363 related articles for article (PubMed ID: 15799715)
1. Electrostatic stabilization in a pre-organized polar active site: the catalytic role of Lys-80 in Candida tenuis xylose reductase (AKR2B5) probed by site-directed mutagenesis and functional complementation studies.
Kratzer R; Nidetzky B
Biochem J; 2005 Jul; 389(Pt 2):507-15. PubMed ID: 15799715
[TBL] [Abstract][Full Text] [Related]
2. The catalytic mechanism of NADH-dependent reduction of 9,10-phenanthrenequinone by Candida tenuis xylose reductase reveals plasticity in an aldo-keto reductase active site.
Pival SL; Klimacek M; Nidetzky B
Biochem J; 2009 Jun; 421(1):43-9. PubMed ID: 19368528
[TBL] [Abstract][Full Text] [Related]
3. Studies of the enzymic mechanism of Candida tenuis xylose reductase (AKR 2B5): X-ray structure and catalytic reaction profile for the H113A mutant.
Kratzer R; Kavanagh KL; Wilson DK; Nidetzky B
Biochemistry; 2004 May; 43(17):4944-54. PubMed ID: 15109252
[TBL] [Abstract][Full Text] [Related]
4. The coenzyme specificity of Candida tenuis xylose reductase (AKR2B5) explored by site-directed mutagenesis and X-ray crystallography.
Petschacher B; Leitgeb S; Kavanagh KL; Wilson DK; Nidetzky B
Biochem J; 2005 Jan; 385(Pt 1):75-83. PubMed ID: 15320875
[TBL] [Abstract][Full Text] [Related]
5. Tyr-51 is the proton donor-acceptor for NAD(H)-dependent interconversion of xylose and xylitol by Candida tenuis xylose reductase (AKR2B5).
Pival SL; Klimacek M; Kratzer R; Nidetzky B
FEBS Lett; 2008 Dec; 582(29):4095-9. PubMed ID: 19026644
[TBL] [Abstract][Full Text] [Related]
6. Probing the substrate binding site of Candida tenuis xylose reductase (AKR2B5) with site-directed mutagenesis.
Kratzer R; Leitgeb S; Wilson DK; Nidetzky B
Biochem J; 2006 Jan; 393(Pt 1):51-8. PubMed ID: 16336198
[TBL] [Abstract][Full Text] [Related]
7. Multiple forms of xylose reductase in Candida intermedia: comparison of their functional properties using quantitative structure-activity relationships, steady-state kinetic analysis, and pH studies.
Nidetzky B; Brüggler K; Kratzer R; Mayr P
J Agric Food Chem; 2003 Dec; 51(27):7930-5. PubMed ID: 14690376
[TBL] [Abstract][Full Text] [Related]
8. Transient-state and steady-state kinetic studies of the mechanism of NADH-dependent aldehyde reduction catalyzed by xylose reductase from the yeast Candida tenuis.
Nidetzky B; Klimacek M; Mayr P
Biochemistry; 2001 Aug; 40(34):10371-81. PubMed ID: 11513616
[TBL] [Abstract][Full Text] [Related]
9. Catalytic mechanism and substrate selectivity of aldo-keto reductases: insights from structure-function studies of Candida tenuis xylose reductase.
Kratzer R; Wilson DK; Nidetzky B
IUBMB Life; 2006 Sep; 58(9):499-507. PubMed ID: 17002977
[TBL] [Abstract][Full Text] [Related]
10. Catalytic reaction profile for NADH-dependent reduction of aromatic aldehydes by xylose reductase from Candida tenuis.
Mayr P; Nidetzky B
Biochem J; 2002 Sep; 366(Pt 3):889-99. PubMed ID: 12003638
[TBL] [Abstract][Full Text] [Related]
11. Retention of NADPH-linked quinone reductase activity in an aldo-keto reductase following mutation of the catalytic tyrosine.
Schlegel BP; Ratnam K; Penning TM
Biochemistry; 1998 Aug; 37(31):11003-11. PubMed ID: 9692994
[TBL] [Abstract][Full Text] [Related]
12. Fine tuning of coenzyme specificity in family 2 aldo-keto reductases revealed by crystal structures of the Lys-274-->Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD+ and NADP+.
Leitgeb S; Petschacher B; Wilson DK; Nidetzky B
FEBS Lett; 2005 Jan; 579(3):763-7. PubMed ID: 15670843
[TBL] [Abstract][Full Text] [Related]
13. Structure of xylose reductase bound to NAD+ and the basis for single and dual co-substrate specificity in family 2 aldo-keto reductases.
Kavanagh KL; Klimacek M; Nidetzky B; Wilson DK
Biochem J; 2003 Jul; 373(Pt 2):319-26. PubMed ID: 12733986
[TBL] [Abstract][Full Text] [Related]
14. Engineering of a matched pair of xylose reductase and xylitol dehydrogenase for xylose fermentation by Saccharomyces cerevisiae.
Krahulec S; Klimacek M; Nidetzky B
Biotechnol J; 2009 May; 4(5):684-94. PubMed ID: 19452479
[TBL] [Abstract][Full Text] [Related]
15. Mutagenesis of 3 alpha-hydroxysteroid dehydrogenase reveals a "push-pull" mechanism for proton transfer in aldo-keto reductases.
Schlegel BP; Jez JM; Penning TM
Biochemistry; 1998 Mar; 37(10):3538-48. PubMed ID: 9521675
[TBL] [Abstract][Full Text] [Related]
16. Binding energy and specificity in the catalytic mechanism of yeast aldose reductases.
Nidetzky B; Mayr P; Hadwiger P; Stütz AE
Biochem J; 1999 Nov; 344 Pt 1(Pt 1):101-7. PubMed ID: 10548539
[TBL] [Abstract][Full Text] [Related]
17. Exploring the active site of yeast xylose reductase by site-directed mutagenesis of sequence motifs characteristic of two dehydrogenase/reductase family types.
Klimacek M; Szekely M; Griessler R; Nidetzky B
FEBS Lett; 2001 Jul; 500(3):149-52. PubMed ID: 11445075
[TBL] [Abstract][Full Text] [Related]
18. Engineering Candida tenuis Xylose reductase for improved utilization of NADH: antagonistic effects of multiple side chain replacements and performance of site-directed mutants under simulated in vivo conditions.
Petschacher B; Nidetzky B
Appl Environ Microbiol; 2005 Oct; 71(10):6390-3. PubMed ID: 16204564
[TBL] [Abstract][Full Text] [Related]
19. On the role of Brønsted catalysis in Pseudomonas fluorescens mannitol 2-dehydrogenase.
Klimacek M; Kavanagh KL; Wilson DK; Nidetzky B
Biochem J; 2003 Oct; 375(Pt 1):141-9. PubMed ID: 12826012
[TBL] [Abstract][Full Text] [Related]
20. Altering dimer contacts in xylose reductase from Candida tenuis by site-directed mutagenesis: structural and functional properties of R180A mutant.
Klimacek M; Wührer F; Kavanagh KL; Wilson DK; Nidetzky B
Chem Biol Interact; 2003 Feb; 143-144():523-32. PubMed ID: 12604238
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]