BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

244 related articles for article (PubMed ID: 15805261)

  • 1. Environmental pollutant and potent mutagen 3-nitrobenzanthrone forms DNA adducts after reduction by NAD(P)H:quinone oxidoreductase and conjugation by acetyltransferases and sulfotransferases in human hepatic cytosols.
    Arlt VM; Stiborova M; Henderson CJ; Osborne MR; Bieler CA; Frei E; Martinek V; Sopko B; Wolf CR; Schmeiser HH; Phillips DH
    Cancer Res; 2005 Apr; 65(7):2644-52. PubMed ID: 15805261
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human enzymes involved in the metabolic activation of the environmental contaminant 3-nitrobenzanthrone: evidence for reductive activation by human NADPH:cytochrome p450 reductase.
    Arlt VM; Stiborova M; Hewer A; Schmeiser HH; Phillips DH
    Cancer Res; 2003 Jun; 63(11):2752-61. PubMed ID: 12782579
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The environmental pollutant and carcinogen 3-nitrobenzanthrone induces cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase in rat lung and kidney, thereby enhancing its own genotoxicity.
    Stiborová M; Dracínská H; Mizerovská J; Frei E; Schmeiser HH; Hudecek J; Hodek P; Phillips DH; Arlt VM
    Toxicology; 2008 May; 247(1):11-22. PubMed ID: 18329153
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of 3-nitrobenzanthrone and its metabolites by human acetyltransferases, sulfotransferases and cytochrome P450 expressed in Chinese hamster V79 cells.
    Arlt VM; Glatt H; Muckel E; Pabel U; Sorg BL; Seidel A; Frank H; Schmeiser HH; Phillips DH
    Int J Cancer; 2003 Jul; 105(5):583-92. PubMed ID: 12740904
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The environmental pollutant and carcinogen 3-nitrobenzanthrone and its human metabolite 3-aminobenzanthrone are potent inducers of rat hepatic cytochromes P450 1A1 and -1A2 and NAD(P)H:quinone oxidoreductase.
    Stiborová M; Dracínská H; Hájková J; Kaderábková P; Frei E; Schmeiser HH; Soucek P; Phillips DH; Arlt VM
    Drug Metab Dispos; 2006 Aug; 34(8):1398-405. PubMed ID: 16714372
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanisms of the different DNA adduct forming potentials of the urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone.
    Stiborová M; Martínek V; Svobodová M; Sístková J; Dvorák Z; Ulrichová J; Simánek V; Frei E; Schmeiser HH; Phillips DH; Arlt VM
    Chem Res Toxicol; 2010 Jul; 23(7):1192-201. PubMed ID: 20545351
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolic activation of the environmental contaminant 3-nitrobenzanthrone by human acetyltransferases and sulfotransferase.
    Arlt VM; Glatt H; Muckel E; Pabel U; Sorg BL; Schmeiser HH; Phillips DH
    Carcinogenesis; 2002 Nov; 23(11):1937-45. PubMed ID: 12419844
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Induction of biotransformation enzymes by the carcinogenic air-pollutant 3-nitrobenzanthrone in liver, kidney and lung, after intra-tracheal instillation in rats.
    Mizerovská J; Dračínská H; Frei E; Schmeiser HH; Arlt VM; Stiborová M
    Mutat Res; 2011 Feb; 720(1-2):34-41. PubMed ID: 21167309
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular mechanism of genotoxicity of the environmental pollutant 3-nitrobenzanthrone.
    Stiborová M; Arlt VM; Henderson CJ; Wolf CR; Frei E; Schmeiser HH; Phillips DH
    Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub; 2005 Dec; 149(2):191-7. PubMed ID: 16601755
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparison of activation of aristolochic acid I and II with NADPH:quinone oxidoreductase, sulphotransferases and N-acetyltranferases.
    Martinek V; Kubickova B; Arlt VM; Frei E; Schmeiser HH; Hudecek J; Stiborova M
    Neuro Endocrinol Lett; 2011; 32 Suppl 1():57-70. PubMed ID: 22167209
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone, forms DNA adducts after metabolic activation by human and rat liver microsomes: evidence for activation by cytochrome P450 1A1 and P450 1A2.
    Arlt VM; Hewer A; Sorg BL; Schmeiser HH; Phillips DH; Stiborova M
    Chem Res Toxicol; 2004 Aug; 17(8):1092-101. PubMed ID: 15310241
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of three major DNA adducts formed by the carcinogenic air pollutant 3-nitrobenzanthrone in rat lung at the C8 and N2 position of guanine and at the N6 position of adenine.
    Arlt VM; Schmeiser HH; Osborne MR; Kawanishi M; Kanno T; Yagi T; Phillips DH; Takamura-Enya T
    Int J Cancer; 2006 May; 118(9):2139-46. PubMed ID: 16331602
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 3-aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone, induces biotransformation enzymes in rat kidney and lung.
    Stiborová M; Dracínská H; Martínková M; Mizerovská J; Hudecek J; Hodek P; Liberda J; Frei E; Schmeiser HH; Phillips DH; Arlt VM
    Mutat Res; 2009 May; 676(1-2):93-101. PubMed ID: 19398038
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bioactivation of 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone: evidence for DNA adduct formation mediated by cytochrome P450 enzymes and peroxidases.
    Arlt VM; Henderson CJ; Wolf CR; Schmeiser HH; Phillips DH; Stiborova M
    Cancer Lett; 2006 Mar; 234(2):220-31. PubMed ID: 15885895
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activation and detoxification metabolism of urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone by rat and mouse hepatic microsomes.
    Stiborova M; Cechova T; Borek-Dohalska L; Moserova M; Frei E; Schmeiser HH; Paca J; Arlt VM
    Neuro Endocrinol Lett; 2012; 33 Suppl 3():8-15. PubMed ID: 23353838
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The human carcinogen aristolochic acid i is activated to form DNA adducts by human NAD(P)H:quinone oxidoreductase without the contribution of acetyltransferases or sulfotransferases.
    Stiborová M; Mareš J; Frei E; Arlt VM; Martínek V; Schmeiser HH
    Environ Mol Mutagen; 2011 Jul; 52(6):448-59. PubMed ID: 21370283
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase.
    Stiborová M; Frei E; Sopko B; Sopková K; Marková V; Lanková M; Kumstýrová T; Wiessler M; Schmeiser HH
    Carcinogenesis; 2003 Oct; 24(10):1695-703. PubMed ID: 12869422
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mechanisms of enzyme-catalyzed reduction of two carcinogenic nitro-aromatics, 3-nitrobenzanthrone and aristolochic acid I: Experimental and theoretical approaches.
    Stiborová M; Frei E; Schmeiser HH; Arlt VM; Martínek V
    Int J Mol Sci; 2014 Jun; 15(6):10271-95. PubMed ID: 24918288
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DNA adduct formation by the ubiquitous environmental contaminant 3-nitrobenzanthrone in rats determined by (32)P-postlabeling.
    Arlt VM; Bieler CA; Mier W; Wiessler M; Schmeiser HH
    Int J Cancer; 2001 Aug; 93(3):450-4. PubMed ID: 11433414
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA adducts and mutagenic specificity of the ubiquitous environmental pollutant 3-nitrobenzanthrone in Muta Mouse.
    Arlt VM; Zhan L; Schmeiser HH; Honma M; Hayashi M; Phillips DH; Suzuki T
    Environ Mol Mutagen; 2004; 43(3):186-95. PubMed ID: 15065206
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.