These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

134 related articles for article (PubMed ID: 1585469)

  • 21. Thiopurine S-methyltransferase genotype predicts azathioprine-induced myelotoxicity in kidney transplant recipients.
    Formea CM; Myers-Huentelman H; Wu R; Crabtree J; Fujita S; Hemming A; Reed A; Howard R; Karlix JL
    Am J Transplant; 2004 Nov; 4(11):1810-7. PubMed ID: 15476481
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Comparison of three methods for measuring thiopurine methyltransferase activity in red blood cells and human leukemia cells.
    Karim H; Appell ML; Fotoohi A
    J Chromatogr B Analyt Technol Biomed Life Sci; 2013 Nov; 939():80-5. PubMed ID: 24113235
    [TBL] [Abstract][Full Text] [Related]  

  • 23. A randomized trial of cyclosporine and prednisolone versus cyclosporine, azathioprine, and prednisolone in primary cadaveric renal transplantation.
    Lindholm A; Albrechtsen D; Tufveson G; Karlberg I; Persson NH; Groth CG
    Transplantation; 1992 Oct; 54(4):624-31. PubMed ID: 1412754
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Thiopurine methyltransferase and 6-thioguanine nucleotide measurement: early experience of use in clinical practice.
    Gearry RB; Barclay ML; Roberts RL; Harraway J; Zhang M; Pike LS; George PM; Florkowski CM
    Intern Med J; 2005 Oct; 35(10):580-5. PubMed ID: 16207256
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Hypoxanthine guanine phosphoribosyltransferase activity is related to 6-thioguanine nucleotide concentrations and thiopurine-induced leukopenia in the treatment of inflammatory bowel disease.
    Ding L; Zhang FB; Liu H; Gao X; Bi HC; Wang XD; Chen BL; Zhang Y; Zhao LZ; Zhong GP; Hu PJ; Chen MH; Huang M
    Inflamm Bowel Dis; 2012 Jan; 18(1):63-73. PubMed ID: 21381155
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Thiopurine dose in intermediate and normal metabolizers of thiopurine methyltransferase may differ three-fold.
    Gardiner SJ; Gearry RB; Begg EJ; Zhang M; Barclay ML
    Clin Gastroenterol Hepatol; 2008 Jun; 6(6):654-60; quiz 604. PubMed ID: 18467186
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Thiopurine methyltransferase genotype and activity cannot predict outcomes of azathioprine maintenance therapy for antineutrophil cytoplasmic antibody associated vasculitis: A retrospective cohort study.
    Hessels AC; Rutgers A; Sanders JSF; Stegeman CA
    PLoS One; 2018; 13(4):e0195524. PubMed ID: 29630648
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Frequency distribution of thiopurine S-methyltransferase activity in red blood cells of a healthy Japanese population.
    Kubota T; Nishida A; Takeuchi K; Iida T; Yokota H; Higashi K; Nakahara K; Hanai H; Iga T
    Ther Drug Monit; 2004 Jun; 26(3):319-21. PubMed ID: 15167635
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Monitoring of thiopurine methyltransferase activity in postsurgical patients with Crohn's disease during 1 year of treatment with azathioprine or mesalazine.
    Dilger K; Schaeffeler E; Lukas M; Strauch U; Herfarth H; Müller R; Schwab M
    Ther Drug Monit; 2007 Feb; 29(1):1-5. PubMed ID: 17304143
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Red Blood cell IMPDH activity in adults and children with or without azathioprine: Relationship between thiopurine metabolites, ITPA and TPMT activities.
    Citterio-Quentin A; El Mahmoudi A; Perret T; Conway A; Ryan A; Beringer A; Lachaux A; Boulieu R
    Basic Clin Pharmacol Toxicol; 2019 May; 124(5):600-606. PubMed ID: 30451390
    [TBL] [Abstract][Full Text] [Related]  

  • 31. High TPMT enzyme activity does not explain drug resistance due to preferential 6-methylmercaptopurine production in patients on thiopurine treatment.
    van Egmond R; Chin P; Zhang M; Sies CW; Barclay ML
    Aliment Pharmacol Ther; 2012 May; 35(10):1181-9. PubMed ID: 22486532
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Thiopurine drugs in the treatment of childhood leukaemia: the influence of inherited thiopurine methyltransferase activity on drug metabolism and cytotoxicity.
    Lennard L; Welch JC; Lilleyman JS
    Br J Clin Pharmacol; 1997 Nov; 44(5):455-61. PubMed ID: 9384462
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus.
    Relling MV; Hancock ML; Rivera GK; Sandlund JT; Ribeiro RC; Krynetski EY; Pui CH; Evans WE
    J Natl Cancer Inst; 1999 Dec; 91(23):2001-8. PubMed ID: 10580024
    [TBL] [Abstract][Full Text] [Related]  

  • 34. [Hematotoxicity caused by azathioprine genetically determined and aggravated by xanthine oxidase deficiency in a patient following renal transplantation].
    Serre-Debeauvais F; Bayle F; Amirou M; Bechtel Y; Boujet C; Vialtel P; Bessard G
    Presse Med; 1995 Jun; 24(21):987-8. PubMed ID: 7667222
    [TBL] [Abstract][Full Text] [Related]  

  • 35. A 6-thioguanine nucleotide threshold level of 400 pmol/8 x 10(8) erythrocytes predicts azathioprine refractoriness in patients with inflammatory bowel disease and normal TPMT activity.
    Roblin X; Peyrin-Biroulet L; Phelip JM; Nancey S; Flourie B
    Am J Gastroenterol; 2008 Dec; 103(12):3115-22. PubMed ID: 19086961
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Pharmacogenetics of acute azathioprine toxicity: relationship to thiopurine methyltransferase genetic polymorphism.
    Lennard L; Van Loon JA; Weinshilboum RM
    Clin Pharmacol Ther; 1989 Aug; 46(2):149-54. PubMed ID: 2758725
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Thiopurine methyltransferase (TPMT) genotype distribution in azathioprine-tolerant and -intolerant patients with various disorders. The impact of TPMT genotyping in predicting toxicity.
    Reuther LO; Vainer B; Sonne J; Larsen NE
    Eur J Clin Pharmacol; 2004 Jan; 59(11):797-801. PubMed ID: 14634700
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Oral azathioprine for recalcitrant pediatric atopic dermatitis: clinical response and thiopurine monitoring.
    Caufield M; Tom WL
    J Am Acad Dermatol; 2013 Jan; 68(1):29-35. PubMed ID: 22892285
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The effect of allopurinol and low-dose thiopurine combination therapy on the activity of three pivotal thiopurine metabolizing enzymes: results from a prospective pharmacological study.
    Seinen ML; van Asseldonk DP; de Boer NK; Losekoot N; Smid K; Mulder CJ; Bouma G; Peters GJ; van Bodegraven AA
    J Crohns Colitis; 2013 Nov; 7(10):812-9. PubMed ID: 23317929
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Thiopurine S-methyltransferase activity in Japanese subjects: metabolic activity of 6-mercaptopurine 6-methylation in different TPMT genotypes.
    Nishida A; Kubota T; Yamada Y; Higashi K; Kitamura K; Nakahara K; Iga T
    Clin Chim Acta; 2002 Sep; 323(1-2):147-50. PubMed ID: 12135816
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.