These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

196 related articles for article (PubMed ID: 15895232)

  • 1. Platinum-acridinylthiourea conjugates show cell line-specific cytotoxic enhancement in H460 lung carcinoma cells compared to cisplatin.
    Hess SM; Mounce AM; Sequeira RC; Augustus TM; Ackley MC; Bierbach U
    Cancer Chemother Pharmacol; 2005 Oct; 56(4):337-43. PubMed ID: 15895232
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gene-specific repair of Pt/DNA lesions and induction of apoptosis by the oral platinum drug JM216 in three human ovarian carcinoma cell lines sensitive and resistant to cisplatin.
    O'Neill CF; Koberle B; Masters JR; Kelland LR
    Br J Cancer; 1999 Dec; 81(8):1294-303. PubMed ID: 10604725
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis, biological activity, and DNA-damage profile of platinum-threading intercalator conjugates designed to target adenine.
    Guddneppanavar R; Saluta G; Kucera GL; Bierbach U
    J Med Chem; 2006 Jun; 49(11):3204-14. PubMed ID: 16722638
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-activity relationships in platinum-acridinylthiourea conjugates: effect of the thiourea nonleaving group on drug stability, nucleobase affinity, and in vitro cytotoxicity.
    Ackley MC; Barry CG; Mounce AM; Farmer MC; Springer BE; Day CS; Wright MW; Berners-Price SJ; Hess SM; Bierbach U
    J Biol Inorg Chem; 2004 Jun; 9(4):453-61. PubMed ID: 15067524
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Solution structural study of a DNA duplex containing the guanine-N7 adduct formed by a cytotoxic platinum-acridine hybrid agent.
    Baruah H; Wright MW; Bierbach U
    Biochemistry; 2005 Apr; 44(16):6059-70. PubMed ID: 15835895
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Unprecedented monofunctional metalation of adenine nucleobase in guanine- and thymine-containing dinucleotide sequences by a cytotoxic platinum-acridine hybrid agent.
    Barry CG; Baruah H; Bierbach U
    J Am Chem Soc; 2003 Aug; 125(32):9629-37. PubMed ID: 12904029
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of the diamine nonleaving group in platinum-acridinylthiourea conjugates on DNA damage and cytotoxicity.
    Guddneppanavar R; Choudhury JR; Kheradi AR; Steen BD; Saluta G; Kucera GL; Day CS; Bierbach U
    J Med Chem; 2007 May; 50(9):2259-63. PubMed ID: 17408248
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA minor groove adducts formed by a platinum-acridine conjugate inhibit association of tata-binding protein with its cognate sequence.
    Budiman ME; Bierbach U; Alexander RW
    Biochemistry; 2005 Aug; 44(33):11262-8. PubMed ID: 16101310
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Duplex-promoted platination of adenine-N3 in the minor groove of DNA: challenging a longstanding bioinorganic paradigm.
    Barry CG; Day CS; Bierbach U
    J Am Chem Soc; 2005 Feb; 127(4):1160-9. PubMed ID: 15669855
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Influence of a novel platinum compound--cis-dichloro (dimethylsulphoxide) (1-beta-D-rybofuranosyl-1,2,4-triazolo-3-arboxyamide) platinum (II)--"Pt-rib-1"--on cell cycle and apoptosis in ClS91 and B16 mouse melanoma in vitro.
    Drewa T; Olszewska-Słonina D; Woźniak A; Styczyński J; Drewa G; Szłyk E; Lakomska I; Kobe J; Czajkowski R
    Acta Pol Pharm; 2004; 61(1):39-44. PubMed ID: 15259856
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Palladium(II) and platinum(II) organometallic complexes with 4,7-dihydro-5-methyl-7-oxo[1,2,4]triazolo[1,5-a]pyrimidine. Antitumor activity of the platinum compounds.
    Ruiz J; Villa MD; Cutillas N; López G; de Haro C; Bautista D; Moreno V; Valencia L
    Inorg Chem; 2008 Jun; 47(11):4490-505. PubMed ID: 18447329
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A non-crosslinking platinum-acridine hybrid agent shows enhanced cytotoxicity compared to clinical BCNU and cisplatin in glioblastoma cells.
    Hess SM; Anderson JG; Bierbach U
    Bioorg Med Chem Lett; 2005 Jan; 15(2):443-6. PubMed ID: 15603970
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enhanced replicative bypass of platinum-DNA adducts in cisplatin-resistant human ovarian carcinoma cell lines.
    Mamenta EL; Poma EE; Kaufmann WK; Delmastro DA; Grady HL; Chaney SG
    Cancer Res; 1994 Jul; 54(13):3500-5. PubMed ID: 8012973
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antitumor activity of a new platinum(II) complex with low nephrotoxicity and genotoxicity.
    Marzano C; Bettio F; Baccichetti F; Trevisan A; Giovagnini L; Fregona D
    Chem Biol Interact; 2004 Jun; 148(1-2):37-48. PubMed ID: 15223355
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Accumulation, platinum-DNA adduct formation and cytotoxicity of cisplatin, oxaliplatin and satraplatin in sensitive and resistant human osteosarcoma cell lines, characterized by p53 wild-type status.
    Martelli L; Di Mario F; Botti P; Ragazzi E; Martelli M; Kelland L
    Biochem Pharmacol; 2007 Jun; 74(1):20-7. PubMed ID: 17466278
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Unique base-step recognition by a platinum-acridinylthiourea conjugate leads to a DNA damage profile complementary to that of the anticancer drug cisplatin.
    Budiman ME; Alexander RW; Bierbach U
    Biochemistry; 2004 Jul; 43(26):8560-7. PubMed ID: 15222767
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Platinum(IV) complex with adamantylamine overcomes intrinsic resistance to cisplatin in ovarian cancer cells.
    Horváth V; Blanárová O; Svihálková-Sindlerová L; Soucek K; Hofmanová J; Sova P; Kroutil A; Fedorocko P; Kozubík A
    Gynecol Oncol; 2006 Jul; 102(1):32-40. PubMed ID: 16364413
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and activity of a trinuclear platinum complex: [{trans-PtCl(NH3)2}2mu-{trans-Pt(3-hydroxypyridine)2(H2N(CH2)6NH2)2}]Cl4 in ovarian cancer cell lines.
    Tayyem H; Huq F; Yu JQ; Beale P; Fisher K
    ChemMedChem; 2008 Jan; 3(1):145-51. PubMed ID: 17963210
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ATP sensitizes H460 lung carcinoma cells to cisplatin-induced apoptosis.
    Swennen EL; Ummels V; Buss I; Jaehde U; Bast A; Dagnelie PC
    Chem Biol Interact; 2010 Mar; 184(3):338-45. PubMed ID: 20156429
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel synthetic compound induces lung carcinoma cell death associated with inhibiting ERK and CDC2 phosphorylation via a p53-independent pathway.
    Hsu TS; Chen C; Lee PT; Chiu SJ; Liu HF; Tsai CC; Chao JI
    Cancer Chemother Pharmacol; 2008 Oct; 62(5):799-808. PubMed ID: 18193228
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.