228 related articles for article (PubMed ID: 15826607)
1. Clofibrate and perfluorodecanoate both upregulate the expression of the pregnane X receptor but oppositely affect its ligand-dependent induction on cytochrome P450 3A23.
Ma Y; Sachdeva K; Liu J; Song X; Li Y; Yang D; Deng R; Chichester CO; Yan B
Biochem Pharmacol; 2005 May; 69(9):1363-71. PubMed ID: 15826607
[TBL] [Abstract][Full Text] [Related]
2. Dexamethasone transcriptionally increases the expression of the pregnane X receptor and synergistically enhances pyrethroid esfenvalerate in the induction of cytochrome P450 3A23.
Shi D; Yang D; Yan B
Biochem Pharmacol; 2010 Oct; 80(8):1274-83. PubMed ID: 20599767
[TBL] [Abstract][Full Text] [Related]
3. Simultaneous substitution of phenylalanine-305 and aspartate-318 of rat pregnane X receptor with the corresponding human residues abolishes the ability to transactivate the CYP3A23 promoter.
Song X; Li Y; Liu J; Mukundan M; Yan B
J Pharmacol Exp Ther; 2005 Feb; 312(2):571-82. PubMed ID: 15367577
[TBL] [Abstract][Full Text] [Related]
4. Pregnane X receptor-dependent and -independent effects of 2-acetylaminofluorene on cytochrome P450 3A23 expression and liver cell proliferation.
Sparfel L; Payen L; Gilot D; Sidaway J; Morel F; Guillouzo A; Fardel O
Biochem Biophys Res Commun; 2003 Jan; 300(2):278-84. PubMed ID: 12504080
[TBL] [Abstract][Full Text] [Related]
5. Comparison of the hepatic and thyroid gland effects of sodium phenobarbital in wild type and constitutive androstane receptor (CAR) knockout rats and pregnenolone-16α-carbonitrile in wild type and pregnane X receptor (PXR) knockout rats.
Haines C; Chatham LR; Vardy A; Elcombe CR; Foster JR; Lake BG
Toxicology; 2018 May; 400-401():20-27. PubMed ID: 29548889
[TBL] [Abstract][Full Text] [Related]
6. Two-stage glucocorticoid induction of CYP3A23 through both the glucocorticoid and pregnane X receptors.
Huss JM; Kasper CB
Mol Pharmacol; 2000 Jul; 58(1):48-57. PubMed ID: 10860926
[TBL] [Abstract][Full Text] [Related]
7. Postnatal expression and induction by pregnenolone-16alpha-carbonitrile of the organic anion-transporting polypeptide 2 in rat liver.
Guo GL; Johnson DR; Klaassen CD
Drug Metab Dispos; 2002 Mar; 30(3):283-8. PubMed ID: 11854146
[TBL] [Abstract][Full Text] [Related]
8. Induction of cytochrome P450 3A by paclitaxel in mice: pivotal role of the nuclear xenobiotic receptor, pregnane X receptor.
Nallani SC; Goodwin B; Maglich JM; Buckley DJ; Buckley AR; Desai PB
Drug Metab Dispos; 2003 May; 31(5):681-4. PubMed ID: 12695359
[TBL] [Abstract][Full Text] [Related]
9. Cytoplasmic localization of pregnane X receptor and ligand-dependent nuclear translocation in mouse liver.
Squires EJ; Sueyoshi T; Negishi M
J Biol Chem; 2004 Nov; 279(47):49307-14. PubMed ID: 15347657
[TBL] [Abstract][Full Text] [Related]
10. Effects of atorvastatin metabolites on induction of drug-metabolizing enzymes and membrane transporters through human pregnane X receptor.
Hoffart E; Ghebreghiorghis L; Nussler AK; Thasler WE; Weiss TS; Schwab M; Burk O
Br J Pharmacol; 2012 Mar; 165(5):1595-608. PubMed ID: 21913896
[TBL] [Abstract][Full Text] [Related]
11. Environmental xenobiotics and the antihormones cyproterone acetate and spironolactone use the nuclear hormone pregnenolone X receptor to activate the CYP3A23 hormone response element.
Schuetz EG; Brimer C; Schuetz JD
Mol Pharmacol; 1998 Dec; 54(6):1113-7. PubMed ID: 9855641
[TBL] [Abstract][Full Text] [Related]
12. CYP3A induction by liver x receptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor.
Shenoy SD; Spencer TA; Mercer-Haines NA; Alipour M; Gargano MD; Runge-Morris M; Kocarek TA
Drug Metab Dispos; 2004 Jan; 32(1):66-71. PubMed ID: 14709622
[TBL] [Abstract][Full Text] [Related]
13. Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation.
Zhang H; LeCulyse E; Liu L; Hu M; Matoney L; Zhu W; Yan B
Arch Biochem Biophys; 1999 Aug; 368(1):14-22. PubMed ID: 10415106
[TBL] [Abstract][Full Text] [Related]
14. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
[TBL] [Abstract][Full Text] [Related]
15. Pregnane X receptor: molecular basis for species differences in CYP3A induction by xenobiotics.
LeCluyse EL
Chem Biol Interact; 2001 May; 134(3):283-9. PubMed ID: 11336976
[TBL] [Abstract][Full Text] [Related]
16. Desmethoxyyangonin and dihydromethysticin are two major pharmacological kavalactones with marked activity on the induction of CYP3A23.
Ma Y; Sachdeva K; Liu J; Ford M; Yang D; Khan IA; Chichester CO; Yan B
Drug Metab Dispos; 2004 Nov; 32(11):1317-24. PubMed ID: 15282211
[TBL] [Abstract][Full Text] [Related]
17. Rat PXR reporter-gene activity correlates with the induction of CYP3A in rat precision-cut liver slices.
Cui X; Thomas A; Montgomery D; Gu C; Morrison RA; White RE; Cheng KC
Comb Chem High Throughput Screen; 2005 Jun; 8(4):341-6. PubMed ID: 16101010
[TBL] [Abstract][Full Text] [Related]
18. Perfluorocarboxylic acids induce cytochrome P450 enzymes in mouse liver through activation of PPAR-alpha and CAR transcription factors.
Cheng X; Klaassen CD
Toxicol Sci; 2008 Nov; 106(1):29-36. PubMed ID: 18648086
[TBL] [Abstract][Full Text] [Related]
19. A human immunodeficiency virus protease inhibitor is a novel functional inhibitor of human pregnane X receptor.
Healan-Greenberg C; Waring JF; Kempf DJ; Blomme EA; Tirona RG; Kim RB
Drug Metab Dispos; 2008 Mar; 36(3):500-7. PubMed ID: 18096673
[TBL] [Abstract][Full Text] [Related]
20. Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis.
Fisher CD; Jackson JP; Lickteig AJ; Augustine LM; Cherrington NJ
Arch Toxicol; 2008 Dec; 82(12):959-64. PubMed ID: 18488193
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
