237 related articles for article (PubMed ID: 15809335)
21. Understanding the structural and energetic basis of inhibitor and substrate bound to the full-length NS3/4A: insights from molecular dynamics simulation, binding free energy calculation and network analysis.
Xue W; Wang M; Jin X; Liu H; Yao X
Mol Biosyst; 2012 Oct; 8(10):2753-65. PubMed ID: 22833015
[TBL] [Abstract][Full Text] [Related]
22. Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target.
Lescar J; Luo D; Xu T; Sampath A; Lim SP; Canard B; Vasudevan SG
Antiviral Res; 2008 Nov; 80(2):94-101. PubMed ID: 18674567
[TBL] [Abstract][Full Text] [Related]
23. In vitro antiviral activity of SCH446211 (SCH6), a novel inhibitor of the hepatitis C virus NS3 serine protease.
Liu R; Abid K; Pichardo J; Pazienza V; Ingravallo P; Kong R; Agrawal S; Bogen S; Saksena A; Cheng KC; Prongay A; Njoroge FG; Baroudy BM; Negro F
J Antimicrob Chemother; 2007 Jan; 59(1):51-8. PubMed ID: 17151003
[TBL] [Abstract][Full Text] [Related]
24. Fluoroquinolones inhibit HCV by targeting its helicase.
Khan IA; Siddiqui S; Rehmani S; Kazmi SU; Ali SH
Antivir Ther; 2012; 17(3):467-76. PubMed ID: 22293206
[TBL] [Abstract][Full Text] [Related]
25. The NS3 protein of hepatitis C virus induces caspase-8-mediated apoptosis independent of its protease or helicase activities.
Prikhod'ko EA; Prikhod'ko GG; Siegel RM; Thompson P; Major ME; Cohen JI
Virology; 2004 Nov; 329(1):53-67. PubMed ID: 15476874
[TBL] [Abstract][Full Text] [Related]
26. Enzymatic characterization of membrane-associated hepatitis C virus NS3-4A heterocomplex serine protease activity expressed in human cells.
Hamill P; Jean F
Biochemistry; 2005 May; 44(17):6586-96. PubMed ID: 15850392
[TBL] [Abstract][Full Text] [Related]
27. Suppression of hepatitis C virus by the flavonoid quercetin is mediated by inhibition of NS3 protease activity.
Bachmetov L; Gal-Tanamy M; Shapira A; Vorobeychik M; Giterman-Galam T; Sathiyamoorthy P; Golan-Goldhirsh A; Benhar I; Tur-Kaspa R; Zemel R
J Viral Hepat; 2012 Feb; 19(2):e81-8. PubMed ID: 22239530
[TBL] [Abstract][Full Text] [Related]
28. Inhibitors of hepatitis C virus NS3.4A protease. Effect of P4 capping groups on inhibitory potency and pharmacokinetics.
Perni RB; Chandorkar G; Cottrell KM; Gates CA; Lin C; Lin K; Luong YP; Maxwell JP; Murcko MA; Pitlik J; Rao G; Schairer WC; Van Drie J; Wei Y
Bioorg Med Chem Lett; 2007 Jun; 17(12):3406-11. PubMed ID: 17482818
[TBL] [Abstract][Full Text] [Related]
29. Synthesis of new acridone derivatives, inhibitors of NS3 helicase, which efficiently and specifically inhibit subgenomic HCV replication.
Stankiewicz-Drogoń A; Dörner B; Erker T; Boguszewska-Chachulska AM
J Med Chem; 2010 Apr; 53(8):3117-26. PubMed ID: 20337460
[TBL] [Abstract][Full Text] [Related]
30. Real-time monitoring of RNA helicase activity using fluorescence resonance energy transfer in vitro.
Tani H; Fujita O; Furuta A; Matsuda Y; Miyata R; Akimitsu N; Tanaka J; Tsuneda S; Sekiguchi Y; Noda N
Biochem Biophys Res Commun; 2010 Feb; 393(1):131-6. PubMed ID: 20117090
[TBL] [Abstract][Full Text] [Related]
31. Role of the DExH motif of the Japanese encephalitis virus and hepatitis C virus NS3 proteins in the ATPase and RNA helicase activities.
