Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

113 related articles for article (PubMed ID: 15799689)

  • 1. Effects of N1, N13-diethylnorspermine (DENSPM) and X-radiation treatment on human colorectal tumor clones with varying X-radiation and drug responses.
    Qutob SS; Proulx D; Mesak FM; Ng CE
    Radiat Res; 2005 Apr; 163(4):357-63. PubMed ID: 15799689
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The role of spermidine/spermine N1-acetyltransferase in determining response to chemotherapeutic agents in colorectal cancer cells.
    Allen WL; McLean EG; Boyer J; McCulla A; Wilson PM; Coyle V; Longley DB; Casero RA; Johnston PG
    Mol Cancer Ther; 2007 Jan; 6(1):128-37. PubMed ID: 17237273
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Combination effects of platinum drugs and N1, N11 diethylnorspermine on spermidine/spermine N1-acetyltransferase, polyamines and growth inhibition in A2780 human ovarian carcinoma cells and their oxaliplatin and cisplatin-resistant variants.
    Tummala R; Diegelman P; Hector S; Kramer DL; Clark K; Zagst P; Fetterly G; Porter CW; Pendyala L
    Cancer Chemother Pharmacol; 2011 Feb; 67(2):401-14. PubMed ID: 20443003
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Polyamine catabolism in platinum drug action: Interactions between oxaliplatin and the polyamine analogue N1,N11-diethylnorspermine at the level of spermidine/spermine N1-acetyltransferase.
    Hector S; Porter CW; Kramer DL; Clark K; Prey J; Kisiel N; Diegelman P; Chen Y; Pendyala L
    Mol Cancer Ther; 2004 Jul; 3(7):813-22. PubMed ID: 15252142
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparison of the X-radiation, drug and ultraviolet-radiation responses of clones isolated from a human colorectal tumor cell line.
    Qutob SS; Multani AS; Pathak S; Feng Y; Kendal WS; Ng CE
    Radiat Res; 2004 Mar; 161(3):326-34. PubMed ID: 14982481
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transgenic mice with activated polyamine catabolism due to overexpression of spermidine/spermine N1-acetyltransferase show enhanced sensitivity to the polyamine analog, N1, N11-diethylnorspermine.
    Alhonen L; Pietilä M; Halmekytö M; Kramer DL; Jänne J; Porter CW
    Mol Pharmacol; 1999 Apr; 55(4):693-8. PubMed ID: 10101027
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Polyamine catabolism in colorectal cancer cells following treatment with oxaliplatin, 5-fluorouracil and N1, N11 diethylnorspermine.
    Hector S; Tummala R; Kisiel ND; Diegelman P; Vujcic S; Clark K; Fakih M; Kramer DL; Porter CW; Pendyala L
    Cancer Chemother Pharmacol; 2008 Aug; 62(3):517-27. PubMed ID: 17987291
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Preclinical antitumor efficacy of the polyamine analogue N1, N11-diethylnorspermine administered by multiple injection or continuous infusion.
    Bernacki RJ; Oberman EJ; Seweryniak KE; Atwood A; Bergeron RJ; Porter CW
    Clin Cancer Res; 1995 Aug; 1(8):847-57. PubMed ID: 9816054
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Induction of spermidine/spermine N1-acetyltransferase in breast cancer tissues treated with the polyamine analogue N1, N11-diethylnorspermine.
    Gabrielson E; Tully E; Hacker A; Pegg AE; Davidson NE; Casero RA
    Cancer Chemother Pharmacol; 2004 Aug; 54(2):122-6. PubMed ID: 15138709
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Overexpression of SSAT by DENSPM treatment induces cell detachment and apoptosis in glioblastoma.
    Tian Y; Wang S; Wang B; Zhang J; Jiang R; Zhang W
    Oncol Rep; 2012 Apr; 27(4):1227-32. PubMed ID: 22179681
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Correlation of polyamine and growth responses to N1,N11-diethylnorspermine in primary fetal fibroblasts derived from transgenic mice overexpressing spermidine/spermine N1-acetyltransferase.
    Alhonen L; Karppinen A; Uusi-Oukari M; Vujcic S; Korhonen VP; Halmekytö M; Kramer DL; Hines R; Jänne J; Porter CW
    J Biol Chem; 1998 Jan; 273(4):1964-9. PubMed ID: 9442032
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Collateral sensitivity of human melanoma multidrug-resistant variants to the polyamine analogue, N1,N11-diethylnorspermine.
    Porter CW; Ganis B; Rustum Y; Wrzosek C; Kramer DL; Bergeron RJ
    Cancer Res; 1994 Nov; 54(22):5917-24. PubMed ID: 7954423
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The polyamine analogue N1,N11-diethylnorspermine can induce chondrocyte apoptosis independently of its ability to alter metabolism and levels of natural polyamines.
    Stanic' I; Facchini A; Borzì RM; Stefanelli C; Flamigni F
    J Cell Physiol; 2009 Apr; 219(1):109-16. PubMed ID: 19097065
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Combination of 5-fluorouracil and N1,N11-diethylnorspermine markedly activates spermidine/spermine N1-acetyltransferase expression, depletes polyamines, and synergistically induces apoptosis in colon carcinoma cells.
    Choi W; Gerner EW; Ramdas L; Dupart J; Carew J; Proctor L; Huang P; Zhang W; Hamilton SR
    J Biol Chem; 2005 Feb; 280(5):3295-304. PubMed ID: 15546879
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mice with targeted disruption of spermidine/spermine N1-acetyltransferase gene maintain nearly normal tissue polyamine homeostasis but show signs of insulin resistance upon aging.
    Niiranen K; Keinänen TA; Pirinen E; Heikkinen S; Tusa M; Fatrai S; Suppola S; Pietilä M; Uimari A; Laakso M; Alhonen L; Jänne J
    J Cell Mol Med; 2006; 10(4):933-45. PubMed ID: 17125596
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Small interfering RNA suppression of polyamine analog-induced spermidine/spermine n1-acetyltransferase.
    Chen Y; Kramer DL; Jell J; Vujcic S; Porter CW
    Mol Pharmacol; 2003 Nov; 64(5):1153-9. PubMed ID: 14573765
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of autophagy enhances DENSpm-induced apoptosis in human colon cancer cells in a p53 independent manner.
    Gurkan AC; Arisan ED; Yerlikaya PO; Ilhan H; Unsal NP
    Cell Oncol (Dordr); 2018 Jun; 41(3):297-317. PubMed ID: 29492901
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antitumor activity of the polyamine analog N(1), N(11)-diethylnorspermine against human prostate carcinoma cells.
    Schipper RG; Deli G; Deloyer P; Lange WP; Schalken JA; Verhofstad AA
    Prostate; 2000 Sep; 44(4):313-21. PubMed ID: 10951496
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Loss of inhibitor of apoptosis proteins as a determinant of polyamine analog-induced apoptosis in human melanoma cells.
    Chen Y; Kramer DL; Li F; Porter CW
    Oncogene; 2003 Aug; 22(32):4964-72. PubMed ID: 12902979
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DENSpm overcame Bcl-2 mediated resistance against Paclitaxel treatment in MCF-7 breast cancer cells via activating polyamine catabolic machinery.
    Akyol Z; Çoker-Gürkan A; Arisan ED; Obakan-Yerlikaya P; Palavan-Ünsal N
    Biomed Pharmacother; 2016 Dec; 84():2029-2041. PubMed ID: 27881234
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.