221 related articles for article (PubMed ID: 15855639)
1. SCF(beta-TrCP1) controls Smad4 protein stability in pancreatic cancer cells.
Wan M; Huang J; Jhala NC; Tytler EM; Yang L; Vickers SM; Tang Y; Lu C; Wang N; Cao X
Am J Pathol; 2005 May; 166(5):1379-92. PubMed ID: 15855639
[TBL] [Abstract][Full Text] [Related]
2. Smad4 protein stability is regulated by ubiquitin ligase SCF beta-TrCP1.
Wan M; Tang Y; Tytler EM; Lu C; Jin B; Vickers SM; Yang L; Shi X; Cao X
J Biol Chem; 2004 Apr; 279(15):14484-7. PubMed ID: 14988407
[TBL] [Abstract][Full Text] [Related]
3. Acute myelogenous leukemia-derived SMAD4 mutations target the protein to ubiquitin-proteasome degradation.
Yang L; Wang N; Tang Y; Cao X; Wan M
Hum Mutat; 2006 Sep; 27(9):897-905. PubMed ID: 16865698
[TBL] [Abstract][Full Text] [Related]
4. Ubiquitination and proteolysis of cancer-derived Smad4 mutants by SCFSkp2.
Liang M; Liang YY; Wrighton K; Ungermannova D; Wang XP; Brunicardi FC; Liu X; Feng XH; Lin X
Mol Cell Biol; 2004 Sep; 24(17):7524-37. PubMed ID: 15314162
[TBL] [Abstract][Full Text] [Related]
5. A clinically relevant model of human pancreatic adenocarcinoma identifies patterns of metastasis associated with alterations of the TGF-beta/Smad4 signaling pathway.
Holloway S; Davis M; Jaber R; Fleming J
Int J Gastrointest Cancer; 2003; 33(1):61-9. PubMed ID: 12909738
[TBL] [Abstract][Full Text] [Related]
6. Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells.
Peng B; Fleming JB; Breslin T; Grau AM; Fojioka S; Abbruzzese JL; Evans DB; Ayers D; Wathen K; Wu T; Robertson KD; Chiao PJ
Clin Cancer Res; 2002 Nov; 8(11):3628-38. PubMed ID: 12429655
[TBL] [Abstract][Full Text] [Related]
7. Tumor suppressor gene Smad4/DPC4, its downstream target genes, and regulation of cell cycle.
Chiao PJ; Hunt KK; Grau AM; Abramian A; Fleming J; Zhang W; Breslin T; Abbruzzese JL; Evans DB
Ann N Y Acad Sci; 1999 Jun; 880():31-7. PubMed ID: 10415848
[TBL] [Abstract][Full Text] [Related]
8. Loss of Smad4 function in pancreatic tumors: C-terminal truncation leads to decreased stability.
Maurice D; Pierreux CE; Howell M; Wilentz RE; Owen MJ; Hill CS
J Biol Chem; 2001 Nov; 276(46):43175-81. PubMed ID: 11553622
[TBL] [Abstract][Full Text] [Related]
9. Differential expression of transforming growth factor beta receptors in human pancreatic adenocarcinoma.
Venkatasubbarao K; Ahmed MM; Mohiuddin M; Swiderski C; Lee E; Gower WR; Salhab KF; McGrath P; Strodel W; Freeman JW
Anticancer Res; 2000; 20(1A):43-51. PubMed ID: 10769633
[TBL] [Abstract][Full Text] [Related]
10. Induction of p21waf1 expression and growth inhibition by transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells.
Grau AM; Zhang L; Wang W; Ruan S; Evans DB; Abbruzzese JL; Zhang W; Chiao PJ
Cancer Res; 1997 Sep; 57(18):3929-34. PubMed ID: 9307274
[TBL] [Abstract][Full Text] [Related]
11. Targeting endogenous transforming growth factor beta receptor signaling in SMAD4-deficient human pancreatic carcinoma cells inhibits their invasive phenotype1.
