BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

227 related articles for article (PubMed ID: 15857955)

  • 1. An anchor site-type defect in human telomerase that disrupts telomere length maintenance and cellular immortalization.
    Moriarty TJ; Ward RJ; Taboski MA; Autexier C
    Mol Biol Cell; 2005 Jul; 16(7):3152-61. PubMed ID: 15857955
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A physical and functional constituent of telomerase anchor site.
    Lue NF
    J Biol Chem; 2005 Jul; 280(28):26586-91. PubMed ID: 15905172
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional organization of repeat addition processivity and DNA synthesis determinants in the human telomerase multimer.
    Moriarty TJ; Marie-Egyptienne DT; Autexier C
    Mol Cell Biol; 2004 May; 24(9):3720-33. PubMed ID: 15082768
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The C terminus of the human telomerase reverse transcriptase is a determinant of enzyme processivity.
    Huard S; Moriarty TJ; Autexier C
    Nucleic Acids Res; 2003 Jul; 31(14):4059-70. PubMed ID: 12853623
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human telomerase reverse transcriptase motifs required for elongation of a telomeric substrate.
    Lee SR; Wong JM; Collins K
    J Biol Chem; 2003 Dec; 278(52):52531-6. PubMed ID: 14565961
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A translocation-defective telomerase with low levels of activity and processivity stabilizes short telomeres and confers immortalization.
    D'Souza Y; Chu TW; Autexier C
    Mol Biol Cell; 2013 May; 24(9):1469-79. PubMed ID: 23447707
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A mutation in the catalytic subunit of yeast telomerase alters primer-template alignment while promoting processivity and protein-DNA binding.
    Bairley RC; Guillaume G; Vega LR; Friedman KL
    J Cell Sci; 2011 Dec; 124(Pt 24):4241-52. PubMed ID: 22193961
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Telomerase activity does not always imply telomere maintenance.
    Ouellette MM; Aisner DL; Savre-Train I; Wright WE; Shay JW
    Biochem Biophys Res Commun; 1999 Jan; 254(3):795-803. PubMed ID: 9920820
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutation in TERT separates processivity from anchor-site function.
    Zaug AJ; Podell ER; Cech TR
    Nat Struct Mol Biol; 2008 Aug; 15(8):870-2. PubMed ID: 18641663
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of 5' template usage and incorporation of noncognate nucleotides by human telomerase.
    Moriarty TJ; Marie-Egyptienne DT; Autexier C
    RNA; 2005 Sep; 11(9):1448-60. PubMed ID: 16120835
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of telomere length and homeostasis by telomerase enzyme processivity.
    D'Souza Y; Lauzon C; Chu TW; Autexier C
    J Cell Sci; 2013 Jan; 126(Pt 2):676-87. PubMed ID: 23178942
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human telomerase reverse transcriptase (hTERT) Q169 is essential for telomerase function in vitro and in vivo.
    Wyatt HD; Tsang AR; Lobb DA; Beattie TL
    PLoS One; 2009 Sep; 4(9):e7176. PubMed ID: 19777057
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of physical and functional anchor site interactions in human telomerase.
    Wyatt HD; Lobb DA; Beattie TL
    Mol Cell Biol; 2007 Apr; 27(8):3226-40. PubMed ID: 17296728
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modeling and structure function analysis of the putative anchor site of yeast telomerase.
    Lue NF; Li Z
    Nucleic Acids Res; 2007; 35(15):5213-22. PubMed ID: 17670795
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional multimerization of human telomerase requires an RNA interaction domain in the N terminus of the catalytic subunit.
    Moriarty TJ; Huard S; Dupuis S; Autexier C
    Mol Cell Biol; 2002 Feb; 22(4):1253-65. PubMed ID: 11809815
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A conserved telomerase motif within the catalytic domain of telomerase reverse transcriptase is specifically required for repeat addition processivity.
    Lue NF; Lin YC; Mian IS
    Mol Cell Biol; 2003 Dec; 23(23):8440-9. PubMed ID: 14612390
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel motif in telomerase reverse transcriptase regulates telomere repeat addition rate and processivity.
    Xie M; Podlevsky JD; Qi X; Bley CJ; Chen JJ
    Nucleic Acids Res; 2010 Apr; 38(6):1982-96. PubMed ID: 20044353
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The telomerase essential N-terminal domain promotes DNA synthesis by stabilizing short RNA-DNA hybrids.
    Akiyama BM; Parks JW; Stone MD
    Nucleic Acids Res; 2015 Jun; 43(11):5537-49. PubMed ID: 25940626
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domain.
    Middleman EJ; Choi J; Venteicher AS; Cheung P; Artandi SE
    Mol Cell Biol; 2006 Mar; 26(6):2146-59. PubMed ID: 16507993
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Processive utilization of the human telomerase template: lack of a requirement for template switching.
    Rivera MA; Blackburn EH
    J Biol Chem; 2004 Dec; 279(51):53770-81. PubMed ID: 15456773
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.