BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 15862969)

  • 1. The effects of 2-methoxyoestrogen sulphamates on the in vitro and in vivo proliferation of breast cancer cells.
    Utsumi T; Leese MP; Chander SK; Gaukroger K; Purohit A; Newman SP; Potter BV; Reed MJ
    J Steroid Biochem Mol Biol; 2005 Feb; 94(1-3):219-27. PubMed ID: 15862969
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of estrone sulfatase and proliferation of human breast cancer cells by nonsteroidal (p-O-sulfamoyl)-N-alkanoyl tyramines.
    Selcer KW; Hegde PV; Li PK
    Cancer Res; 1997 Feb; 57(4):702-7. PubMed ID: 9044848
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vivo efficacy of STX213, a second-generation steroid sulfatase inhibitor, for hormone-dependent breast cancer therapy.
    Foster PA; Newman SP; Chander SK; Stengel C; Jhalli R; Woo LL; Potter BV; Reed MJ; Purohit A
    Clin Cancer Res; 2006 Sep; 12(18):5543-9. PubMed ID: 17000691
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of MCF-7 breast cancer cell proliferation and in vivo steroid sulphatase activity by 2-methoxyoestradiol-bis-sulphamate.
    Raobaikady B; Purohit A; Chander SK; Woo LW; Leese MP; Potter BV; Reed MJ
    J Steroid Biochem Mol Biol; 2003 Feb; 84(2-3):351-8. PubMed ID: 12711022
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development of novel steroid sulfatase inhibitors; II. TZS-8478 potently inhibits the growth of breast tumors in postmenopausal breast cancer model rats.
    Saito T; Kinoshita S; Fujii T; Bandoh K; Fuse S; Yamauchi Y; Koizumi N; Horiuchi T
    J Steroid Biochem Mol Biol; 2004 Feb; 88(2):167-73. PubMed ID: 15084348
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A-ring-substituted estrogen-3-O-sulfamates: potent multitargeted anticancer agents.
    Leese MP; Hejaz HA; Mahon MF; Newman SP; Purohit A; Reed MJ; Potter BV
    J Med Chem; 2005 Aug; 48(16):5243-56. PubMed ID: 16078843
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Efficacy of three potent steroid sulfatase inhibitors: pre-clinical investigations for their use in the treatment of hormone-dependent breast cancer.
    Foster PA; Chander SK; Parsons MF; Newman SP; Woo LW; Potter BV; Reed MJ; Purohit A
    Breast Cancer Res Treat; 2008 Sep; 111(1):129-38. PubMed ID: 17914670
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 2-phenylindole sulfamates: inhibitors of steroid sulfatase with antiproliferative activity in MCF-7 breast cancer cells.
    Walter G; Liebl R; von Angerer E
    J Steroid Biochem Mol Biol; 2004 Apr; 88(4-5):409-20. PubMed ID: 15145451
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Estradiol and estrone C-16 derivatives as inhibitors of type 1 17beta-hydroxysteroid dehydrogenase: blocking of ER+ breast cancer cell proliferation induced by estrone.
    Laplante Y; Cadot C; Fournier MA; Poirier D
    Bioorg Med Chem; 2008 Feb; 16(4):1849-60. PubMed ID: 18035543
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A new therapeutic strategy against hormone-dependent breast cancer: the preclinical development of a dual aromatase and sulfatase inhibitor.
    Foster PA; Chander SK; Newman SP; Woo LW; Sutcliffe OB; Bubert C; Zhou D; Chen S; Potter BV; Reed MJ; Purohit A
    Clin Cancer Res; 2008 Oct; 14(20):6469-77. PubMed ID: 18927286
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel steroidal selective steroid sulfatase inhibitor KW-2581 inhibits sulfated-estrogen dependent growth of breast cancer cells in vitro and in animal models.
    Ishida H; Nakata T; Suzuki M; Shiotsu Y; Tanaka H; Sato N; Terasaki Y; Takebayashi M; Anazawa H; Murakata C; Li PK; Kuwabara T; Akinaga S
    Breast Cancer Res Treat; 2007 Dec; 106(2):215-27. PubMed ID: 17268815
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The nature of inhibition of steroid sulphatase activity by tibolone and its metabolites.
    Raobaikady B; Day JM; Purohit A; Potter BV; Reed MJ
    J Steroid Biochem Mol Biol; 2005 Feb; 94(1-3):229-37. PubMed ID: 15862970
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 2-MeOE2bisMATE and 2-EtE2bisMATE induce cell cycle arrest and apoptosis in breast cancer xenografts as shown by a novel ex vivo technique.
    Foster PA; Ho YT; Newman SP; Kasprzyk PG; Leese MP; Potter BV; Reed MJ; Purohit A
    Breast Cancer Res Treat; 2008 Sep; 111(2):251-60. PubMed ID: 17957467
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Anti-cancer activities of novel D-ring modified 2-substituted estrogen-3-O-sulfamates.
    Leese MP; Leblond B; Newman SP; Purohit A; Reed MJ; Potter BV
    J Steroid Biochem Mol Biol; 2005 Feb; 94(1-3):239-51. PubMed ID: 15862971
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of steroid sulfatase activity and cell proliferation in ZR-75-1 and BT-474 human breast cancer cells by KW-2581 in vitro and in vivo.
    Ishida H; Nakata T; Sato N; Li PK; Kuwabara T; Akinaga S
    Breast Cancer Res Treat; 2007 Aug; 104(2):211-9. PubMed ID: 17061037
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of steroid sulphatase activity via the percutaneous route: a new option for breast cancer therapy.
    Purohit A; Chander SK; Woo LW; Parsons MF; Jhalli R; Potter BV; Reed MJ
    Anticancer Res; 2008; 28(3A):1517-23. PubMed ID: 18630506
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, in vitro and in vivo activity of benzophenone-based inhibitors of steroid sulfatase.
    Hejaz HA; Woo LW; Purohit A; Reed MJ; Potter BV
    Bioorg Med Chem; 2004 May; 12(10):2759-72. PubMed ID: 15110857
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of oestrone sulphatase activity by tibolone and its metabolites.
    Purohit A; Malini B; Hooymans C; Newman SP
    Horm Metab Res; 2002 Jan; 34(1):1-6. PubMed ID: 11832993
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological activity of the superestrogen (E)-17-oximino-3-O-sulfamoyl-1,3,5(10)-estratriene: x-ray crystal structure of (E)-17-oximino-3-hydroxy-1,3,5(10)-estratriene.
    Hejaz HA; Purohit A; Mahon MF; Reed MJ; Potter BV
    J Med Chem; 1999 Aug; 42(16):3188-92. PubMed ID: 10447965
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity.
    Leese MP; Leblond B; Smith A; Newman SP; Di Fiore A; De Simone G; Supuran CT; Purohit A; Reed MJ; Potter BV
    J Med Chem; 2006 Dec; 49(26):7683-96. PubMed ID: 17181151
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.