340 related articles for article (PubMed ID: 15893541)
1. Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal human bronchial epithelial cells through NFkappaB activation and cyclin D1 up-regulation.
Ho YS; Chen CH; Wang YJ; Pestell RG; Albanese C; Chen RJ; Chang MC; Jeng JH; Lin SY; Liang YC; Tseng H; Lee WS; Lin JK; Chu JS; Chen LC; Lee CH; Tso WL; Lai YC; Wu CH
Toxicol Appl Pharmacol; 2005 Jun; 205(2):133-48. PubMed ID: 15893541
[TBL] [Abstract][Full Text] [Related]
2. Tobacco components stimulate Akt-dependent proliferation and NFkappaB-dependent survival in lung cancer cells.
Tsurutani J; Castillo SS; Brognard J; Granville CA; Zhang C; Gills JJ; Sayyah J; Dennis PA
Carcinogenesis; 2005 Jul; 26(7):1182-95. PubMed ID: 15790591
[TBL] [Abstract][Full Text] [Related]
3. Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induce cyclooxygenase-2 activity in human gastric cancer cells: Involvement of nicotinic acetylcholine receptor (nAChR) and beta-adrenergic receptor signaling pathways.
Shin VY; Jin HC; Ng EK; Yu J; Leung WK; Cho CH; Sung JJ
Toxicol Appl Pharmacol; 2008 Dec; 233(2):254-61. PubMed ID: 18805435
[TBL] [Abstract][Full Text] [Related]
4. Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells.
West KA; Brognard J; Clark AS; Linnoila IR; Yang X; Swain SM; Harris C; Belinsky S; Dennis PA
J Clin Invest; 2003 Jan; 111(1):81-90. PubMed ID: 12511591
[TBL] [Abstract][Full Text] [Related]
5. Malignant transformation of human bronchial epithelial cells with the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
Zhou H; Calaf GM; Hei TK
Int J Cancer; 2003 Oct; 106(6):821-6. PubMed ID: 12918058
[TBL] [Abstract][Full Text] [Related]
6. Nongenomic beta estrogen receptors enhance beta1 adrenergic signaling induced by the nicotine-derived carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human small airway epithelial cells.
Majidi M; Al-Wadei HA; Takahashi T; Schuller HM
Cancer Res; 2007 Jul; 67(14):6863-71. PubMed ID: 17638897
[TBL] [Abstract][Full Text] [Related]
7. Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induces phosphorylation of mu- and m-calpain in association with increased secretion, cell migration, and invasion.
Xu L; Deng X
J Biol Chem; 2004 Dec; 279(51):53683-90. PubMed ID: 15471877
[TBL] [Abstract][Full Text] [Related]
8. Long-term exposure to extremely low-dose of nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induce non-malignant breast epithelial cell transformation through activation of the a9-nicotinic acetylcholine receptor-mediated signaling pathway.
Fararjeh AS; Tu SH; Chen LC; Cheng TC; Liu YR; Chang HL; Chang HW; Huang CC; Wang HR; Hwang-Verslues WW; Wu CH; Ho YS
Environ Toxicol; 2019 Jan; 34(1):73-82. PubMed ID: 30259641
[TBL] [Abstract][Full Text] [Related]
9. Ethanol and the tobacco-specific carcinogen, NNK, contribute to signaling in immortalized human pancreatic duct epithelial cells.
Askari MD; Tsao MS; Cekanova M; Schuller HM
Pancreas; 2006 Jul; 33(1):53-62. PubMed ID: 16804413
[TBL] [Abstract][Full Text] [Related]
10. 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone [corrected] induces CRM1-dependent p53 nuclear accumulation in human bronchial epithelial cells.
Chen L; Shao C; Cobos E; Wang JS; Gao W
Toxicol Sci; 2010 Jul; 116(1):206-15. PubMed ID: 20421341
[TBL] [Abstract][Full Text] [Related]
11. Nicotinic receptor-mediated activation by the tobacco-specific nitrosamine NNK of a Raf-1/MAP kinase pathway, resulting in phosphorylation of c-myc in human small cell lung carcinoma cells and pulmonary neuroendocrine cells.
Jull BA; Plummer HK; Schuller HM
J Cancer Res Clin Oncol; 2001 Dec; 127(12):707-17. PubMed ID: 11768610
[TBL] [Abstract][Full Text] [Related]
12. Green tea polyphenol EGCG suppresses cigarette smoke condensate-induced NF-kappaB activation in normal human bronchial epithelial cells.
Syed DN; Afaq F; Kweon MH; Hadi N; Bhatia N; Spiegelman VS; Mukhtar H
Oncogene; 2007 Feb; 26(5):673-82. PubMed ID: 16862172
[TBL] [Abstract][Full Text] [Related]
13. Development of ferret as a human lung cancer model by injecting 4-(Nmethyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
Aizawa K; Liu C; Veeramachaneni S; Hu KQ; Smith DE; Wang XD
Lung Cancer; 2013 Dec; 82(3):390-6. PubMed ID: 24396883
[TBL] [Abstract][Full Text] [Related]
14. Effects of tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) on the activation of ERK1/2 MAP kinases and the proliferation of human mammary epithelial cells.
Chen ZB; Liu C; Chen FQ; Li SY; Liang Q; Liu LY
Environ Toxicol Pharmacol; 2006 Nov; 22(3):283-91. PubMed ID: 21783722
[TBL] [Abstract][Full Text] [Related]
15. Metabolic study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone to the enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in vitro in human bronchial epithelial cells using chiral capillary electrophoresis.
Yang Y; Yu C; Zhou M; Pang N; Li N; Nie H; Liao J; Bai Y; Liu H
J Chromatogr A; 2011 Sep; 1218(37):6505-10. PubMed ID: 21791338
[TBL] [Abstract][Full Text] [Related]
16. Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone promotes functional cooperation of Bcl2 and c-Myc through phosphorylation in regulating cell survival and proliferation.
Jin Z; Gao F; Flagg T; Deng X
J Biol Chem; 2004 Sep; 279(38):40209-19. PubMed ID: 15210690
[TBL] [Abstract][Full Text] [Related]
17. NNK activates ERK1/2 and CREB/ATF-1 via beta-1-AR and EGFR signaling in human lung adenocarcinoma and small airway epithelial cells.
Laag E; Majidi M; Cekanova M; Masi T; Takahashi T; Schuller HM
Int J Cancer; 2006 Oct; 119(7):1547-52. PubMed ID: 16671086
[TBL] [Abstract][Full Text] [Related]
18. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone promotes esophageal squamous cell carcinoma growth via beta-adrenoceptors in vitro and in vivo.
Zhang N; Sun X; Sun M; Zhu S; Wang L; Ma D; Wang Y; Zhang S; Li P
PLoS One; 2015; 10(3):e0118845. PubMed ID: 25742648
[TBL] [Abstract][Full Text] [Related]
19. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) enhances invasiveness of lung cancer cells by up-regulating contactin-1 via the alpha7 nicotinic acetylcholine receptor/ERK signaling pathway.
Hung YH; Hung WC
Chem Biol Interact; 2009 May; 179(2-3):154-9. PubMed ID: 19027725
[TBL] [Abstract][Full Text] [Related]
20. Evidence for the epidermal growth factor receptor as a target for lung cancer prevention.
Lonardo F; Dragnev KH; Freemantle SJ; Ma Y; Memoli N; Sekula D; Knauth EA; Beebe JS; Dmitrovsky E
Clin Cancer Res; 2002 Jan; 8(1):54-60. PubMed ID: 11801540
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]