BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

261 related articles for article (PubMed ID: 15805253)

  • 1. p53 mutations in benzo(a)pyrene-exposed human p53 knock-in murine fibroblasts correlate with p53 mutations in human lung tumors.
    Liu Z; Muehlbauer KR; Schmeiser HH; Hergenhahn M; Belharazem D; Hollstein MC
    Cancer Res; 2005 Apr; 65(7):2583-7. PubMed ID: 15805253
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutability of p53 hotspot codons to benzo(a)pyrene diol epoxide (BPDE) and the frequency of p53 mutations in nontumorous human lung.
    Hussain SP; Amstad P; Raja K; Sawyer M; Hofseth L; Shields PG; Hewer A; Phillips DH; Ryberg D; Haugen A; Harris CC
    Cancer Res; 2001 Sep; 61(17):6350-5. PubMed ID: 11522624
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Methylated CpG dinucleotides are the preferential targets for G-to-T transversion mutations induced by benzo[a]pyrene diol epoxide in mammalian cells: similarities with the p53 mutation spectrum in smoking-associated lung cancers.
    Yoon JH; Smith LE; Feng Z; Tang M; Lee CS; Pfeifer GP
    Cancer Res; 2001 Oct; 61(19):7110-7. PubMed ID: 11585742
    [TBL] [Abstract][Full Text] [Related]  

  • 4. p53 gene mutations in SKH-1 mouse tumors differentially induced by UVB and combined subcarcinogenic benzo[a]pyrene and UVA.
    Wang Y; Zhou X; Weinstein E; Maryles B; Zhang Y; Moore J; Gao D; Atencio DP; Rosenstein BS; Lebwohl M; Chen HD; Xiao T; Wei H
    Photochem Photobiol; 2008; 84(2):444-9. PubMed ID: 18248503
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human tumor p53 mutations are selected for in mouse embryonic fibroblasts harboring a humanized p53 gene.
    Liu Z; Hergenhahn M; Schmeiser HH; Wogan GN; Hong A; Hollstein M
    Proc Natl Acad Sci U S A; 2004 Mar; 101(9):2963-8. PubMed ID: 14976251
    [TBL] [Abstract][Full Text] [Related]  

  • 6. UV-induced DNA damage and mutations in Hupki (human p53 knock-in) mice recapitulate p53 hotspot alterations in sun-exposed human skin.
    Luo JL; Tong WM; Yoon JH; Hergenhahn M; Koomagi R; Yang Q; Galendo D; Pfeifer GP; Wang ZQ; Hollstein M
    Cancer Res; 2001 Nov; 61(22):8158-63. PubMed ID: 11719445
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA adduct measurements, cell proliferation and tumor mutation induction in relation to tumor formation in B6C3F1 mice fed coal tar or benzo[a]pyrene.
    Culp SJ; Warbritton AR; Smith BA; Li EE; Beland FA
    Carcinogenesis; 2000 Jul; 21(7):1433-40. PubMed ID: 10874023
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts.
    Kucab JE; van Steeg H; Luijten M; Schmeiser HH; White PA; Phillips DH; Arlt VM
    Mutat Res; 2015 Mar; 773():48-62. PubMed ID: 25847421
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mice with alterations in both p53 and Ink4a/Arf display a striking increase in lung tumor multiplicity and progression: differential chemopreventive effect of budesonide in wild-type and mutant A/J mice.
    Wang Y; Zhang Z; Kastens E; Lubet RA; You M
    Cancer Res; 2003 Aug; 63(15):4389-95. PubMed ID: 12907609
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular alterations and lung tumors in p53 mutant mice exposed to cigarette smoke.
    De Flora S; Balansky RM; D'Agostini F; Izzotti A; Camoirano A; Bennicelli C; Zhang Z; Wang Y; Lubet RA; You M
    Cancer Res; 2003 Feb; 63(4):793-800. PubMed ID: 12591728
    [TBL] [Abstract][Full Text] [Related]  

  • 11. p53 and K-ras mutations in lung cancers from former and never-smoking women.
    Vähäkangas KH; Bennett WP; Castrén K; Welsh JA; Khan MA; Blömeke B; Alavanja MC; Harris CC
    Cancer Res; 2001 Jun; 61(11):4350-6. PubMed ID: 11389059
    [TBL] [Abstract][Full Text] [Related]  

  • 12. p53 mutations in lung cancer following radiation therapy for Hodgkin's disease.
    De Benedetti VM; Travis LB; Welsh JA; van Leeuwen FE; Stovall M; Clarke EA; Boice JD; Bennett WP
    Cancer Epidemiol Biomarkers Prev; 1996 Feb; 5(2):93-8. PubMed ID: 8850268
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Mutations of tumor suppressor gemne TP53 in tobacco smoke-associated tumors].
    Szyfter K; Kiwerska K; Rydzanicz M; Kruszyna Ł; Zemleduch T; Jagodziński P
    Przegl Lek; 2009; 66(10):603-7. PubMed ID: 20301891
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutational signature of the proximate bladder carcinogen N-hydroxy-4-acetylaminobiphenyl: inconsistency with the p53 mutational spectrum in bladder cancer.
    Besaratinia A; Bates SE; Pfeifer GP
    Cancer Res; 2002 Aug; 62(15):4331-8. PubMed ID: 12154037
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Distinct pattern of p53 mutations in bladder cancer: relationship to tobacco usage.
    Spruck CH; Rideout WM; Olumi AF; Ohneseit PF; Yang AS; Tsai YC; Nichols PW; Horn T; Hermann GG; Steven K
    Cancer Res; 1993 Mar; 53(5):1162-6. PubMed ID: 8439962
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Selective targeting of p53 gene mutational hotspots in human cancers by etiologically defined carcinogens.
    Puisieux A; Lim S; Groopman J; Ozturk M
    Cancer Res; 1991 Nov; 51(22):6185-9. PubMed ID: 1933877
    [TBL] [Abstract][Full Text] [Related]  

  • 17. K-ras mutations in lung tumors from p53 mutant mice exposed to cigarette smoke.
    Yao R; Wang Y; D'Agostini F; Izzotti A; Lubet RA; You M; De Flora S
    Exp Lung Res; 2005 Mar; 31(2):271-81. PubMed ID: 15824025
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TP53 and KRAS mutation load and types in lung cancers in relation to tobacco smoke: distinct patterns in never, former, and current smokers.
    Le Calvez F; Mukeria A; Hunt JD; Kelm O; Hung RJ; Tanière P; Brennan P; Boffetta P; Zaridze DG; Hainaut P
    Cancer Res; 2005 Jun; 65(12):5076-83. PubMed ID: 15958551
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effect of heterozygous loss of p53 on benzo[a]pyrene-induced mutations and tumors in DNA repair-deficient XPA mice.
    van Oostrom CT; Boeve M; van Den Berg J; de Vries A; Dollé ME; Beems RB; van Kreijl CF; Vijg J; van Steeg H
    Environ Mol Mutagen; 1999; 34(2-3):124-30. PubMed ID: 10529736
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In silico p53 mutation hotspots in lung cancer.
    Lewis PD; Parry JM
    Carcinogenesis; 2004 Jul; 25(7):1099-107. PubMed ID: 14729588
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.