BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

256 related articles for article (PubMed ID: 15831492)

  • 1. Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells.
    Pruitt K; Ulkü AS; Frantz K; Rojas RJ; Muniz-Medina VM; Rangnekar VM; Der CJ; Shields JM
    J Biol Chem; 2005 Jun; 280(24):23363-70. PubMed ID: 15831492
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Opposing roles of the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades in Ras-mediated downregulation of tropomyosin.
    Shields JM; Mehta H; Pruitt K; Der CJ
    Mol Cell Biol; 2002 Apr; 22(7):2304-17. PubMed ID: 11884615
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The downregulation of the pro-apoptotic protein Par-4 is critical for Ras-induced survival and tumor progression.
    Barradas M; Monjas A; Diaz-Meco MT; Serrano M; Moscat J
    EMBO J; 1999 Nov; 18(22):6362-9. PubMed ID: 10562548
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Essential role of Raf in Ras transformation and deregulation of matrix metalloproteinase expression in ovarian epithelial cells.
    Ulkü AS; Schäfer R; Der CJ
    Mol Cancer Res; 2003 Dec; 1(14):1077-88. PubMed ID: 14707291
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hypermethylation downregulates Runx3 gene expression and its restoration suppresses gastric epithelial cell growth by inducing p27 and caspase3 in human gastric cancer.
    Chen W; Gao N; Shen Y; Cen JN
    J Gastroenterol Hepatol; 2010 Apr; 25(4):823-31. PubMed ID: 20492341
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Oncogenic Ras blocks anoikis by activation of a novel effector pathway independent of phosphatidylinositol 3-kinase.
    McFall A; Ulkü A; Lambert QT; Kusa A; Rogers-Graham K; Der CJ
    Mol Cell Biol; 2001 Aug; 21(16):5488-99. PubMed ID: 11463831
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Loss of transgelin in breast and colon tumors and in RIE-1 cells by Ras deregulation of gene expression through Raf-independent pathways.
    Shields JM; Rogers-Graham K; Der CJ
    J Biol Chem; 2002 Mar; 277(12):9790-9. PubMed ID: 11773051
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Negative regulation of Par-4 by oncogenic Ras is essential for cellular transformation.
    Qiu SG; Krishnan S; el-Guendy N; Rangnekar VM
    Oncogene; 1999 Nov; 18(50):7115-23. PubMed ID: 10597313
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ras inactivation of the retinoblastoma pathway by distinct mechanisms in NIH 3T3 fibroblast and RIE-1 epithelial cells.
    Pruitt K; Pestell RG; Der CJ
    J Biol Chem; 2000 Dec; 275(52):40916-24. PubMed ID: 11007784
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Post-transcriptional down-regulation of ROCKI/Rho-kinase through an MEK-dependent pathway leads to cytoskeleton disruption in Ras-transformed fibroblasts.
    Pawlak G; Helfman DM
    Mol Biol Cell; 2002 Jan; 13(1):336-47. PubMed ID: 11809843
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhanced cathepsin L expression is mediated by different Ras effector pathways in fibroblasts and epithelial cells.
    Collette J; Ulku AS; Der CJ; Jones A; Erickson AH
    Int J Cancer; 2004 Nov; 112(2):190-9. PubMed ID: 15352030
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Roles of the Ras-MEK-mitogen-activated protein kinase and phosphatidylinositol 3-kinase-Akt-mTOR pathways in Jaagsiekte sheep retrovirus-induced transformation of rodent fibroblast and epithelial cell lines.
    Maeda N; Fu W; Ortin A; de las Heras M; Fan H
    J Virol; 2005 Apr; 79(7):4440-50. PubMed ID: 15767444
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) inhibitors restore anoikis sensitivity in human breast cancer cell lines with a constitutively activated extracellular-regulated kinase (ERK) pathway.
    Fukazawa H; Noguchi K; Murakami Y; Uehara Y
    Mol Cancer Ther; 2002 Mar; 1(5):303-9. PubMed ID: 12489846
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells.
    Oldham SM; Clark GJ; Gangarosa LM; Coffey RJ; Der CJ
    Proc Natl Acad Sci U S A; 1996 Jul; 93(14):6924-8. PubMed ID: 8692920
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cooperative regulation of the cell division cycle by the protein kinases RAF and AKT.
    Mirza AM; Gysin S; Malek N; Nakayama K; Roberts JM; McMahon M
    Mol Cell Biol; 2004 Dec; 24(24):10868-81. PubMed ID: 15572689
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Silencing of BNIP3 results from promoter methylation by DNA methyltransferase 1 induced by the mitogen-activated protein kinase pathway.
    An HJ; Lee H; Paik SG
    Mol Cells; 2011 Jun; 31(6):579-83. PubMed ID: 21573703
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A raf-independent epidermal growth factor receptor autocrine loop is necessary for Ras transformation of rat intestinal epithelial cells.
    Gangarosa LM; Sizemore N; Graves-Deal R; Oldham SM; Der CJ; Coffey RJ
    J Biol Chem; 1997 Jul; 272(30):18926-31. PubMed ID: 9228072
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ras mediates radioresistance through both phosphatidylinositol 3-kinase-dependent and Raf-dependent but mitogen-activated protein kinase/extracellular signal-regulated kinase kinase-independent signaling pathways.
    Grana TM; Rusyn EV; Zhou H; Sartor CI; Cox AD
    Cancer Res; 2002 Jul; 62(14):4142-50. PubMed ID: 12124353
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transformation by oncogenic RAS sensitizes human colon cells to TRAIL-induced apoptosis by up-regulating death receptor 4 and death receptor 5 through a MEK-dependent pathway.
    Drosopoulos KG; Roberts ML; Cermak L; Sasazuki T; Shirasawa S; Andera L; Pintzas A
    J Biol Chem; 2005 Jun; 280(24):22856-67. PubMed ID: 15757891
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Suppression of PTEN expression is essential for antiapoptosis and cellular transformation by oncogenic Ras.
    Vasudevan KM; Burikhanov R; Goswami A; Rangnekar VM
    Cancer Res; 2007 Nov; 67(21):10343-50. PubMed ID: 17974977
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.