141 related articles for article (PubMed ID: 15808238)
1. Discovery of ligands by a combination of computational and NMR-based screening: RNA as an example target.
Mayer M; James TL
Methods Enzymol; 2005; 394():571-87. PubMed ID: 15808238
[TBL] [Abstract][Full Text] [Related]
2. Structure-based development of target-specific compound libraries.
Orry AJ; Abagyan RA; Cavasotto CN
Drug Discov Today; 2006 Mar; 11(5-6):261-6. PubMed ID: 16580603
[TBL] [Abstract][Full Text] [Related]
3. Design and implementation of an ribonucleic acid (RNA) directed fragment library.
Bodoor K; Boyapati V; Gopu V; Boisdore M; Allam K; Miller J; Treleaven WD; Weldeghiorghis T; Aboul-ela F
J Med Chem; 2009 Jun; 52(12):3753-61. PubMed ID: 19445516
[TBL] [Abstract][Full Text] [Related]
4. Use of 19F NMR spectroscopy to screen chemical libraries for ligands that bind to proteins.
Tengel T; Fex T; Emtenas H; Almqvist F; Sethson I; Kihlberg J
Org Biomol Chem; 2004 Mar; 2(5):725-31. PubMed ID: 14985813
[TBL] [Abstract][Full Text] [Related]
5. [Development of antituberculous drugs: current status and future prospects].
Tomioka H; Namba K
Kekkaku; 2006 Dec; 81(12):753-74. PubMed ID: 17240921
[TBL] [Abstract][Full Text] [Related]
6. A knowledge-based weighting approach to ligand-based virtual screening.
Stiefl N; Zaliani A
J Chem Inf Model; 2006; 46(2):587-96. PubMed ID: 16562987
[TBL] [Abstract][Full Text] [Related]
7. TINS, target immobilized NMR screening: an efficient and sensitive method for ligand discovery.
Vanwetswinkel S; Heetebrij RJ; van Duynhoven J; Hollander JG; Filippov DV; Hajduk PJ; Siegal G
Chem Biol; 2005 Feb; 12(2):207-16. PubMed ID: 15734648
[TBL] [Abstract][Full Text] [Related]
8. A structure-based strategy to identify new molecular scaffolds targeting the bacterial ribosomal A-site.
Foloppe N; Chen IJ; Davis B; Hold A; Morley D; Howes R
Bioorg Med Chem; 2004 Mar; 12(5):935-47. PubMed ID: 14980606
[TBL] [Abstract][Full Text] [Related]
9. Design and NMR-based screening of LEF, a library of chemical fragments with different local environment of fluorine.
Vulpetti A; Hommel U; Landrum G; Lewis R; Dalvit C
J Am Chem Soc; 2009 Sep; 131(36):12949-59. PubMed ID: 19702332
[TBL] [Abstract][Full Text] [Related]
10. Novel approach to structure-based pharmacophore search using computational geometry and shape matching techniques.
Ebalunode JO; Ouyang Z; Liang J; Zheng W
J Chem Inf Model; 2008 Apr; 48(4):889-901. PubMed ID: 18396858
[TBL] [Abstract][Full Text] [Related]
11. Importance of molecular computer modeling in anticancer drug development.
Geromichalos GD
J BUON; 2007 Sep; 12 Suppl 1():S101-18. PubMed ID: 17935268
[TBL] [Abstract][Full Text] [Related]
12. NMR-based characterization of phenothiazines as a RNA binding scaffold.
Mayer M; James TL
J Am Chem Soc; 2004 Apr; 126(13):4453-60. PubMed ID: 15053636
[TBL] [Abstract][Full Text] [Related]
13. Competition STD NMR for the detection of high-affinity ligands and NMR-based screening.
Wang YS; Liu D; Wyss DF
Magn Reson Chem; 2004 Jun; 42(6):485-9. PubMed ID: 15137040
[TBL] [Abstract][Full Text] [Related]
14. Discovery of aminoglycoside mimetics by NMR-based screening of Escherichia coli A-site RNA.
Yu L; Oost TK; Schkeryantz JM; Yang J; Janowick D; Fesik SW
J Am Chem Soc; 2003 Apr; 125(15):4444-50. PubMed ID: 12683814
[TBL] [Abstract][Full Text] [Related]
15. Application of NMR and EPR methods to the study of RNA.
Qin PZ; Dieckmann T
Curr Opin Struct Biol; 2004 Jun; 14(3):350-9. PubMed ID: 15193316
[TBL] [Abstract][Full Text] [Related]
16. Combined use of computational chemistry, NMR screening, and X-ray crystallography for identification and characterization of fluorophilic protein environments.
Vulpetti A; Schiering N; Dalvit C
Proteins; 2010 Dec; 78(16):3281-91. PubMed ID: 20886466
[TBL] [Abstract][Full Text] [Related]
17. High-throughput nuclear magnetic resonance-based screening.
Hajduk PJ; Gerfin T; Boehlen JM; Häberli M; Marek D; Fesik SW
J Med Chem; 1999 Jul; 42(13):2315-7. PubMed ID: 10395471
[TBL] [Abstract][Full Text] [Related]
18. SeleX-CS: a new consensus scoring algorithm for hit discovery and lead optimization.
Bar-Haim S; Aharon A; Ben-Moshe T; Marantz Y; Senderowitz H
J Chem Inf Model; 2009 Mar; 49(3):623-33. PubMed ID: 19231809
[TBL] [Abstract][Full Text] [Related]
19. Practical aspects of NMR-based fragment screening.
Lepre CA
Methods Enzymol; 2011; 493():219-39. PubMed ID: 21371593
[TBL] [Abstract][Full Text] [Related]
20. Virtual screening and scaffold hopping based on GRID molecular interaction fields.
Ahlström MM; Ridderström M; Luthman K; Zamora I
J Chem Inf Model; 2005; 45(5):1313-23. PubMed ID: 16180908
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]