Subramanian G; Schwarz RE; Higgins L; McEnroe G; Chakravarty S; Dugar S; Reiss M
Cancer Res; 2004 Aug; 64(15):5200-11. PubMed ID: 15289325
[TBL] [Abstract][Full Text] [Related]
12. BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.
Coyaud E; Mis M; Laurent EM; Dunham WH; Couzens AL; Robitaille M; Gingras AC; Angers S; Raught B
Mol Cell Proteomics; 2015 Jul; 14(7):1781-95. PubMed ID: 25900982
[TBL] [Abstract][Full Text] [Related]
13. Restoration of SMAD4 by gene therapy reverses the invasive phenotype in pancreatic adenocarcinoma cells.
Duda DG; Sunamura M; Lefter LP; Furukawa T; Yokoyama T; Yatsuoka T; Abe T; Inoue H; Motoi F; Egawa S; Matsuno S; Horii A
Oncogene; 2003 Oct; 22(44):6857-64. PubMed ID: 14534532
[TBL] [Abstract][Full Text] [Related]
14. High-throughput drug screening of the DPC4 tumor-suppressor pathway in human pancreatic cancer cells.
Sohn TA; Su GH; Ryu B; Yeo CJ; Kern SE
Ann Surg; 2001 May; 233(5):696-703. PubMed ID: 11323508
[TBL] [Abstract][Full Text] [Related]
15. A role for human MUC4 mucin gene, the ErbB2 ligand, as a target of TGF-beta in pancreatic carcinogenesis.
Jonckheere N; Perrais M; Mariette C; Batra SK; Aubert JP; Pigny P; Van Seuningen I
Oncogene; 2004 Jul; 23(34):5729-38. PubMed ID: 15184872
[TBL] [Abstract][Full Text] [Related]
16. Smad4 silencing in pancreatic cancer cell lines using stable RNA interference and gene expression profiles induced by transforming growth factor-beta.
Jazag A; Ijichi H; Kanai F; Imamura T; Guleng B; Ohta M; Imamura J; Tanaka Y; Tateishi K; Ikenoue T; Kawakami T; Arakawa Y; Miyagishi M; Taira K; Kawabe T; Omata M
Oncogene; 2005 Jan; 24(4):662-71. PubMed ID: 15592526
[TBL] [Abstract][Full Text] [Related]
17. Smad4/DPC4-mediated tumor suppression through suppression of angiogenesis.
Schwarte-Waldhoff I; Volpert OV; Bouck NP; Sipos B; Hahn SA; Klein-Scory S; Lüttges J; Klöppel G; Graeven U; Eilert-Micus C; Hintelmann A; Schmiegel W
Proc Natl Acad Sci U S A; 2000 Aug; 97(17):9624-9. PubMed ID: 10944227
[TBL] [Abstract][Full Text] [Related]
18. Genetic alterations of the transforming growth factor beta receptor genes in pancreatic and biliary adenocarcinomas.
Goggins M; Shekher M; Turnacioglu K; Yeo CJ; Hruban RH; Kern SE
Cancer Res; 1998 Dec; 58(23):5329-32. PubMed ID: 9850059
[TBL] [Abstract][Full Text] [Related]
19. The SMAD4 protein and prognosis of pancreatic ductal adenocarcinoma.
Tascilar M; Skinner HG; Rosty C; Sohn T; Wilentz RE; Offerhaus GJ; Adsay V; Abrams RA; Cameron JL; Kern SE; Yeo CJ; Hruban RH; Goggins M
Clin Cancer Res; 2001 Dec; 7(12):4115-21. PubMed ID: 11751510
[TBL] [Abstract][Full Text] [Related]
20. Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor beta signaling by targeting Smads to the ubiquitin-proteasome pathway.
Xu J; Attisano L
Proc Natl Acad Sci U S A; 2000 Apr; 97(9):4820-5. PubMed ID: 10781087
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
