BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

556 related articles for article (PubMed ID: 15888547)

  • 1. Role of SHPS-1 in the regulation of insulin-like growth factor I-stimulated Shc and mitogen-activated protein kinase activation in vascular smooth muscle cells.
    Ling Y; Maile LA; Lieskovska J; Badley-Clarke J; Clemmons DR
    Mol Biol Cell; 2005 Jul; 16(7):3353-64. PubMed ID: 15888547
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The role of Src kinase in insulin-like growth factor-dependent mitogenic signaling in vascular smooth muscle cells.
    Lieskovska J; Ling Y; Badley-Clarke J; Clemmons DR
    J Biol Chem; 2006 Sep; 281(35):25041-53. PubMed ID: 16825188
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insulin-like growth factor-I-stimulated insulin receptor substrate-1 negatively regulates Src homology 2 domain-containing protein-tyrosine phosphatase substrate-1 function in vascular smooth muscle cells.
    Radhakrishnan Y; Busby WH; Shen X; Maile LA; Clemmons DR
    J Biol Chem; 2010 May; 285(21):15682-95. PubMed ID: 20207740
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The association between integrin-associated protein and SHPS-1 regulates insulin-like growth factor-I receptor signaling in vascular smooth muscle cells.
    Maile LA; Badley-Clarke J; Clemmons DR
    Mol Biol Cell; 2003 Sep; 14(9):3519-28. PubMed ID: 12972543
    [TBL] [Abstract][Full Text] [Related]  

  • 5. p66shc negatively regulates insulin-like growth factor I signal transduction via inhibition of p52shc binding to Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 leading to impaired growth factor receptor-bound protein-2 membrane recruitment.
    Xi G; Shen X; Clemmons DR
    Mol Endocrinol; 2008 Sep; 22(9):2162-75. PubMed ID: 18606861
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cells.
    Radhakrishnan Y; Maile LA; Ling Y; Graves LM; Clemmons DR
    J Biol Chem; 2008 Jun; 283(24):16320-31. PubMed ID: 18420583
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression of the human beta3 integrin subunit in mouse smooth muscle cells enhances IGF-I-stimulated signaling and proliferation.
    Xi G; Maile LA; Yoo SE; Clemmons DR
    J Cell Physiol; 2008 Feb; 214(2):306-15. PubMed ID: 17607710
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interaction between insulin-like growth factor-I receptor and alphaVbeta3 integrin linked signaling pathways: cellular responses to changes in multiple signaling inputs.
    Clemmons DR; Maile LA
    Mol Endocrinol; 2005 Jan; 19(1):1-11. PubMed ID: 15528274
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Recruitment of the tyrosine phosphatase Src homology 2 domain tyrosine phosphatase-2 to the p85 subunit of phosphatidylinositol-3 (PI-3) kinase is required for insulin-like growth factor-I-dependent PI-3 kinase activation in smooth muscle cells.
    Kwon M; Ling Y; Maile LA; Badley-Clark J; Clemmons DR
    Endocrinology; 2006 Mar; 147(3):1458-65. PubMed ID: 16306077
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DOK1 mediates SHP-2 binding to the alphaVbeta3 integrin and thereby regulates insulin-like growth factor I signaling in cultured vascular smooth muscle cells.
    Ling Y; Maile LA; Badley-Clarke J; Clemmons DR
    J Biol Chem; 2005 Feb; 280(5):3151-8. PubMed ID: 15546884
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of novel SHPS-1-associated proteins and their roles in regulation of insulin-like growth factor-dependent responses in vascular smooth muscle cells.
    Shen X; Xi G; Radhakrishnan Y; Clemmons DR
    Mol Cell Proteomics; 2009 Jul; 8(7):1539-51. PubMed ID: 19299420
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of igf-I signaling in retinal endothelial cells by hyperglycemia.
    Miller EC; Capps BE; Sanghani RR; Clemmons DR; Maile LA
    Invest Ophthalmol Vis Sci; 2007 Aug; 48(8):3878-87. PubMed ID: 17652764
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanism of SHIP-mediated inhibition of insulin- and platelet-derived growth factor-stimulated mitogen-activated protein kinase activity in 3T3-L1 adipocytes.
    Sharma PM; Son HS; Ugi S; Ricketts W; Olefsky JM
    Mol Endocrinol; 2005 Feb; 19(2):421-30. PubMed ID: 15486046
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PDK1 recruitment to the SHPS-1 signaling complex enhances insulin-like growth factor-i-stimulated AKT activation and vascular smooth muscle cell survival.
    Shen X; Xi G; Radhakrishnan Y; Clemmons DR
    J Biol Chem; 2010 Sep; 285(38):29416-24. PubMed ID: 20643654
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tyrosine phosphorylation of the beta3-subunit of the alphaVbeta3 integrin is required for embrane association of the tyrosine phosphatase SHP-2 and its further recruitment to the insulin-like growth factor I receptor.
    Ling Y; Maile LA; Clemmons DR
    Mol Endocrinol; 2003 Sep; 17(9):1824-33. PubMed ID: 12791772
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The alphaVbeta3 integrin regulates insulin-like growth factor I (IGF-I) receptor phosphorylation by altering the rate of recruitment of the Src-homology 2-containing phosphotyrosine phosphatase-2 to the activated IGF-I receptor.
    Maile LA; Clemmons DR
    Endocrinology; 2002 Nov; 143(11):4259-64. PubMed ID: 12399420
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Flt3 signaling involves tyrosyl-phosphorylation of SHP-2 and SHIP and their association with Grb2 and Shc in Baf3/Flt3 cells.
    Zhang S; Mantel C; Broxmeyer HE
    J Leukoc Biol; 1999 Mar; 65(3):372-80. PubMed ID: 10080542
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Recruitment of Pyk2 to SHPS-1 signaling complex is required for IGF-I-dependent mitogenic signaling in vascular smooth muscle cells.
    Shen X; Xi G; Radhakrishnan Y; Clemmons DR
    Cell Mol Life Sci; 2010 Nov; 67(22):3893-903. PubMed ID: 20521079
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of insulin-like growth factor I receptor dephosphorylation by SHPS-1 and the tyrosine phosphatase SHP-2.
    Maile LA; Clemmons DR
    J Biol Chem; 2002 Mar; 277(11):8955-60. PubMed ID: 11779860
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Increased insulin sensitivity in IGF-I receptor--deficient brown adipocytes.
    Mur C; Valverde AM; Kahn CR; Benito M
    Diabetes; 2002 Mar; 51(3):743-54. PubMed ID: 11872675
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.