BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

268 related articles for article (PubMed ID: 15806173)

  • 1. Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells.
    Wang HQ; Altomare DA; Skele KL; Poulikakos PI; Kuhajda FP; Di Cristofano A; Testa JR
    Oncogene; 2005 May; 24(22):3574-82. PubMed ID: 15806173
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of the phosphatidylinositol 3'-kinase/PTEN/Akt kinase pathway in the overexpression of fatty acid synthase in LNCaP prostate cancer cells.
    Van de Sande T; De Schrijver E; Heyns W; Verhoeven G; Swinnen JV
    Cancer Res; 2002 Feb; 62(3):642-6. PubMed ID: 11830512
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Akt regulates COX-2 mRNA and protein expression in mutated-PTEN human endometrial cancer cells.
    St-Germain ME; Gagnon V; Mathieu I; Parent S; Asselin E
    Int J Oncol; 2004 May; 24(5):1311-24. PubMed ID: 15067356
    [TBL] [Abstract][Full Text] [Related]  

  • 4. AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth.
    Altomare DA; Wang HQ; Skele KL; De Rienzo A; Klein-Szanto AJ; Godwin AK; Testa JR
    Oncogene; 2004 Jul; 23(34):5853-7. PubMed ID: 15208673
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer.
    Yuan ZQ; Sun M; Feldman RI; Wang G; Ma X; Jiang C; Coppola D; Nicosia SV; Cheng JQ
    Oncogene; 2000 May; 19(19):2324-30. PubMed ID: 10822383
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line.
    Lee S; Choi EJ; Jin C; Kim DH
    Gynecol Oncol; 2005 Apr; 97(1):26-34. PubMed ID: 15790433
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Blockade of fatty acid synthase induces ubiquitination and degradation of phosphoinositide-3-kinase signaling proteins in ovarian cancer.
    Tomek K; Wagner R; Varga F; Singer CF; Karlic H; Grunt TW
    Mol Cancer Res; 2011 Dec; 9(12):1767-79. PubMed ID: 21970855
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacological inhibition of fatty acid synthase (FAS): a novel therapeutic approach for breast cancer chemoprevention through its ability to suppress Her-2/neu (erbB-2) oncogene-induced malignant transformation.
    Menendez JA; Mehmi I; Verma VA; Teng PK; Lupu R
    Mol Carcinog; 2004 Nov; 41(3):164-78. PubMed ID: 15390078
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis, and delays tumor growth.
    Edwards LA; Thiessen B; Dragowska WH; Daynard T; Bally MB; Dedhar S
    Oncogene; 2005 May; 24(22):3596-605. PubMed ID: 15782140
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pharmacological and small interference RNA-mediated inhibition of breast cancer-associated fatty acid synthase (oncogenic antigen-519) synergistically enhances Taxol (paclitaxel)-induced cytotoxicity.
    Menendez JA; Vellon L; Colomer R; Lupu R
    Int J Cancer; 2005 May; 115(1):19-35. PubMed ID: 15657900
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Fatty acid synthase inhibitors cerulenin and C75 retard growth and induce caspase-dependent apoptosis in human melanoma A-375 cells.
    Ho TS; Ho YP; Wong WY; Chi-Ming Chiu L; Wong YS; Eng-Choon Ooi V
    Biomed Pharmacother; 2007 Oct; 61(9):578-87. PubMed ID: 17904792
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphoinositide 3-kinase/Akt involvement in arsenic trioxide resistance of human leukemia cells.
    Tabellini G; Cappellini A; Tazzari PL; FalĂ  F; Billi AM; Manzoli L; Cocco L; Martelli AM
    J Cell Physiol; 2005 Feb; 202(2):623-34. PubMed ID: 15316930
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Preferential killing of PTEN-null myelomas by PI3K inhibitors through Akt pathway.
    Zhang J; Choi Y; Mavromatis B; Lichtenstein A; Li W
    Oncogene; 2003 Sep; 22(40):6289-95. PubMed ID: 13679867
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cell cycle progression and activation of Akt kinase are required for insulin-like growth factor I-mediated suppression of apoptosis in granulosa cells.
    Hu CL; Cowan RG; Harman RM; Quirk SM
    Mol Endocrinol; 2004 Feb; 18(2):326-38. PubMed ID: 14593075
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells.
    Martelli AM; Tazzari PL; Tabellini G; Bortul R; Billi AM; Manzoli L; Ruggeri A; Conte R; Cocco L
    Leukemia; 2003 Sep; 17(9):1794-805. PubMed ID: 12970779
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Correlation between loss of PTEN expression and Akt phosphorylation in endometrial carcinoma.
    Kanamori Y; Kigawa J; Itamochi H; Shimada M; Takahashi M; Kamazawa S; Sato S; Akeshima R; Terakawa N
    Clin Cancer Res; 2001 Apr; 7(4):892-5. PubMed ID: 11309338
    [TBL] [Abstract][Full Text] [Related]  

  • 17. XIAP regulates Akt activity and caspase-3-dependent cleavage during cisplatin-induced apoptosis in human ovarian epithelial cancer cells.
    Asselin E; Mills GB; Tsang BK
    Cancer Res; 2001 Mar; 61(5):1862-8. PubMed ID: 11280739
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fatty acid synthase and AKT pathway signaling in a subset of papillary thyroid cancers.
    Uddin S; Siraj AK; Al-Rasheed M; Ahmed M; Bu R; Myers JN; Al-Nuaim A; Al-Sobhi S; Al-Dayel F; Bavi P; Hussain AR; Al-Kuraya KS
    J Clin Endocrinol Metab; 2008 Oct; 93(10):4088-97. PubMed ID: 18682509
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth.
    Altomare DA; You H; Xiao GH; Ramos-Nino ME; Skele KL; De Rienzo A; Jhanwar SC; Mossman BT; Kane AB; Testa JR
    Oncogene; 2005 Sep; 24(40):6080-9. PubMed ID: 15897870
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of the phosphatidylinositol 3'-kinase/PTEN/Akt kinase pathway in tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in non-small cell lung cancer cells.
    Kandasamy K; Srivastava RK
    Cancer Res; 2002 Sep; 62(17):4929-37. PubMed ID: 12208743
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.