BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 15860657)

  • 1. Nicotine 5'-oxidation and methyl oxidation by P450 2A enzymes.
    Murphy SE; Raulinaitis V; Brown KM
    Drug Metab Dispos; 2005 Aug; 33(8):1166-73. PubMed ID: 15860657
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comparative metabolism of the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol by rat cytochrome P450 2A3 and human cytochrome P450 2A13.
    Jalas JR; Ding X; Murphy SE
    Drug Metab Dispos; 2003 Oct; 31(10):1199-202. PubMed ID: 12975327
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-butanone metabolism by cytochrome P450 2B6.
    Dicke KE; Skrlin SM; Murphy SE
    Drug Metab Dispos; 2005 Dec; 33(12):1760-4. PubMed ID: 16174803
    [TBL] [Abstract][Full Text] [Related]  

  • 4. N-Nitrosobenzylmethylamine hydroxylation and coumarin 7-hydroxylation: catalysis by rat esophageal microsomes and cytochrome P450 2A3 and 2A6 enzymes.
    von Weymarn LB; Felicia ND; Ding X; Murphy SE
    Chem Res Toxicol; 1999 Dec; 12(12):1254-61. PubMed ID: 10604876
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of N-(hydroxymethyl) norcotinine as a major product of cytochrome P450 2A6, but not cytochrome P450 2A13-catalyzed cotinine metabolism.
    Brown KM; von Weymarn LB; Murphy SE
    Chem Res Toxicol; 2005 Dec; 18(12):1792-8. PubMed ID: 16359169
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evidence for cytochrome P450 2A6 and 3A4 as major catalysts for N'-nitrosonornicotine alpha-hydroxylation by human liver microsomes.
    Patten CJ; Smith TJ; Friesen MJ; Tynes RE; Yang CS; Murphy SE
    Carcinogenesis; 1997 Aug; 18(8):1623-30. PubMed ID: 9276639
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cytochrome P450 2A-catalyzed metabolic activation of structurally similar carcinogenic nitrosamines: N'-nitrosonornicotine enantiomers, N-nitrosopiperidine, and N-nitrosopyrrolidine.
    Wong HL; Murphy SE; Hecht SS
    Chem Res Toxicol; 2005 Jan; 18(1):61-9. PubMed ID: 15651850
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of multiple products of cytochrome P450 2A6-catalyzed cotinine metabolism.
    Murphy SE; Johnson LM; Pullo DA
    Chem Res Toxicol; 1999 Jul; 12(7):639-45. PubMed ID: 10409404
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of human liver microsomal (S)-nicotine oxidation by (-)-menthol and analogues.
    MacDougall JM; Fandrick K; Zhang X; Serafin SV; Cashman JR
    Chem Res Toxicol; 2003 Aug; 16(8):988-93. PubMed ID: 12924926
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabolism of nicotine and cotinine by human cytochrome P450 2A13.
    Bao Z; He XY; Ding X; Prabhu S; Hong JY
    Drug Metab Dispos; 2005 Feb; 33(2):258-61. PubMed ID: 15528319
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of cytochrome P450 2A4 and 2A5-catalyzed 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism.
    Felicia ND; Rekha GK; Murphy SE
    Arch Biochem Biophys; 2000 Dec; 384(2):418-24. PubMed ID: 11368333
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A major role for CYP2A6 in nicotine C-oxidation by human liver microsomes.
    Messina ES; Tyndale RF; Sellers EM
    J Pharmacol Exp Ther; 1997 Sep; 282(3):1608-14. PubMed ID: 9316878
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inactivation of CYP2A6 and CYP2A13 during nicotine metabolism.
    von Weymarn LB; Brown KM; Murphy SE
    J Pharmacol Exp Ther; 2006 Jan; 316(1):295-303. PubMed ID: 16188955
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Specificity of cytochrome P450 2A3-catalyzed alpha-hydroxylation of N'-nitrosonornicotine enantiomers.
    Murphy SE; Isaac IS; Ding X; McIntee EJ
    Drug Metab Dispos; 2000 Nov; 28(11):1263-6. PubMed ID: 11038149
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Comparative metabolism of N-nitrosopiperidine and N-nitrosopyrrolidine by rat liver and esophageal microsomes and cytochrome P450 2A3.
    Wong HL; Murphy SE; Wang M; Hecht SS
    Carcinogenesis; 2003 Feb; 24(2):291-300. PubMed ID: 12584180
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of human cytochrome P4502A6 in C-oxidation of nicotine.
    Nakajima M; Yamamoto T; Nunoya K; Yokoi T; Nagashima K; Inoue K; Funae Y; Shimada N; Kamataki T; Kuroiwa Y
    Drug Metab Dispos; 1996 Nov; 24(11):1212-7. PubMed ID: 8937855
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 2'-Hydroxylation of nicotine by cytochrome P450 2A6 and human liver microsomes: formation of a lung carcinogen precursor.
    Hecht SS; Hochalter JB; Villalta PW; Murphy SE
    Proc Natl Acad Sci U S A; 2000 Nov; 97(23):12493-7. PubMed ID: 11050152
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Preferential metabolic activation of N-nitrosopiperidine as compared to its structural homologue N-nitrosopyrrolidine by rat nasal mucosal microsomes.
    Wong HL; Murphy SE; Hecht SS
    Chem Res Toxicol; 2003 Oct; 16(10):1298-305. PubMed ID: 14565771
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vitro-in vivo correlations of human (S)-nicotine metabolism.
    Berkman CE; Park SB; Wrighton SA; Cashman JR
    Biochem Pharmacol; 1995 Aug; 50(4):565-70. PubMed ID: 7646564
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CYP2A6- and CYP2A13-catalyzed metabolism of the nicotine Δ5'(1')iminium ion.
    von Weymarn LB; Retzlaff C; Murphy SE
    J Pharmacol Exp Ther; 2012 Nov; 343(2):307-15. PubMed ID: 22869927
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.