263 related articles for article (PubMed ID: 15809185)
1. Less is more: the human microdosing concept.
Garner RC
Drug Discov Today; 2005 Apr; 10(7):449-51. PubMed ID: 15809185
[No Abstract] [Full Text] [Related]
2. Improved early clinical development through human microdosing studies.
Wilding IR; Bell JA
Drug Discov Today; 2005 Jul; 10(13):890-4. PubMed ID: 15993808
[No Abstract] [Full Text] [Related]
3. Big physics, small doses: the use of AMS and PET in human microdosing of development drugs.
Lappin G; Garner RC
Nat Rev Drug Discov; 2003 Mar; 2(3):233-40. PubMed ID: 12612650
[TBL] [Abstract][Full Text] [Related]
4. American College of Clinical Pharmacology position statement on the use of microdosing in the drug development process.
Bertino JS; Greenberg HE; Reed MD;
J Clin Pharmacol; 2007 Apr; 47(4):418-22. PubMed ID: 17389550
[No Abstract] [Full Text] [Related]
5. Commentary on ACCP position statement on the use of microdosing in the drug development process.
Rowland M
J Clin Pharmacol; 2007 Dec; 47(12):1595-6; author reply 1597-8. PubMed ID: 18048576
[No Abstract] [Full Text] [Related]
6. The future of drug safety testing: expanding the view and narrowing the focus.
Stevens JL; Baker TK
Drug Discov Today; 2009 Feb; 14(3-4):162-7. PubMed ID: 19100337
[TBL] [Abstract][Full Text] [Related]
7. Evaluation of microdosing to assess pharmacokinetic linearity in rats using liquid chromatography-tandem mass spectrometry.
Balani SK; Nagaraja NV; Qian MG; Costa AO; Daniels JS; Yang H; Shimoga PR; Wu JT; Gan LS; Lee FW; Miwa GT
Drug Metab Dispos; 2006 Mar; 34(3):384-8. PubMed ID: 16326814
[TBL] [Abstract][Full Text] [Related]
8. Pharma goes to work. Introduction.
Mervis J
Science; 2005 Jul; 309(5735):721. PubMed ID: 16051780
[No Abstract] [Full Text] [Related]
9. PK/PD modelling and simulations: utility in drug development.
Rajman I
Drug Discov Today; 2008 Apr; 13(7-8):341-6. PubMed ID: 18405847
[TBL] [Abstract][Full Text] [Related]
10. Synthetic library design.
Huwe CM
Drug Discov Today; 2006 Aug; 11(15-16):763-7. PubMed ID: 16846805
[TBL] [Abstract][Full Text] [Related]
11. Reverse-engineering clinical biology. A peacetime dividend yields drug trials on virtual patients.
Stix G
Sci Am; 2003 Feb; 288(2):18-9. PubMed ID: 12561454
[No Abstract] [Full Text] [Related]
12. Positron emission tomography for use in microdosing studies.
Wagner CC; Müller M; Lappin G; Langer O
Curr Opin Drug Discov Devel; 2008 Jan; 11(1):104-10. PubMed ID: 18175273
[TBL] [Abstract][Full Text] [Related]
13. Application of in silico, in vitro and preclinical pharmacokinetic data for the effective and efficient prediction of human pharmacokinetics.
Grime KH; Barton P; McGinnity DF
Mol Pharm; 2013 Apr; 10(4):1191-206. PubMed ID: 23253040
[TBL] [Abstract][Full Text] [Related]
14. [Research projects of pharmaceutical companies].
Okuyama S
Nihon Yakurigaku Zasshi; 2008 Aug; 132(2):77-8. PubMed ID: 18792463
[No Abstract] [Full Text] [Related]
15. Modelling of the blood-brain barrier in drug discovery and development.
Cecchelli R; Berezowski V; Lundquist S; Culot M; Renftel M; Dehouck MP; Fenart L
Nat Rev Drug Discov; 2007 Aug; 6(8):650-61. PubMed ID: 17667956
[TBL] [Abstract][Full Text] [Related]
16. The pivotal role of drug metabolism and pharmacokinetics in the discovery and development of new medicines.
Alavijeh MS; Palmer AM
IDrugs; 2004 Aug; 7(8):755-63. PubMed ID: 15334309
[TBL] [Abstract][Full Text] [Related]
17. [Control, drug preparation and dosage in the designing of experiments (author's transl)].
Chen X
Zhonghua Yi Xue Za Zhi; 1981 Jun; 61(6):335-8. PubMed ID: 6796231
[No Abstract] [Full Text] [Related]
18. "Getting the dose right": facts, a blueprint, and encouragements.
Peck CC; Cross JT
Clin Pharmacol Ther; 2007 Jul; 82(1):12-4. PubMed ID: 17571068
[No Abstract] [Full Text] [Related]
19. Evaluation and recommendations on adaptive dose-ranging trials: highlights from the PhRMA Adaptive Dose-Ranging Studies Working Group.
Pinheiro J
J Clin Pharmacol; 2010 Sep; 50(9 Suppl):47S-49S. PubMed ID: 20881216
[No Abstract] [Full Text] [Related]
20. Safety and efficacy: the role of chemistry, manufacturing, and controls in pharmaceutical drug development.
DiFeo TJ
Drug Dev Ind Pharm; 2004 Mar; 30(3):247-57. PubMed ID: 15109024
[No Abstract] [Full Text] [Related]
[Next] [New Search]