Utama A; Shimizu H; Hasebe F; Morita K; Igarashi A; Shoji I; Matsuura Y; Hatsu M; Takamizawa K; Hagiwara A; Miyamura T
Virology; 2000 Aug; 273(2):316-24. PubMed ID: 10915602
[TBL] [Abstract][Full Text] [Related]
32. Crystal structure and activity of Kunjin virus NS3 helicase; protease and helicase domain assembly in the full length NS3 protein.
Mastrangelo E; Milani M; Bollati M; Selisko B; Peyrane F; Pandini V; Sorrentino G; Canard B; Konarev PV; Svergun DI; de Lamballerie X; Coutard B; Khromykh AA; Bolognesi M
J Mol Biol; 2007 Sep; 372(2):444-55. PubMed ID: 17658551
[TBL] [Abstract][Full Text] [Related]
33. Development of a replicon-based phenotypic assay for assessing the drug susceptibilities of HCV NS3 protease genes from clinical isolates.
Qi X; Bae A; Liu S; Yang H; Sun SC; Harris J; Delaney W; Miller M; Mo H
Antiviral Res; 2009 Feb; 81(2):166-73. PubMed ID: 19063924
[TBL] [Abstract][Full Text] [Related]
34. Hepatitis C virus NS3 NTPase/helicase: different stereoselectivity in nucleoside triphosphate utilisation suggests that NTPase and helicase activities are coupled by a nucleotide-dependent rate limiting step.
Locatelli GA; Gosselin G; Spadari S; Maga G
J Mol Biol; 2001 Nov; 313(4):683-94. PubMed ID: 11697897
[TBL] [Abstract][Full Text] [Related]
35. Specific targeting of hepatitis C virus NS3 RNA helicase. Discovery of the potent and selective competitive nucleotide-mimicking inhibitor QU663.
Maga G; Gemma S; Fattorusso C; Locatelli GA; Butini S; Persico M; Kukreja G; Romano MP; Chiasserini L; Savini L; Novellino E; Nacci V; Spadari S; Campiani G
Biochemistry; 2005 Jul; 44(28):9637-44. PubMed ID: 16008349
[TBL] [Abstract][Full Text] [Related]
36. Investigation of glycine alpha-ketoamide HCV NS3 protease inhibitors: effect of carboxylic acid isosteres.
Han W; Jiang X; Hu Z; Wasserman ZR; Decicco CP
Bioorg Med Chem Lett; 2005 Aug; 15(15):3487-90. PubMed ID: 15982872
[TBL] [Abstract][Full Text] [Related]
37. Phenylglycine as a novel P2 scaffold in hepatitis C virus NS3 protease inhibitors.
Ortqvist P; Peterson SD; Kerblom E; Gossas T; Sabnis YA; Fransson R; Lindeberg G; Helena Danielson U; Karlén A; Sandström A
Bioorg Med Chem; 2007 Feb; 15(3):1448-74. PubMed ID: 17113777
[TBL] [Abstract][Full Text] [Related]
38. An ELISA for RNA helicase activity: application as an assay of the NS3 helicase of hepatitis C virus.
Hsu CC; Hwang LH; Huang YW; Chi WK; Chu YD; Chen DS
Biochem Biophys Res Commun; 1998 Dec; 253(3):594-9. PubMed ID: 9918773
[TBL] [Abstract][Full Text] [Related]
39. Characterization of classical swine fever virus (CSFV) nonstructural protein 3 (NS3) helicase activity and its modulation by CSFV RNA-dependent RNA polymerase.
Wen G; Xue J; Shen Y; Zhang C; Pan Z
Virus Res; 2009 Apr; 141(1):63-70. PubMed ID: 19185595
[TBL] [Abstract][Full Text] [Related]
40. A time-resolved, internally quenched fluorescence assay to characterize inhibition of hepatitis C virus nonstructural protein 3-4A protease at low enzyme concentrations.
Mao SS; DiMuzio J; McHale C; Burlein C; Olsen D; Carroll SS
Anal Biochem; 2008 Feb; 373(1):1-8. PubMed ID: 18022380
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
