BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 15865427)

  • 1. Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2.
    Radisky ES; Lu CJ; Kwan G; Koshland DE
    Biochemistry; 2005 May; 44(18):6823-30. PubMed ID: 15865427
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Binding, proteolytic, and crystallographic analyses of mutations at the protease-inhibitor interface of the subtilisin BPN'/chymotrypsin inhibitor 2 complex.
    Radisky ES; Kwan G; Karen Lu CJ; Koshland DE
    Biochemistry; 2004 Nov; 43(43):13648-56. PubMed ID: 15504027
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The role of the protein core in the inhibitory power of the classic serine protease inhibitor, chymotrypsin inhibitor 2.
    Radisky ES; King DS; Kwan G; Koshland DE
    Biochemistry; 2003 Jun; 42(21):6484-92. PubMed ID: 12767231
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural and biochemical studies of inhibitor binding to human cytomegalovirus protease.
    Khayat R; Batra R; Qian C; Halmos T; Bailey M; Tong L
    Biochemistry; 2003 Feb; 42(4):885-91. PubMed ID: 12549906
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Recombinant chymotrypsin inhibitor 2: expression, kinetic analysis of inhibition with alpha-chymotrypsin and wild-type and mutant subtilisin BPN', and protein engineering to investigate inhibitory specificity and mechanism.
    Longstaff C; Campbell AF; Fersht AR
    Biochemistry; 1990 Aug; 29(31):7339-47. PubMed ID: 2207109
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I.
    Bateman KS; Huang K; Anderson S; Lu W; Qasim MA; Laskowski M; James MN
    J Mol Biol; 2001 Jan; 305(4):839-49. PubMed ID: 11162096
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Engineering of the pH optimum of Bacillus cereus beta-amylase: conversion of the pH optimum from a bacterial type to a higher-plant type.
    Hirata A; Adachi M; Utsumi S; Mikami B
    Biochemistry; 2004 Oct; 43(39):12523-31. PubMed ID: 15449941
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Changing the inhibitory specificity and function of the proteinase inhibitor eglin c by site-directed mutagenesis: functional and structural investigation.
    Heinz DW; Hyberts SG; Peng JW; Priestle JP; Wagner G; Grütter MG
    Biochemistry; 1992 Sep; 31(37):8755-66. PubMed ID: 1390662
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Contribution of residues in the reactive site loop of chymotrypsin inhibitor 2 to protein stability and activity.
    Jackson SE; Fersht AR
    Biochemistry; 1994 Nov; 33(46):13880-7. PubMed ID: 7947796
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stabilized variant of Streptomyces subtilisin inhibitor and its use in stabilizing subtilisin BPN'.
    Ganz PJ; Bauer MD; Sun Y; Fieno AM; Grant RA; Correa PE; Laskowski M; Saunders CW
    Protein Eng Des Sel; 2004 Apr; 17(4):333-9. PubMed ID: 15187224
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
    Stoll VS; Eger BT; Hynes RC; Martichonok V; Jones JB; Pai EF
    Biochemistry; 1998 Jan; 37(2):451-62. PubMed ID: 9425066
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Solution studies of chymotrypsin inhibitor-2 glutamine insertion mutants show no interglutamine interactions.
    Gordon-Smith DJ; Carbajo RJ; Stott K; Neuhaus D
    Biochem Biophys Res Commun; 2001 Jan; 280(3):855-60. PubMed ID: 11162601
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The structural basis of a conserved P2 threonine in canonical serine proteinase inhibitors.
    Brauer AB; Nievo M; McBride JD; Leatherbarrow RJ
    J Biomol Struct Dyn; 2003 Apr; 20(5):645-56. PubMed ID: 12643767
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The 0.78 A structure of a serine protease: Bacillus lentus subtilisin.
    Kuhn P; Knapp M; Soltis SM; Ganshaw G; Thoene M; Bott R
    Biochemistry; 1998 Sep; 37(39):13446-52. PubMed ID: 9753430
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kinetics of factor Xa inhibition by recombinant tick anticoagulant peptide: both active site and exosite interactions are required for a slow- and tight-binding inhibition mechanism.
    Rezaie AR
    Biochemistry; 2004 Mar; 43(12):3368-75. PubMed ID: 15035608
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Intramolecular orbital alignments in serine protease/protein inhibitor complexes.
    Fan YH; Grégoire CA; Haseltine J
    Bioorg Med Chem; 2004 Jun; 12(11):3097-106. PubMed ID: 15142568
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural and dynamic changes in human annexin VI induced by a phosphorylation-mimicking mutation, T356D.
    Freye-Minks C; Kretsinger RH; Creutz CE
    Biochemistry; 2003 Jan; 42(3):620-30. PubMed ID: 12534274
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Spacer Asn determines the fate of Kunitz (STI) inhibitors, as revealed by structural and biochemical studies on WCI mutants.
    Dasgupta J; Khamrui S; Dattagupta JK; Sen U
    Biochemistry; 2006 Jun; 45(22):6783-92. PubMed ID: 16734415
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Variable contributions of tyrosine residues to the structural and spectroscopic properties of the factor for inversion stimulation.
    Boswell S; Mathew J; Beach M; Osuna R; Colón W
    Biochemistry; 2004 Mar; 43(10):2964-77. PubMed ID: 15005633
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Active site binding loop stabilization in the subtilisin inhibitor eglin c: structural and functional studies on specifically designed mutants in complex with subtilisin and the uncomplexed inhibitor.
    Hipler K; Priestle JP; Rahuel J; Grütter MG
    Adv Exp Med Biol; 1996; 379():43-7. PubMed ID: 8796309
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.