These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

222 related articles for article (PubMed ID: 15798395)

  • 21. Evaluation of functional and binding assays in cells expressing either recombinant or endogenous hERG channel.
    Murphy SM; Palmer M; Poole MF; Padegimas L; Hunady K; Danzig J; Gill S; Gill R; Ting A; Sherf B; Brunden K; Stricker-Krongrad A
    J Pharmacol Toxicol Methods; 2006; 54(1):42-55. PubMed ID: 16326118
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Inactivation gating determines drug potency: a common mechanism for drug blockade of HERG channels.
    Yang BF; Xu DH; Xu CQ; Li Z; Du ZM; Wang HZ; Dong DL
    Acta Pharmacol Sin; 2004 May; 25(5):554-60. PubMed ID: 15132818
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Comparative pharmacology of guinea pig cardiac myocyte and cloned hERG (I(Kr)) channel.
    Davie C; Pierre-Valentin J; Pollard C; Standen N; Mitcheson J; Alexander P; Thong B
    J Cardiovasc Electrophysiol; 2004 Nov; 15(11):1302-9. PubMed ID: 15574182
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Improved throughput of PatchXpress hERG assay using intracellular potassium fluoride.
    Zeng H; Penniman JR; Kinose F; Kim D; Trepakova ES; Malik MG; Dech SJ; Balasubramanian B; Salata JJ
    Assay Drug Dev Technol; 2008 Apr; 6(2):235-41. PubMed ID: 18471077
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Estimation of potency of HERG channel blockers: impact of voltage protocol and temperature.
    Yao JA; Du X; Lu D; Baker RL; Daharsh E; Atterson P
    J Pharmacol Toxicol Methods; 2005; 52(1):146-53. PubMed ID: 15936218
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Analogs of MK-499 are differentially affected by a mutation in the S6 domain of the hERG K+ channel.
    Karczewski J; Wang J; Kane SA; Kiss L; Koblan KS; Culberson JC; Spencer RH
    Biochem Pharmacol; 2009 May; 77(10):1602-11. PubMed ID: 19426697
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The action of a novel fluoroquinolone antibiotic agent antofloxacin hydrochloride on human-ether-à-go-go-related gene potassium channel.
    Guo J; Han SN; Liu JX; Zhang XM; Hu ZS; Shi J; Zhang LR; Zhao ZZ; Zhang Z
    Basic Clin Pharmacol Toxicol; 2010 Aug; 107(2):643-9. PubMed ID: 20662825
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Automated electrophysiology in the preclinical evaluation of drugs for potential QT prolongation.
    Guo L; Guthrie H
    J Pharmacol Toxicol Methods; 2005; 52(1):123-35. PubMed ID: 15936217
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Mechanism of block of hEag1 K+ channels by imipramine and astemizole.
    García-Ferreiro RE; Kerschensteiner D; Major F; Monje F; Stühmer W; Pardo LA
    J Gen Physiol; 2004 Oct; 124(4):301-17. PubMed ID: 15365094
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Propranolol inhibits the human ether-a-go-go-related gene potassium channels.
    Yao X; McIntyre MS; Lang DG; Song IH; Becherer JD; Hashim MA
    Eur J Pharmacol; 2005 Sep; 519(3):208-11. PubMed ID: 16150441
    [TBL] [Abstract][Full Text] [Related]  

  • 31. A benchmark study with sealchip planar patch-clamp technology.
    Xu J; Guia A; Rothwarf D; Huang M; Sithiphong K; Ouang J; Tao G; Wang X; Wu L
    Assay Drug Dev Technol; 2003 Oct; 1(5):675-84. PubMed ID: 15090240
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Assessing hERG channel inhibition using PatchXpress.
    Ly JQ; Shyy G; Misner DL
    Clin Lab Med; 2007 Mar; 27(1):201-8. PubMed ID: 17416313
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Protein binding-dependent decreases in hERG channel blocker potency assessed by whole-cell voltage clamp in serum.
    Margulis M; Sorota S; Chu I; Soares A; Priestley T; Nomeir AA
    J Cardiovasc Pharmacol; 2010 Apr; 55(4):368-76. PubMed ID: 20125032
    [TBL] [Abstract][Full Text] [Related]  

  • 34. High-throughput screening for Kv1.3 channel blockers using an improved FLIPR-based membrane-potential assay.
    Liu K; Samuel M; Tillett J; Hennan JK; Mekonnen B; Soloveva V; Harrison RK; Paslay JW; Larocque J
    J Biomol Screen; 2010 Feb; 15(2):185-95. PubMed ID: 20044579
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Flunarizine is a highly potent inhibitor of cardiac hERG potassium current.
    Trepakova ES; Dech SJ; Salata JJ
    J Cardiovasc Pharmacol; 2006 Feb; 47(2):211-20. PubMed ID: 16495758
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Support vector machines classification of hERG liabilities based on atom types.
    Jia L; Sun H
    Bioorg Med Chem; 2008 Jun; 16(11):6252-60. PubMed ID: 18448342
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Effects of irbesartan on cloned potassium channels involved in human cardiac repolarization.
    Moreno I; Caballero R; González T; Arias C; Valenzuela C; Iriepa I; Gálvez E; Tamargo J; Delpón E
    J Pharmacol Exp Ther; 2003 Feb; 304(2):862-73. PubMed ID: 12538844
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Human embryonic stem cell derived cardiac myocytes detect hERG-mediated repolarization effects, but not Nav1.5 induced depolarization delay.
    Qu Y; Gao B; Fang M; Vargas HM
    J Pharmacol Toxicol Methods; 2013; 68(1):74-81. PubMed ID: 23518063
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Variability in the measurement of hERG potassium channel inhibition: effects of temperature and stimulus pattern.
    Kirsch GE; Trepakova ES; Brimecombe JC; Sidach SS; Erickson HD; Kochan MC; Shyjka LM; Lacerda AE; Brown AM
    J Pharmacol Toxicol Methods; 2004; 50(2):93-101. PubMed ID: 15385083
    [TBL] [Abstract][Full Text] [Related]  

  • 40. High quality ion channel analysis on a chip with the NPC technology.
    Brüggemann A; George M; Klau M; Beckler M; Steindl J; Behrends JC; Fertig N
    Assay Drug Dev Technol; 2003 Oct; 1(5):665-73. PubMed ID: 15090239
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.