BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 15826836)

  • 1. ETV6-NTRK3: a chimeric protein tyrosine kinase with transformation activity in multiple cell lineages.
    Lannon CL; Sorensen PH
    Semin Cancer Biol; 2005 Jun; 15(3):215-23. PubMed ID: 15826836
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The ETV6-NTRK3 gene fusion encodes a chimeric protein tyrosine kinase that transforms NIH3T3 cells.
    Wai DH; Knezevich SR; Lucas T; Jansen B; Kay RJ; Sorensen PH
    Oncogene; 2000 Feb; 19(7):906-15. PubMed ID: 10702799
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The insulin-like growth factor I receptor is required for Akt activation and suppression of anoikis in cells transformed by the ETV6-NTRK3 chimeric tyrosine kinase.
    Martin MJ; Melnyk N; Pollard M; Bowden M; Leong H; Podor TJ; Gleave M; Sorensen PH
    Mol Cell Biol; 2006 Mar; 26(5):1754-69. PubMed ID: 16478996
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cellular transformation and activation of the phosphoinositide-3-kinase-Akt cascade by the ETV6-NTRK3 chimeric tyrosine kinase requires c-Src.
    Jin W; Yun C; Hobbie A; Martin MJ; Sorensen PH; Kim SJ
    Cancer Res; 2007 Apr; 67(7):3192-200. PubMed ID: 17409427
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ETV6-NTRK3 transformation requires insulin-like growth factor 1 receptor signaling and is associated with constitutive IRS-1 tyrosine phosphorylation.
    Morrison KB; Tognon CE; Garnett MJ; Deal C; Sorensen PH
    Oncogene; 2002 Aug; 21(37):5684-95. PubMed ID: 12173038
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutations in the SAM domain of the ETV6-NTRK3 chimeric tyrosine kinase block polymerization and transformation activity.
    Tognon CE; Mackereth CD; Somasiri AM; McIntosh LP; Sorensen PH
    Mol Cell Biol; 2004 Jun; 24(11):4636-50. PubMed ID: 15143160
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma.
    Knezevich SR; McFadden DE; Tao W; Lim JF; Sorensen PH
    Nat Genet; 1998 Feb; 18(2):184-7. PubMed ID: 9462753
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The chimeric protein tyrosine kinase ETV6-NTRK3 requires both Ras-Erk1/2 and PI3-kinase-Akt signaling for fibroblast transformation.
    Tognon C; Garnett M; Kenward E; Kay R; Morrison K; Sorensen PH
    Cancer Res; 2001 Dec; 61(24):8909-16. PubMed ID: 11751416
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ETV6-NTRK3-mediated breast epithelial cell transformation is blocked by targeting the IGF1R signaling pathway.
    Tognon CE; Somasiri AM; Evdokimova VE; Trigo G; Uy EE; Melnyk N; Carboni JM; Gottardis MM; Roskelley CD; Pollak M; Sorensen PH
    Cancer Res; 2011 Feb; 71(3):1060-70. PubMed ID: 21148487
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A highly conserved NTRK3 C-terminal sequence in the ETV6-NTRK3 oncoprotein binds the phosphotyrosine binding domain of insulin receptor substrate-1: an essential interaction for transformation.
    Lannon CL; Martin MJ; Tognon CE; Jin W; Kim SJ; Sorensen PH
    J Biol Chem; 2004 Feb; 279(8):6225-34. PubMed ID: 14668342
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A tripartite complex composed of ETV6-NTRK3, IRS1 and IGF1R is required for ETV6-NTRK3-mediated membrane localization and transformation.
    Tognon CE; Martin MJ; Moradian A; Trigo G; Rotblat B; Cheng SW; Pollard M; Uy E; Chow C; Carboni JM; Gottardis MM; Pollak M; Morin GB; Sorensen PH
    Oncogene; 2012 Mar; 31(10):1334-40. PubMed ID: 21804605
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ETV6: a versatile player in leukemogenesis.
    Bohlander SK
    Semin Cancer Biol; 2005 Jun; 15(3):162-74. PubMed ID: 15826831
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A fluorescence in situ hybridization study of ETV6-NTRK3 fusion gene in secretory breast carcinoma.
    Makretsov N; He M; Hayes M; Chia S; Horsman DE; Sorensen PH; Huntsman DG
    Genes Chromosomes Cancer; 2004 Jun; 40(2):152-7. PubMed ID: 15101049
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ETV6-NTRK3 gene fusions and trisomy 11 establish a histogenetic link between mesoblastic nephroma and congenital fibrosarcoma.
    Knezevich SR; Garnett MJ; Pysher TJ; Beckwith JB; Grundy PE; Sorensen PH
    Cancer Res; 1998 Nov; 58(22):5046-8. PubMed ID: 9823307
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Congenital-infantile fibrosarcoma. A clinicopathologic study of 10 cases and molecular detection of the ETV6-NTRK3 fusion transcripts using paraffin-embedded tissues.
    Sheng WQ; Hisaoka M; Okamoto S; Tanaka A; Meis-Kindblom JM; Kindblom LG; Ishida T; Nojima T; Hashimoto H
    Am J Clin Pathol; 2001 Mar; 115(3):348-55. PubMed ID: 11242790
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transformation of Ba/F3 cells and Rat-1 cells by ETV6/ARG.
    Iijima Y; Okuda K; Tojo A; Tri NK; Setoyama M; Sakaki Y; Asano S; Tokunaga K; Kruh GD; Sato Y
    Oncogene; 2002 Jun; 21(28):4374-83. PubMed ID: 12080468
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Congenital mesoblastic nephroma t(12;15) is associated with ETV6-NTRK3 gene fusion: cytogenetic and molecular relationship to congenital (infantile) fibrosarcoma.
    Rubin BP; Chen CJ; Morgan TW; Xiao S; Grier HE; Kozakewich HP; Perez-Atayde AR; Fletcher JA
    Am J Pathol; 1998 Nov; 153(5):1451-8. PubMed ID: 9811336
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of a SRC-like tyrosine kinase gene, FRK, fused with ETV6 in a patient with acute myelogenous leukemia carrying a t(6;12)(q21;p13) translocation.
    Hosoya N; Qiao Y; Hangaishi A; Wang L; Nannya Y; Sanada M; Kurokawa M; Chiba S; Hirai H; Ogawa S
    Genes Chromosomes Cancer; 2005 Mar; 42(3):269-79. PubMed ID: 15611931
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutation of the salt bridge-forming residues in the ETV6-SAM domain interface blocks ETV6-NTRK3-induced cellular transformation.
    Cetinbas N; Huang-Hobbs H; Tognon C; Leprivier G; An J; McKinney S; Bowden M; Chow C; Gleave M; McIntosh LP; Sorensen PH
    J Biol Chem; 2013 Sep; 288(39):27940-50. PubMed ID: 23798677
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mammary analogue secretory carcinoma of salivary glands with high-grade transformation: report of 3 cases with the ETV6-NTRK3 gene fusion and analysis of TP53, β-catenin, EGFR, and CCND1 genes.
    Skálová A; Vanecek T; Majewska H; Laco J; Grossmann P; Simpson RH; Hauer L; Andrle P; Hosticka L; Branžovský J; Michal M
    Am J Surg Pathol; 2014 Jan; 38(1):23-33. PubMed ID: 24145651
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.