174 related articles for article (PubMed ID: 15857137)
1. Structure-activity relationships of fluorinated lysophosphatidic acid analogues.
Xu Y; Aoki J; Shimizu K; Umezu-Goto M; Hama K; Takanezawa Y; Yu S; Mills GB; Arai H; Qian L; Prestwich GD
J Med Chem; 2005 May; 48(9):3319-27. PubMed ID: 15857137
[TBL] [Abstract][Full Text] [Related]
2. Synthesis of monofluorinated analogues of lysophosphatidic acid.
Xu Y; Qian L; Prestwich GD
J Org Chem; 2003 Jun; 68(13):5320-30. PubMed ID: 12816494
[TBL] [Abstract][Full Text] [Related]
3. Enantioselective responses to a phosphorothioate analogue of lysophosphatidic acid with LPA3 receptor-selective agonist activity.
Qian L; Xu Y; Hasegawa Y; Aoki J; Mills GB; Prestwich GD
J Med Chem; 2003 Dec; 46(26):5575-8. PubMed ID: 14667211
[TBL] [Abstract][Full Text] [Related]
4. Alkyl lysophosphatidic acid and fluoromethylene phosphonate analogs as metabolically-stabilized agonists for LPA receptors.
Xu Y; Tanaka M; Arai H; Aoki J; Prestwich GD
Bioorg Med Chem Lett; 2004 Nov; 14(21):5323-8. PubMed ID: 15454220
[TBL] [Abstract][Full Text] [Related]
5. Phosphorothioate analogues of alkyl lysophosphatidic acid as LPA3 receptor-selective agonists.
Qian L; Xu Y; Simper T; Jiang G; Aoki J; Umezu-Goto M; Arai H; Yu S; Mills GB; Tsukahara R; Makarova N; Fujiwara Y; Tigyi G; Prestwich GD
ChemMedChem; 2006 Mar; 1(3):376-83. PubMed ID: 16892372
[TBL] [Abstract][Full Text] [Related]
6. Synthesis of migration-resistant hydroxyethoxy analogues of lysophosphatidic acid.
Qian L; Xu Y; Arai H; Aoki J; McIntyre TM; Prestwich GD
Org Lett; 2003 Nov; 5(24):4685-8. PubMed ID: 14627415
[TBL] [Abstract][Full Text] [Related]
7. Phosphorothioate analogs of sn-2 radyl lysophosphatidic acid (LPA): metabolically stabilized LPA receptor agonists.
Jiang G; Inoue A; Aoki J; Prestwich GD
Bioorg Med Chem Lett; 2013 Mar; 23(6):1865-9. PubMed ID: 23395664
[TBL] [Abstract][Full Text] [Related]
8. Phosphonothioate and fluoromethylene phosphonate analogues of cyclic phosphatidic acid: Novel antagonists of lysophosphatidic acid receptors.
Xu Y; Jiang G; Tsukahara R; Fujiwara Y; Tigyi G; Prestwich GD
J Med Chem; 2006 Aug; 49(17):5309-15. PubMed ID: 16913720
[TBL] [Abstract][Full Text] [Related]
9. Lysophosphatidic acid-induced Ca2+ mobilization in human A431 cells: structure-activity analysis.
Jalink K; Hengeveld T; Mulder S; Postma FR; Simon MF; Chap H; van der Marel GA; van Boom JH; van Blitterswijk WJ; Moolenaar WH
Biochem J; 1995 Apr; 307 ( Pt 2)(Pt 2):609-16. PubMed ID: 7733903
[TBL] [Abstract][Full Text] [Related]
10. New metabolically stabilized analogues of lysophosphatidic acid: agonists, antagonists and enzyme inhibitors.
Prestwich GD; Xu Y; Qian L; Gajewiak J; Jiang G
Biochem Soc Trans; 2005 Dec; 33(Pt 6):1357-61. PubMed ID: 16246118
[TBL] [Abstract][Full Text] [Related]
11. Concise synthesis of acyl migration-blocked 1,1-difluorinated analogues of lysophosphatidic acid.
Xu Y; Prestwich GD
J Org Chem; 2002 Oct; 67(20):7158-61. PubMed ID: 12354017
[TBL] [Abstract][Full Text] [Related]
12. Alkoxymethylenephosphonate analogues of (Lyso) phosphatidic acid stimulate signaling networks coupled to the LPA2 receptor.
Gajewiak J; Tsukahara R; Tsukahara T; Fujiwara Y; Yu S; Lu Y; Murph M; Mills GB; Tigyi G; Prestwich GD
ChemMedChem; 2007 Dec; 2(12):1789-98. PubMed ID: 17952880
[TBL] [Abstract][Full Text] [Related]
13. Structure--activity relationships of lysophosphatidic acid: conformationally restricted backbone mimetics.
Hopper DW; Ragan SP; Hooks SB; Lynch KR; Macdonald TL
J Med Chem; 1999 Mar; 42(6):963-70. PubMed ID: 10090779
[TBL] [Abstract][Full Text] [Related]
14. Alpha-substituted phosphonate analogues of lysophosphatidic acid (LPA) selectively inhibit production and action of LPA.
Jiang G; Xu Y; Fujiwara Y; Tsukahara T; Tsukahara R; Gajewiak J; Tigyi G; Prestwich GD
ChemMedChem; 2007 May; 2(5):679-90. PubMed ID: 17443831
[TBL] [Abstract][Full Text] [Related]
15. Structure-activity analysis of the effects of lysophosphatidic acid on platelet aggregation.
Gueguen G; Gaigé B; Grévy JM; Rogalle P; Bellan J; Wilson M; Klaébé A; Pont F; Simon MF; Chap H
Biochemistry; 1999 Jun; 38(26):8440-50. PubMed ID: 10387090
[TBL] [Abstract][Full Text] [Related]
16. Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of PPARgamma, and inhibitors of autotaxin.
Durgam GG; Virag T; Walker MD; Tsukahara R; Yasuda S; Liliom K; van Meeteren LA; Moolenaar WH; Wilke N; Siess W; Tigyi G; Miller DD
J Med Chem; 2005 Jul; 48(15):4919-30. PubMed ID: 16033271
[TBL] [Abstract][Full Text] [Related]
17. Synthesis, pharmacology, and cell biology of sn-2-aminooxy analogues of lysophosphatidic acid.
Gajewiak J; Tsukahara R; Fujiwara Y; Tigyi G; Prestwich GD
Org Lett; 2008 Mar; 10(6):1111-4. PubMed ID: 18284246
[TBL] [Abstract][Full Text] [Related]
18. LPA and its analogs-attractive tools for elucidation of LPA biology and drug development.
Kano K; Arima N; Ohgami M; Aoki J
Curr Med Chem; 2008; 15(21):2122-31. PubMed ID: 18781939
[TBL] [Abstract][Full Text] [Related]
19. Identification of residues responsible for ligand recognition and regioisomeric selectivity of lysophosphatidic acid receptors expressed in mammalian cells.
Fujiwara Y; Sardar V; Tokumura A; Baker D; Murakami-Murofushi K; Parrill A; Tigyi G
J Biol Chem; 2005 Oct; 280(41):35038-50. PubMed ID: 16115890
[TBL] [Abstract][Full Text] [Related]
20. Synthesis of alpha-fluorinated phosphonates from alpha-fluorovinylphosphonates: a new route to analogues of lysophosphatidic acid.
Xu Y; Qian L; Prestwich GD
Org Lett; 2003 Jun; 5(13):2267-70. PubMed ID: 12816425
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]