These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

992 related articles for article (PubMed ID: 15857888)

  • 1. Distinct transcriptional regulation and function of the human BACE2 and BACE1 genes.
    Sun X; Wang Y; Qing H; Christensen MA; Liu Y; Zhou W; Tong Y; Xiao C; Huang Y; Zhang S; Liu X; Song W
    FASEB J; 2005 May; 19(7):739-49. PubMed ID: 15857888
    [TBL] [Abstract][Full Text] [Related]  

  • 2. BACE2, as a novel APP theta-secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome.
    Sun X; He G; Song W
    FASEB J; 2006 Jul; 20(9):1369-76. PubMed ID: 16816112
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Control of APP processing and Abeta generation level by BACE1 enzymatic activity and transcription.
    Li Y; Zhou W; Tong Y; He G; Song W
    FASEB J; 2006 Feb; 20(2):285-92. PubMed ID: 16449801
    [TBL] [Abstract][Full Text] [Related]  

  • 5. BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein.
    Farzan M; Schnitzler CE; Vasilieva N; Leung D; Choe H
    Proc Natl Acad Sci U S A; 2000 Aug; 97(17):9712-7. PubMed ID: 10931940
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The proteins BACE1 and BACE2 and beta-secretase activity in normal and Alzheimer's disease brain.
    Stockley JH; O'Neill C
    Biochem Soc Trans; 2007 Jun; 35(Pt 3):574-6. PubMed ID: 17511655
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BACE2 degradation mediated by the macroautophagy-lysosome pathway.
    Liu X; Wang Z; Wu Y; Wang J; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1970-7. PubMed ID: 23773066
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional domains of the BACE1 and BACE2 promoters and mechanisms of transcriptional suppression of the BACE2 promoter in normal neuronal cells.
    Lahiri DK; Maloney B; Ge YW
    J Mol Neurosci; 2006; 29(1):65-80. PubMed ID: 16757811
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transcriptional and translational regulation of BACE1 expression--implications for Alzheimer's disease.
    Rossner S; Sastre M; Bourne K; Lichtenthaler SF
    Prog Neurobiol; 2006 Jun; 79(2):95-111. PubMed ID: 16904810
    [TBL] [Abstract][Full Text] [Related]  

  • 10. beta-Secretase, APP and Abeta in Alzheimer's disease.
    Vassar R
    Subcell Biochem; 2005; 38():79-103. PubMed ID: 15709474
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of peptides derived from BACE1 catalytic domain on APP processing.
    Yeon SW; Jeon YJ; Hwang EM; Kim TY
    Peptides; 2007 Apr; 28(4):838-44. PubMed ID: 17293005
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BACE1: the beta-secretase enzyme in Alzheimer's disease.
    Vassar R
    J Mol Neurosci; 2004; 23(1-2):105-14. PubMed ID: 15126696
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Protein expression of BACE1, BACE2 and APP in Down syndrome brains.
    Cheon MS; Dierssen M; Kim SH; Lubec G
    Amino Acids; 2008 Aug; 35(2):339-43. PubMed ID: 18163181
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The beta-secretase, BACE: a prime drug target for Alzheimer's disease.
    Vassar R
    J Mol Neurosci; 2001 Oct; 17(2):157-70. PubMed ID: 11816789
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cloning and expression of the rat BACE1 promoter.
    Lange-Dohna C; Zeitschel U; Gaunitz F; Perez-Polo JR; Bigl V; Rossner S
    J Neurosci Res; 2003 Jul; 73(1):73-80. PubMed ID: 12815710
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Swedish APP mutation alters the effect of genetically reduced BACE1 expression on the APP processing.
    Rabe S; Reichwald J; Ammaturo D; de Strooper B; Saftig P; Neumann U; Staufenbiel M
    J Neurochem; 2011 Oct; 119(1):231-9. PubMed ID: 21812781
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Decrease in brain soluble amyloid precursor protein β (sAPPβ) in Alzheimer's disease cortex.
    Wu G; Sankaranarayanan S; Hsieh SH; Simon AJ; Savage MJ
    J Neurosci Res; 2011 Jun; 89(6):822-32. PubMed ID: 21433051
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Early effects of aluminum chloride on beta-secretase mRNA expression in a neuronal model of beta-amyloid toxicity.
    Castorina A; Tiralongo A; Giunta S; Carnazza ML; Scapagnini G; D'Agata V
    Cell Biol Toxicol; 2010 Aug; 26(4):367-77. PubMed ID: 20111991
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BACE1 gene expression and protein degradation.
    Zhou W; Qing H; Tong Y; Song W
    Ann N Y Acad Sci; 2004 Dec; 1035():49-67. PubMed ID: 15681800
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Beta-secretase cleavage at amino acid residue 34 in the amyloid beta peptide is dependent upon gamma-secretase activity.
    Shi XP; Tugusheva K; Bruce JE; Lucka A; Wu GX; Chen-Dodson E; Price E; Li Y; Xu M; Huang Q; Sardana MK; Hazuda DJ
    J Biol Chem; 2003 Jun; 278(23):21286-94. PubMed ID: 12665519
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 50.