 51 in initiation factor 2 alpha (eIF2 alpha) promotes complex formation between eIF2 alpha(P) and eIF2B and causes inhibition in the guanine nucleotide exchange activity of eIF2B.
    Sudhakar A; Ramachandran A; Ghosh S; Hasnain SE; Kaufman RJ; Ramaiah KV
    Biochemistry; 2000 Oct; 39(42):12929-38. PubMed ID: 11041858
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation.
    Krishnamoorthy T; Pavitt GD; Zhang F; Dever TE; Hinnebusch AG
    Mol Cell Biol; 2001 Aug; 21(15):5018-30. PubMed ID: 11438658
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Conserved bipartite motifs in yeast eIF5 and eIF2Bepsilon, GTPase-activating and GDP-GTP exchange factors in translation initiation, mediate binding to their common substrate eIF2.
    Asano K; Krishnamoorthy T; Phan L; Pavitt GD; Hinnebusch AG
    EMBO J; 1999 Mar; 18(6):1673-88. PubMed ID: 10075937
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Autophosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2alpha kinases PKR and GCN2.
    Romano PR; Garcia-Barrio MT; Zhang X; Wang Q; Taylor DR; Zhang F; Herring C; Mathews MB; Qin J; Hinnebusch AG
    Mol Cell Biol; 1998 Apr; 18(4):2282-97. PubMed ID: 9528799
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression and purification of the alpha-subunit of eukaryotic initiation factor eIF2: use as a kinase substrate.
    Kimball SR; Horetsky RL; Jagus R; Jefferson LS
    Protein Expr Purif; 1998 Apr; 12(3):415-9. PubMed ID: 9535710
    [TBL] [Abstract][Full Text] [Related]  

  • 16. eIF2B as a Target for Viral Evasion of PKR-Mediated Translation Inhibition.
    Wuerth JD; Habjan M; Kainulainen M; Berisha B; Bertheloot D; Superti-Furga G; Pichlmair A; Weber F
    mBio; 2020 Jul; 11(4):. PubMed ID: 32665273
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of domains and residues within the epsilon subunit of eukaryotic translation initiation factor 2B (eIF2Bepsilon) required for guanine nucleotide exchange reveals a novel activation function promoted by eIF2B complex formation.
    Gomez E; Pavitt GD
    Mol Cell Biol; 2000 Jun; 20(11):3965-76. PubMed ID: 10805739
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Study of translational control of eukaryotic gene expression using yeast.
    Hinnebusch AG; Asano K; Olsen DS; Phan L; Nielsen KH; Valásek L
    Ann N Y Acad Sci; 2004 Dec; 1038():60-74. PubMed ID: 15838098
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Homologous segments in three subunits of the guanine nucleotide exchange factor eIF2B mediate translational regulation by phosphorylation of eIF2.
    Pavitt GD; Yang W; Hinnebusch AG
    Mol Cell Biol; 1997 Mar; 17(3):1298-313. PubMed ID: 9032257
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutations in the GCD7 subunit of yeast guanine nucleotide exchange factor eIF-2B overcome the inhibitory effects of phosphorylated eIF-2 on translation initiation.
    Vazquez de Aldana CR; Hinnebusch AG
    Mol Cell Biol; 1994 May; 14(5):3208-22. PubMed ID: 8164676
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.