These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 15855530)

  • 1. Behavior of thymidylate kinase toward monophosphate metabolites and its role in the metabolism of 1-(2'-deoxy-2'-fluoro-beta-L-arabinofuranosyl)-5-methyluracil (Clevudine) and 2',3'-didehydro-2',3'-dideoxythymidine in cells.
    Hu R; Li L; Degrève B; Dutschman GE; Lam W; Cheng YC
    Antimicrob Agents Chemother; 2005 May; 49(5):2044-9. PubMed ID: 15855530
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphorylation of the anti-hepatitis B nucleoside analog 1-(2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl)-5-iodouracil (FIAU) by human cytosolic and mitochondrial thymidine kinase and implications for cytotoxicity.
    Wang J; Eriksson S
    Antimicrob Agents Chemother; 1996 Jun; 40(6):1555-7. PubMed ID: 8726039
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Assessment of the effect of phosphorylated metabolites of anti-human immunodeficiency virus and anti-hepatitis B virus pyrimidine analogs on the behavior of human deoxycytidylate deaminase.
    Liou JY; Krishnan P; Hsieh CC; Dutschman GE; Cheng YC
    Mol Pharmacol; 2003 Jan; 63(1):105-10. PubMed ID: 12488542
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Unique metabolism of a novel antiviral L-nucleoside analog, 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil: a substrate for both thymidine kinase and deoxycytidine kinase.
    Liu SH; Grove KL; Cheng YC
    Antimicrob Agents Chemother; 1998 Apr; 42(4):833-9. PubMed ID: 9559792
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanisms of substrate selectivity for Bacillus anthracis thymidylate kinase.
    Carnrot C; Wang L; Topalis D; Eriksson S
    Protein Sci; 2008 Sep; 17(9):1486-93. PubMed ID: 18523102
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nucleosides. 146. 1-Methyl-5-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil, the C-nucleoside isostere of the potent antiviral agent 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)thymine (FMAU). Studies directed toward the synthesis of 2'-deoxy-2'-substituted arabino nucleosides. 6.
    Pankiewicz KW; Nawrot B; Gadler H; Price RW; Watanabe KA
    J Med Chem; 1987 Dec; 30(12):2314-6. PubMed ID: 2824777
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Kinetic studies with N2-phenylguanines and with L-thymidine indicate that herpes simplex virus type-1 thymidine kinase and thymidylate kinase share a common active site.
    Maga G; Focher F; Wright GE; Capobianco M; Garbesi A; Bendiscioli A; Spadari S
    Biochem J; 1994 Aug; 302 ( Pt 1)(Pt 1):279-82. PubMed ID: 8068016
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-ethyluracil. A highly selective antiherpes simplex agent.
    Mansuri MM; Ghazzouli I; Chen MS; Howell HG; Brodfuehrer PR; Benigni DA; Martin JC
    J Med Chem; 1987 May; 30(5):867-71. PubMed ID: 3033244
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ethanol decreases the efficiency of phosphorylation of thymidine kinase in a human T-lymphocytic cell line.
    Prakash O; Tang ZY; Zhou P; Peng X; Kolls J; Shellito JE; Nelson S
    Alcohol Clin Exp Res; 2002 Mar; 26(3):295-302. PubMed ID: 11923581
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Fialuridine and its metabolites inhibit DNA polymerase gamma at sites of multiple adjacent analog incorporation, decrease mtDNA abundance, and cause mitochondrial structural defects in cultured hepatoblasts.
    Lewis W; Levine ES; Griniuviene B; Tankersley KO; Colacino JM; Sommadossi JP; Watanabe KA; Perrino FW
    Proc Natl Acad Sci U S A; 1996 Apr; 93(8):3592-7. PubMed ID: 8622980
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Intracellular metabolism and persistence of the anti-human immunodeficiency virus activity of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine, a novel thymidine analog.
    Paintsil E; Dutschman GE; Hu R; Grill SP; Lam W; Baba M; Tanaka H; Cheng YC
    Antimicrob Agents Chemother; 2007 Nov; 51(11):3870-9. PubMed ID: 17724147
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pharmacokinetics of 1-(2-deoxy-2-fluoro-beta-L-arabinofuranosyl)-5-methyluracil (L-FMAU) in rats.
    Wright JD; Ma T; Chu CK; Boudinot FD
    Pharm Res; 1995 Sep; 12(9):1350-3. PubMed ID: 8570534
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolism of 4'-azidothymidine. A compound with potent and selective activity against the human immunodeficiency virus.
    Chen MS; Suttmann RT; Wu JC; Prisbe EJ
    J Biol Chem; 1992 Jan; 267(1):257-60. PubMed ID: 1730594
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Different modes of transport for 3H-thymidine, 3H-FLT, and 3H-FMAU in proliferating and nonproliferating human tumor cells.
    Plotnik DA; Emerick LE; Krohn KA; Unadkat JD; Schwartz JL
    J Nucl Med; 2010 Sep; 51(9):1464-71. PubMed ID: 20720049
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Preclinical investigation of L-FMAU as an anti-hepatitis B virus agent.
    Chu CK; Boudinot FD; Peek SF; Hong JH; Choi Y; Korba BE; Gerin JL; Cote PJ; Tennant BC; Cheng YC
    Antivir Ther; 1998; 3(Suppl 3):113-21. PubMed ID: 10726061
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure-guided engineering of human thymidine kinase 2 as a positron emission tomography reporter gene for enhanced phosphorylation of non-natural thymidine analog reporter probe.
    Campbell DO; Yaghoubi SS; Su Y; Lee JT; Auerbach MS; Herschman H; Satyamurthy N; Czernin J; Lavie A; Radu CG
    J Biol Chem; 2012 Jan; 287(1):446-454. PubMed ID: 22074768
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An optimized thymidylate kinase assay, based on enzymatically synthesized 5-[125I]iododeoxyuridine monophosphate and its application to an immunological study of herpes simplex virus thymidine-thymidylate kinases.
    Karlström AR; Gronowitz JS
    Anal Biochem; 1987 May; 162(2):500-10. PubMed ID: 3037945
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of hepatitis B virus by a novel L-nucleoside, 2'-fluoro-5-methyl-beta-L-arabinofuranosyl uracil.
    Balakrishna Pai S; Liu SH; Zhu YL; Chu CK; Cheng YC
    Antimicrob Agents Chemother; 1996 Feb; 40(2):380-6. PubMed ID: 8834884
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tracking cellular stress with labeled FMAU reflects changes in mitochondrial TK2.
    Tehrani OS; Douglas KA; Lawhorn-Crews JM; Shields AF
    Eur J Nucl Med Mol Imaging; 2008 Aug; 35(8):1480-8. PubMed ID: 18265975
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cyclosaligenyl-2',3'-didehydro-2',3'-dideoxythymidine monophosphate: efficient intracellular delivery of d4TMP.
    Balzarini J; Aquaro S; Knispel T; Rampazzo C; Bianchi V; Perno CF; De Clercq E; Meier C
    Mol Pharmacol; 2000 Nov; 58(5):928-35. PubMed ID: 11040039
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.