BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 15855531)

  • 21. Discovery and characterization of substituted diphenyl heterocyclic compounds as potent and selective inhibitors of hepatitis C virus replication.
    Huang P; Goff DA; Huang Q; Martinez A; Xu X; Crowder S; Issakani SD; Anderson E; Sheng N; Achacoso P; Yen A; Kinsella T; Darwish IS; Kolluri R; Hong H; Qu K; Stauffer E; Goldstein E; Singh R; Payan DG; Lu HH
    Antimicrob Agents Chemother; 2008 Apr; 52(4):1419-29. PubMed ID: 18227176
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Synthesis and characterization of 1'-C-cyano-2'-fluoro-2'-C-methyl pyrimidine nucleosides as HCV polymerase inhibitors.
    Kirschberg TA; Mish MR; Zhang L; Squires NH; Wang KY; Cho A; Feng JY; Fenaux M; Babusis D; Park Y; Ray AS; Kim CU
    Bioorg Med Chem Lett; 2015 Mar; 25(5):1040-3. PubMed ID: 25650256
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Synthesis of New Indanyl Nucleoside Analogues and their Biological Evaluation on Hepatitis C Virus (HCV) Replicon.
    Gómez ME; Gentile EA; Martini MF; Cuestas ML; Mathet VL; Moltrasio GY; Moglioni AG
    Molecules; 2019 Mar; 24(5):. PubMed ID: 30862130
    [TBL] [Abstract][Full Text] [Related]  

  • 24. High-throughput screening of HCV RNA replication inhibitors by means of a reporter replicon system.
    Hao W; Duggal R
    Methods Mol Biol; 2009; 510():243-50. PubMed ID: 19009266
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Activity and the metabolic activation pathway of the potent and selective hepatitis C virus pronucleotide inhibitor PSI-353661.
    Furman PA; Murakami E; Niu C; Lam AM; Espiritu C; Bansal S; Bao H; Tolstykh T; Micolochick Steuer H; Keilman M; Zennou V; Bourne N; Veselenak RL; Chang W; Ross BS; Du J; Otto MJ; Sofia MJ
    Antiviral Res; 2011 Aug; 91(2):120-32. PubMed ID: 21600932
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Dynamics of subgenomic hepatitis C virus replicon RNA levels in Huh-7 cells after exposure to nucleoside antimetabolites.
    Stuyver LJ; McBrayer TR; Tharnish PM; Hassan AE; Chu CK; Pankiewicz KW; Watanabe KA; Schinazi RF; Otto MJ
    J Virol; 2003 Oct; 77(19):10689-94. PubMed ID: 12970456
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Synthesis and anti-HCV activity of 3',4'-oxetane nucleosides.
    Chang W; Du J; Rachakonda S; Ross BS; Convers-Reignier S; Yau WT; Pons JF; Murakami E; Bao H; Steuer HM; Furman PA; Otto MJ; Sofia MJ
    Bioorg Med Chem Lett; 2010 Aug; 20(15):4539-43. PubMed ID: 20580554
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Establishment of a subgenomic replicon for bovine viral diarrhea virus in Huh-7 cells and modulation of interferon-regulated factor 3-mediated antiviral response.
    Horscroft N; Bellows D; Ansari I; Lai VC; Dempsey S; Liang D; Donis R; Zhong W; Hong Z
    J Virol; 2005 Mar; 79(5):2788-96. PubMed ID: 15708997
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The effect of ribavirin and IMPDH inhibitors on hepatitis C virus subgenomic replicon RNA.
    Zhou S; Liu R; Baroudy BM; Malcolm BA; Reyes GR
    Virology; 2003 Jun; 310(2):333-42. PubMed ID: 12781720
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Novel hepatitis C virus reporter replicon cell lines enable efficient antiviral screening against genotype 1a.
    Robinson M; Yang H; Sun SC; Peng B; Tian Y; Pagratis N; Greenstein AE; Delaney WE
    Antimicrob Agents Chemother; 2010 Aug; 54(8):3099-106. PubMed ID: 20516274
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Synthesis and antiviral properties of novel 7-heterocyclic substituted 7-deaza-adenine nucleoside inhibitors of Hepatitis C NS5B polymerase.
