These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
221 related articles for article (PubMed ID: 15892251)
1. Maximizing discovery efficiency with a computationally driven fragment approach. Moore WR Curr Opin Drug Discov Devel; 2005 May; 8(3):355-64. PubMed ID: 15892251 [TBL] [Abstract][Full Text] [Related]
2. Informatics and modeling challenges in fragment-based drug discovery. Hubbard RE; Chen I; Davis B Curr Opin Drug Discov Devel; 2007 May; 10(3):289-97. PubMed ID: 17554855 [TBL] [Abstract][Full Text] [Related]
3. New approaches to drug discovery and development: a mechanism-based approach to pharmaceutical research and its application to BNP7787, a novel chemoprotective agent. Hausheer FH; Kochat H; Parker AR; Ding D; Yao S; Hamilton SE; Petluru PN; Leverett BD; Bain SH; Saxe JD Cancer Chemother Pharmacol; 2003 Jul; 52 Suppl 1():S3-15. PubMed ID: 12819940 [TBL] [Abstract][Full Text] [Related]
5. Lead optimization via high-throughput molecular docking. Joseph-McCarthy D; Baber JC; Feyfant E; Thompson DC; Humblet C Curr Opin Drug Discov Devel; 2007 May; 10(3):264-74. PubMed ID: 17554852 [TBL] [Abstract][Full Text] [Related]
6. A rational approach to maximize success rate in target discovery. Schneider M Arch Pharm (Weinheim); 2004 Dec; 337(12):625-33. PubMed ID: 15597396 [TBL] [Abstract][Full Text] [Related]
7. Computational chemistry approaches to drug discovery in signal transduction. Fischer PM Biotechnol J; 2008 Apr; 3(4):452-70. PubMed ID: 18412174 [TBL] [Abstract][Full Text] [Related]
8. Fragment analysis in small molecule discovery. Merlot C; Domine D; Church DJ Curr Opin Drug Discov Devel; 2002 May; 5(3):391-9. PubMed ID: 12058614 [TBL] [Abstract][Full Text] [Related]
9. G-protein-coupled receptor-focused drug discovery using a target class platform approach. Heilker R; Wolff M; Tautermann CS; Bieler M Drug Discov Today; 2009 Mar; 14(5-6):231-40. PubMed ID: 19121411 [TBL] [Abstract][Full Text] [Related]
10. A scalable approach to combinatorial library design for drug discovery. Sharma P; Salapaka S; Beck C J Chem Inf Model; 2008 Jan; 48(1):27-41. PubMed ID: 18052333 [TBL] [Abstract][Full Text] [Related]
11. The synergy between combinatorial chemistry and high-throughput screening. Diller DJ Curr Opin Drug Discov Devel; 2008 May; 11(3):346-55. PubMed ID: 18428088 [TBL] [Abstract][Full Text] [Related]
12. [Development of antituberculous drugs: current status and future prospects]. Tomioka H; Namba K Kekkaku; 2006 Dec; 81(12):753-74. PubMed ID: 17240921 [TBL] [Abstract][Full Text] [Related]
13. Fragment-based lead discovery: a chemical update. Erlanson DA Curr Opin Biotechnol; 2006 Dec; 17(6):643-52. PubMed ID: 17084612 [TBL] [Abstract][Full Text] [Related]
14. The use of chemical design tools to transform proteomics data into drug candidates. Dean PM; Zanders ED Biotechniques; 2002 Mar; Suppl():28-33. PubMed ID: 11906004 [TBL] [Abstract][Full Text] [Related]
16. Strategies and tactics for optimizing the Hit-to-Lead process and beyond--a computational chemistry perspective. Manly CJ; Chandrasekhar J; Ochterski JW; Hammer JD; Warfield BB Drug Discov Today; 2008 Feb; 13(3-4):99-109. PubMed ID: 18275907 [TBL] [Abstract][Full Text] [Related]
17. Molecular modeling of hydration in drug design. Mancera RL Curr Opin Drug Discov Devel; 2007 May; 10(3):275-80. PubMed ID: 17554853 [TBL] [Abstract][Full Text] [Related]
18. Characterization of protein-ligand interaction sites using experimental and computational methods. Vajda S; Guarnieri F Curr Opin Drug Discov Devel; 2006 May; 9(3):354-62. PubMed ID: 16729732 [TBL] [Abstract][Full Text] [Related]
19. Integrating molecular design resources within modern drug discovery research: the Roche experience. Stahl M; Guba W; Kansy M Drug Discov Today; 2006 Apr; 11(7-8):326-33. PubMed ID: 16580974 [TBL] [Abstract][Full Text] [Related]
20. Computation of the physio-chemical properties and data mining of large molecular collections. Cheng A; Diller DJ; Dixon SL; Egan WJ; Lauri G; Merz KM J Comput Chem; 2002 Jan; 23(1):172-83. PubMed ID: 11913384 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]