321 related articles for article (PubMed ID: 15878852)
1. Rheb binding to mammalian target of rapamycin (mTOR) is regulated by amino acid sufficiency.
Long X; Ortiz-Vega S; Lin Y; Avruch J
J Biol Chem; 2005 Jun; 280(25):23433-6. PubMed ID: 15878852
[TBL] [Abstract][Full Text] [Related]
2. The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses.
Smith EM; Finn SG; Tee AR; Browne GJ; Proud CG
J Biol Chem; 2005 May; 280(19):18717-27. PubMed ID: 15772076
[TBL] [Abstract][Full Text] [Related]
3. Rheb binds and regulates the mTOR kinase.
Long X; Lin Y; Ortiz-Vega S; Yonezawa K; Avruch J
Curr Biol; 2005 Apr; 15(8):702-13. PubMed ID: 15854902
[TBL] [Abstract][Full Text] [Related]
4. Amino acid regulation of TOR complex 1.
Avruch J; Long X; Ortiz-Vega S; Rapley J; Papageorgiou A; Dai N
Am J Physiol Endocrinol Metab; 2009 Apr; 296(4):E592-602. PubMed ID: 18765678
[TBL] [Abstract][Full Text] [Related]
5. Rheb activates mTOR by antagonizing its endogenous inhibitor, FKBP38.
Bai X; Ma D; Liu A; Shen X; Wang QJ; Liu Y; Jiang Y
Science; 2007 Nov; 318(5852):977-80. PubMed ID: 17991864
[TBL] [Abstract][Full Text] [Related]
6. Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging.
Oshiro N; Rapley J; Avruch J
J Biol Chem; 2014 Jan; 289(5):2658-74. PubMed ID: 24337580
[TBL] [Abstract][Full Text] [Related]
7. The Rheb switch 2 segment is critical for signaling to target of rapamycin complex 1.
Long X; Lin Y; Ortiz-Vega S; Busch S; Avruch J
J Biol Chem; 2007 Jun; 282(25):18542-18551. PubMed ID: 17470430
[TBL] [Abstract][Full Text] [Related]
8. Molecular mechanisms through which amino acids mediate signaling through the mammalian target of rapamycin.
Kimball SR; Jefferson LS
Curr Opin Clin Nutr Metab Care; 2004 Jan; 7(1):39-44. PubMed ID: 15090902
[TBL] [Abstract][Full Text] [Related]
9. Re-evaluating the roles of proposed modulators of mammalian target of rapamycin complex 1 (mTORC1) signaling.
Wang X; Fonseca BD; Tang H; Liu R; Elia A; Clemens MJ; Bommer UA; Proud CG
J Biol Chem; 2008 Nov; 283(45):30482-92. PubMed ID: 18676370
[TBL] [Abstract][Full Text] [Related]
10. Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent.
Karbowniczek M; Cash T; Cheung M; Robertson GP; Astrinidis A; Henske EP
J Biol Chem; 2004 Jul; 279(29):29930-7. PubMed ID: 15150271
[TBL] [Abstract][Full Text] [Related]
11. The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1.
Oshiro N; Takahashi R; Yoshino K; Tanimura K; Nakashima A; Eguchi S; Miyamoto T; Hara K; Takehana K; Avruch J; Kikkawa U; Yonezawa K
J Biol Chem; 2007 Jul; 282(28):20329-39. PubMed ID: 17517883
[TBL] [Abstract][Full Text] [Related]
12. Phospholipase D1 is an effector of Rheb in the mTOR pathway.
Sun Y; Fang Y; Yoon MS; Zhang C; Roccio M; Zwartkruis FJ; Armstrong M; Brown HA; Chen J
Proc Natl Acad Sci U S A; 2008 Jun; 105(24):8286-91. PubMed ID: 18550814
[TBL] [Abstract][Full Text] [Related]
13. Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb.
Lee MN; Ha SH; Kim J; Koh A; Lee CS; Kim JH; Jeon H; Kim DH; Suh PG; Ryu SH
Mol Cell Biol; 2009 Jul; 29(14):3991-4001. PubMed ID: 19451232
[TBL] [Abstract][Full Text] [Related]
14. The farnesyl transferase inhibitor (FTI) SCH66336 (lonafarnib) inhibits Rheb farnesylation and mTOR signaling. Role in FTI enhancement of taxane and tamoxifen anti-tumor activity.
Basso AD; Mirza A; Liu G; Long BJ; Bishop WR; Kirschmeier P
J Biol Chem; 2005 Sep; 280(35):31101-8. PubMed ID: 16006564
[TBL] [Abstract][Full Text] [Related]
15. Follicle-stimulating hormone activation of hypoxia-inducible factor-1 by the phosphatidylinositol 3-kinase/AKT/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is necessary for induction of select protein markers of follicular differentiation.
Alam H; Maizels ET; Park Y; Ghaey S; Feiger ZJ; Chandel NS; Hunzicker-Dunn M
J Biol Chem; 2004 May; 279(19):19431-40. PubMed ID: 14982927
[TBL] [Abstract][Full Text] [Related]
16. Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner.
Castro AF; Rebhun JF; Clark GJ; Quilliam LA
J Biol Chem; 2003 Aug; 278(35):32493-6. PubMed ID: 12842888
[TBL] [Abstract][Full Text] [Related]
17. Insulin and amino-acid regulation of mTOR signaling and kinase activity through the Rheb GTPase.
Avruch J; Hara K; Lin Y; Liu M; Long X; Ortiz-Vega S; Yonezawa K
Oncogene; 2006 Oct; 25(48):6361-72. PubMed ID: 17041622
[TBL] [Abstract][Full Text] [Related]
18. Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb.
Li Y; Wang Y; Kim E; Beemiller P; Wang CY; Swanson J; You M; Guan KL
J Biol Chem; 2007 Dec; 282(49):35803-13. PubMed ID: 17928295
[TBL] [Abstract][Full Text] [Related]
19. Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity.
Li Y; Inoki K; Guan KL
Mol Cell Biol; 2004 Sep; 24(18):7965-75. PubMed ID: 15340059
[TBL] [Abstract][Full Text] [Related]
20. mTOR direct interactions with Rheb-GTPase and raptor: sub-cellular localization using fluorescence lifetime imaging.
Yadav RB; Burgos P; Parker AW; Iadevaia V; Proud CG; Allen RA; O'Connell JP; Jeshtadi A; Stubbs CD; Botchway SW
BMC Cell Biol; 2013 Jan; 14():3. PubMed ID: 23311891
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]