    Di Francesco ME; Avolio S; Pompei M; Pesci S; Monteagudo E; Pucci V; Giuliano C; Fiore F; Rowley M; Summa V
    Bioorg Med Chem; 2012 Aug; 20(15):4801-11. PubMed ID: 22770556
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Design and synthesis of novel carbocyclic versions of 2'-spirocyclopropyl ribonucleosides as potent anti-HCV agents.
    Oh CH; Kim E; Hong JH
    Nucleosides Nucleotides Nucleic Acids; 2011 Jun; 30(6):423-39. PubMed ID: 21780908
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Synthesis and anti-hepatitis C virus (HCV) activity of 3'-C-substituted-methyl pyrimidine and purine nucleosides.
    Choi WJ; Kim YM; Kim HO; Lee HW; Kim DE; Park KS; Chong Y; Jeong LS
    Bioorg Med Chem; 2010 Jul; 18(13):4812-20. PubMed ID: 20627592
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Synthesis and evaluation of S-acyl-2-thioethyl esters of modified nucleoside 5'-monophosphates as inhibitors of hepatitis C virus RNA replication.
    Prakash TP; Prhavc M; Eldrup AB; Cook PD; Carroll SS; Olsen DB; Stahlhut MW; Tomassini JE; MacCoss M; Galloway SM; Hilliard C; Bhat B
    J Med Chem; 2005 Feb; 48(4):1199-210. PubMed ID: 15715486
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Derivatives of imidazotriazine and pyrrolotriazine C-nucleosides as potential new anti-HCV agents.
    Draffan AG; Frey B; Fraser BH; Pool B; Gannon C; Tyndall EM; Cianci J; Harding M; Lilly M; Hufton R; Halim R; Jahangiri S; Bond S; Jeynes TP; Nguyen VT; Wirth V; Luttick A; Tilmanis D; Pryor M; Porter K; Morton CJ; Lin B; Duan J; Bethell RC; Kukolj G; Simoneau B; Tucker SP
    Bioorg Med Chem Lett; 2014 Nov; 24(21):4984-8. PubMed ID: 25288185
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Hairpin ribozymes in combination with siRNAs against highly conserved hepatitis C virus sequence inhibit RNA replication and protein translation from hepatitis C virus subgenomic replicons.
    Jarczak D; Korf M; Beger C; Manns MP; Krüger M
    FEBS J; 2005 Nov; 272(22):5910-22. PubMed ID: 16279954
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Selection and characterization of hepatitis C virus replicons dually resistant to the polymerase and protease inhibitors HCV-796 and boceprevir (SCH 503034).
    Flint M; Mullen S; Deatly AM; Chen W; Miller LZ; Ralston R; Broom C; Emini EA; Howe AY
    Antimicrob Agents Chemother; 2009 Feb; 53(2):401-11. PubMed ID: 18936191
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Evaluation of compound activity against hepatitis C virus in replicon systems.
    Yang G; Huang M
    Curr Protoc Pharmacol; 2010 Sep; Chapter 13():Unit 13B.1. PubMed ID: 22294366
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Persistent replication of hepatitis C virus replicons expressing the beta-lactamase reporter in subpopulations of highly permissive Huh7 cells.
    Murray EM; Grobler JA; Markel EJ; Pagnoni MF; Paonessa G; Simon AJ; Flores OA
    J Virol; 2003 Mar; 77(5):2928-35. PubMed ID: 12584317
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Prodrugs of imidazotriazine and pyrrolotriazine C-nucleosides can increase anti-HCV activity and enhance nucleotide triphosphate concentrations in vitro.
    Tyndall EM; Draffan AG; Frey B; Pool B; Halim R; Jahangiri S; Bond S; Wirth V; Luttick A; Tilmanis D; Thomas J; Porter K; Tucker SP
    Bioorg Med Chem Lett; 2015 Feb; 25(4):869-73. PubMed ID: 25592710
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.