BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

662 related articles for article (PubMed ID: 15809347)

  • 1. The essential role of histone H3 Lys9 di-methylation and MeCP2 binding in MGMT silencing with poor DNA methylation of the promoter CpG island.
    Zhao W; Soejima H; Higashimoto K; Nakagawachi T; Urano T; Kudo S; Matsukura S; Matsuo S; Joh K; Mukai T
    J Biochem; 2005 Mar; 137(3):431-40. PubMed ID: 15809347
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Silencing effect of CpG island hypermethylation and histone modifications on O6-methylguanine-DNA methyltransferase (MGMT) gene expression in human cancer.
    Nakagawachi T; Soejima H; Urano T; Zhao W; Higashimoto K; Satoh Y; Matsukura S; Kudo S; Kitajima Y; Harada H; Furukawa K; Matsuzaki H; Emi M; Nakabeppu Y; Miyazaki K; Sekiguchi M; Mukai T
    Oncogene; 2003 Dec; 22(55):8835-44. PubMed ID: 14647440
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transcriptional gene silencing promotes DNA hypermethylation through a sequential change in chromatin modifications in cancer cells.
    Stirzaker C; Song JZ; Davidson B; Clark SJ
    Cancer Res; 2004 Jun; 64(11):3871-7. PubMed ID: 15172996
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CpG methylation-dependent repression of the human O6-methylguanine-DNA methyltransferase gene linked to chromatin structure alteration.
    Bhakat KK; Mitra S
    Carcinogenesis; 2003 Aug; 24(8):1337-45. PubMed ID: 12807730
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia.
    Magdinier F; Wolffe AP
    Proc Natl Acad Sci U S A; 2001 Apr; 98(9):4990-5. PubMed ID: 11309512
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Influence of CpG island methylation status in O6-methylguanine-DNA methyltransferase expression of oral cancer cell lines.
    Murakami J; Asaumi J; Maki Y; Tsujigiwa H; Nagatsuka H; Kokeguchi S; Inoue T; Kawasaki S; Tanaka N; MacPhee D; Matsubara N; Kishi K
    Oncol Rep; 2004 Aug; 12(2):339-45. PubMed ID: 15254699
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), a gene encoding an inhibitor of matrix metalloproteinases in human glioma cells.
    Konduri SD; Srivenugopal KS; Yanamandra N; Dinh DH; Olivero WC; Gujrati M; Foster DC; Kisiel W; Ali-Osman F; Kondraganti S; Lakka SS; Rao JS
    Oncogene; 2003 Jul; 22(29):4509-16. PubMed ID: 12881707
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Heterogeneity in the modification and involvement of chromatin components of the CpG island of the silenced human CDH1 gene in cancer cells.
    Koizume S; Tachibana K; Sekiya T; Hirohashi S; Shiraishi M
    Nucleic Acids Res; 2002 Nov; 30(21):4770-80. PubMed ID: 12409468
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers.
    Yuan J; Luo RZ; Fujii S; Wang L; Hu W; Andreeff M; Pan Y; Kadota M; Oshimura M; Sahin AA; Issa JP; Bast RC; Yu Y
    Cancer Res; 2003 Jul; 63(14):4174-80. PubMed ID: 12874023
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Epigenetic regulation of the MGMT and hMSH6 DNA repair genes in cells resistant to methylating agents.
    Bearzatto A; Szadkowski M; Macpherson P; Jiricny J; Karran P
    Cancer Res; 2000 Jun; 60(12):3262-70. PubMed ID: 10866320
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Altered chromatin structure associated with methylation-induced gene silencing in cancer cells: correlation of accessibility, methylation, MeCP2 binding and acetylation.
    Nguyen CT; Gonzales FA; Jones PA
    Nucleic Acids Res; 2001 Nov; 29(22):4598-606. PubMed ID: 11713309
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer.
    Kondo Y; Shen L; Issa JP
    Mol Cell Biol; 2003 Jan; 23(1):206-15. PubMed ID: 12482974
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells.
    Kim TY; Jong HS; Song SH; Dimtchev A; Jeong SJ; Lee JW; Kim TY; Kim NK; Jung M; Bang YJ
    Oncogene; 2003 Jun; 22(25):3943-51. PubMed ID: 12813468
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia.
    Esteller M; Hamilton SR; Burger PC; Baylin SB; Herman JG
    Cancer Res; 1999 Feb; 59(4):793-7. PubMed ID: 10029064
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inactivation of O6-methylguanine-DNA methyltransferase by promoter CpG island hypermethylation in gastric cancers.
    Bae SI; Lee HS; Kim SH; Kim WH
    Br J Cancer; 2002 Jun; 86(12):1888-92. PubMed ID: 12085181
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Silencing of imprinted CDKN1C gene expression is associated with loss of CpG and histone H3 lysine 9 methylation at DMR-LIT1 in esophageal cancer.
    Soejima H; Nakagawachi T; Zhao W; Higashimoto K; Urano T; Matsukura S; Kitajima Y; Takeuchi M; Nakayama M; Oshimura M; Miyazaki K; Joh K; Mukai T
    Oncogene; 2004 May; 23(25):4380-8. PubMed ID: 15007390
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inactivation of p57KIP2 by regional promoter hypermethylation and histone deacetylation in human tumors.
    Kikuchi T; Toyota M; Itoh F; Suzuki H; Obata T; Yamamoto H; Kakiuchi H; Kusano M; Issa JP; Tokino T; Imai K
    Oncogene; 2002 Apr; 21(17):2741-9. PubMed ID: 11965547
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Methylation of selected CpGs in the human O6-methylguanine-DNA methyltransferase promoter region as a marker of gene silencing.
    Danam RP; Qian XC; Howell SR; Brent TP
    Mol Carcinog; 1999 Feb; 24(2):85-9. PubMed ID: 10078935
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Methylation-mediated proviral silencing is associated with MeCP2 recruitment and localized histone H3 deacetylation.
    Lorincz MC; Schübeler D; Groudine M
    Mol Cell Biol; 2001 Dec; 21(23):7913-22. PubMed ID: 11689684
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regional methylation of the 5' end CpG island of BRCA1 is associated with reduced gene expression in human somatic cells.
    Magdinier F; Billard LM; Wittmann G; Frappart L; Benchaïb M; Lenoir GM; Guérin JF; Dante R
    FASEB J; 2000 Aug; 14(11):1585-94. PubMed ID: 10928993
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 34.