These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

238 related articles for article (PubMed ID: 15835903)

  • 1. Molecular recognition of the substrate diphosphate group governs product diversity in trichodiene synthase mutants.
    Vedula LS; Rynkiewicz MJ; Pyun HJ; Coates RM; Cane DE; Christianson DW
    Biochemistry; 2005 Apr; 44(16):6153-63. PubMed ID: 15835903
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of arginine-304 in the diphosphate-triggered active site closure mechanism of trichodiene synthase.
    Vedula LS; Cane DE; Christianson DW
    Biochemistry; 2005 Sep; 44(38):12719-27. PubMed ID: 16171386
    [TBL] [Abstract][Full Text] [Related]  

  • 3. X-ray crystal structures of D100E trichodiene synthase and its pyrophosphate complex reveal the basis for terpene product diversity.
    Rynkiewicz MJ; Cane DE; Christianson DW
    Biochemistry; 2002 Feb; 41(6):1732-41. PubMed ID: 11827517
    [TBL] [Abstract][Full Text] [Related]  

  • 4. An Aromatic Cluster in the Active Site of
    Ronnebaum TA; Gardner SM; Christianson DW
    Biochemistry; 2020 Dec; 59(50):4744-4754. PubMed ID: 33270439
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure of trichodiene synthase from Fusarium sporotrichioides provides mechanistic inferences on the terpene cyclization cascade.
    Rynkiewicz MJ; Cane DE; Christianson DW
    Proc Natl Acad Sci U S A; 2001 Nov; 98(24):13543-8. PubMed ID: 11698643
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Two pockets in the active site of maize sesquiterpene synthase TPS4 carry out sequential parts of the reaction scheme resulting in multiple products.
    Köllner TG; O'Maille PE; Gatto N; Boland W; Gershenzon J; Degenhardt J
    Arch Biochem Biophys; 2006 Apr; 448(1-2):83-92. PubMed ID: 16297849
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure of epi-isozizaene synthase from Streptomyces coelicolor A3(2), a platform for new terpenoid cyclization templates.
    Aaron JA; Lin X; Cane DE; Christianson DW
    Biochemistry; 2010 Mar; 49(8):1787-97. PubMed ID: 20131801
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanism of monoterpene cyclization: stereochemical aspects of the transformation of noncyclizable substrate analogs by recombinant (-)-limonene synthase, (+)-bornyl diphosphate synthase, and (-)-pinene synthase.
    Schwab W; Williams DC; Davis EM; Croteau R
    Arch Biochem Biophys; 2001 Aug; 392(1):123-36. PubMed ID: 11469803
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Exploring biosynthetic diversity with trichodiene synthase.
    Vedula LS; Zhao Y; Coates RM; Koyama T; Cane DE; Christianson DW
    Arch Biochem Biophys; 2007 Oct; 466(2):260-6. PubMed ID: 17678871
    [TBL] [Abstract][Full Text] [Related]  

  • 10. X-ray crystal structure of aristolochene synthase from Aspergillus terreus and evolution of templates for the cyclization of farnesyl diphosphate.
    Shishova EY; Di Costanzo L; Cane DE; Christianson DW
    Biochemistry; 2007 Feb; 46(7):1941-51. PubMed ID: 17261032
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Point mutation of (+)-germacrene A synthase from Ixeris dentata.
    Chang YJ; Jin J; Nam HY; Kim SU
    Biotechnol Lett; 2005 Mar; 27(5):285-8. PubMed ID: 15834787
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes.
    Blank PN; Barrow GH; Chou WKW; Duan L; Cane DE; Christianson DW
    Biochemistry; 2017 Oct; 56(43):5798-5811. PubMed ID: 28967743
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evolution of enzymatic activity in the enolase superfamily: structural and mutagenic studies of the mechanism of the reaction catalyzed by o-succinylbenzoate synthase from Escherichia coli.
    Klenchin VA; Taylor Ringia EA; Gerlt JA; Rayment I
    Biochemistry; 2003 Dec; 42(49):14427-33. PubMed ID: 14661953
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Insights into the structural basis of substrate recognition by histidinol-phosphate aminotransferase from Corynebacterium glutamicum.
    Marienhagen J; Sandalova T; Sahm H; Eggeling L; Schneider G
    Acta Crystallogr D Biol Crystallogr; 2008 Jun; 64(Pt 6):675-85. PubMed ID: 18560156
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evolution of enzymatic activity in the enolase superfamily: functional studies of the promiscuous o-succinylbenzoate synthase from Amycolatopsis.
    Taylor Ringia EA; Garrett JB; Thoden JB; Holden HM; Rayment I; Gerlt JA
    Biochemistry; 2004 Jan; 43(1):224-9. PubMed ID: 14705949
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Yeast sterol C24-methyltransferase: role of highly conserved tyrosine-81 in catalytic competence studied by site-directed mutagenesis and thermodynamic analysis.
    Nes WD; Jayasimha P; Song Z
    Arch Biochem Biophys; 2008 Sep; 477(2):313-23. PubMed ID: 18555004
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif.
    Vedula LS; Jiang J; Zakharian T; Cane DE; Christianson DW
    Arch Biochem Biophys; 2008 Jan; 469(2):184-94. PubMed ID: 17996718
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biosynthesis of monoterpenes: partial purification, characterization, and mechanism of action of 1,8-cineole synthase.
    Croteau R; Alonso WR; Koepp AE; Johnson MA
    Arch Biochem Biophys; 1994 Feb; 309(1):184-92. PubMed ID: 8117108
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evolution of catalytic microenvironment governs substrate and product diversity in trichodiene synthase and other terpene fold enzymes.
    Kumari I; Ahmed M; Akhter Y
    Biochimie; 2018 Jan; 144():9-20. PubMed ID: 29017925
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Substrate-assisted movement of the catalytic Lys 215 during domain closure: site-directed mutagenesis studies of human 3-phosphoglycerate kinase.
    Flachner B; Varga A; Szabó J; Barna L; Hajdú I; Gyimesi G; Závodszky P; Vas M
    Biochemistry; 2005 Dec; 44(51):16853-65. PubMed ID: 16363799
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.