BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

595 related articles for article (PubMed ID: 15899838)

  • 1. Milk thistle and prostate cancer: differential effects of pure flavonolignans from Silybum marianum on antiproliferative end points in human prostate carcinoma cells.
    Davis-Searles PR; Nakanishi Y; Kim NC; Graf TN; Oberlies NH; Wani MC; Wall ME; Agarwal R; Kroll DJ
    Cancer Res; 2005 May; 65(10):4448-57. PubMed ID: 15899838
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gram-scale purification of flavonolignan diastereoisomers from Silybum marianum (Milk Thistle) extract in support of preclinical in vivo studies for prostate cancer chemoprevention.
    Graf TN; Wani MC; Agarwal R; Kroll DJ; Oberlies NH
    Planta Med; 2007 Nov; 73(14):1495-501. PubMed ID: 17948171
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Isosilybin B and isosilybin A inhibit growth, induce G1 arrest and cause apoptosis in human prostate cancer LNCaP and 22Rv1 cells.
    Deep G; Oberlies NH; Kroll DJ; Agarwal R
    Carcinogenesis; 2007 Jul; 28(7):1533-42. PubMed ID: 17389612
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The effect of milk thistle (Silybum marianum) and its main flavonolignans on CYP2C8 enzyme activity in human liver microsomes.
    Albassam AA; Frye RF; Markowitz JS
    Chem Biol Interact; 2017 Jun; 271():24-29. PubMed ID: 28457856
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Silibinin down-regulates prostate epithelium-derived Ets transcription factor in LNCaP prostate cancer cells.
    Thelen P; Jarry H; Ringert RH; Wuttke W
    Planta Med; 2004 May; 70(5):397-400. PubMed ID: 15124082
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of telomerase activity and secretion of prostate specific antigen by silibinin in prostate cancer cells.
    Thelen P; Wuttke W; Jarry H; Grzmil M; Ringert RH
    J Urol; 2004 May; 171(5):1934-8. PubMed ID: 15076315
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Antiproliferative and apoptotic effects of silibinin in rat prostate cancer cells.
    Tyagi A; Bhatia N; Condon MS; Bosland MC; Agarwal C; Agarwal R
    Prostate; 2002 Nov; 53(3):211-7. PubMed ID: 12386921
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enhanced production of silymarin by Ag+ elicitor in cell suspension cultures of Silybum marianum.
    Ashtiani SR; Hasanloo T; Bihamta MR
    Pharm Biol; 2010 Jun; 48(6):708-15. PubMed ID: 20645746
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identifying the differential effects of silymarin constituents on cell growth and cell cycle regulatory molecules in human prostate cancer cells.
    Deep G; Oberlies NH; Kroll DJ; Agarwal R
    Int J Cancer; 2008 Jul; 123(1):41-50. PubMed ID: 18435416
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Gene profiling and promoter reporter assays: novel tools for comparing the biological effects of botanical extracts on human prostate cancer cells and understanding their mechanisms of action.
    Bigler D; Gulding KM; Dann R; Sheabar FZ; Conaway MR; Theodorescu D
    Oncogene; 2003 Feb; 22(8):1261-72. PubMed ID: 12606954
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Flavonolignans from Aspergillus iizukae, a fungal endophyte of milk thistle (Silybum marianum).
    El-Elimat T; Raja HA; Graf TN; Faeth SH; Cech NB; Oberlies NH
    J Nat Prod; 2014 Feb; 77(2):193-9. PubMed ID: 24456525
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Large-scale isolation of flavonolignans from Silybum marianum extract affords new minor constituents and preliminary structure-activity relationships.
    Sy-Cordero A; Graf TN; Nakanishi Y; Wani MC; Agarwal R; Kroll DJ; Oberlies NH
    Planta Med; 2010 Apr; 76(6):644-7. PubMed ID: 19941262
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Silymarin and silibinin cause G1 and G2-M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone silibinin with flavanolignan mixture silymarin.
    Deep G; Singh RP; Agarwal C; Kroll DJ; Agarwal R
    Oncogene; 2006 Feb; 25(7):1053-69. PubMed ID: 16205633
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dietary feeding of silibinin inhibits advance human prostate carcinoma growth in athymic nude mice and increases plasma insulin-like growth factor-binding protein-3 levels.
    Singh RP; Dhanalakshmi S; Tyagi AK; Chan DC; Agarwal C; Agarwal R
    Cancer Res; 2002 Jun; 62(11):3063-9. PubMed ID: 12036915
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular structure and stereochemistry of silybin A, silybin B, isosilybin A, and isosilybin B, Isolated from Silybum marianum (milk thistle).
    Lee DY; Liu Y
    J Nat Prod; 2003 Sep; 66(9):1171-4. PubMed ID: 14510591
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A silychristin isomer and variation of flavonolignan levels in milk thistle (Silybum marianum) fruits.
    Smith WA; Lauren DR; Burgess EJ; Perry NB; Martin RJ
    Planta Med; 2005 Sep; 71(9):877-80. PubMed ID: 16206045
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The study of flavonolignan association patterns in fruits of diverging Silybum marianum (L.) Gaertn. chemotypes provides new insights into the silymarin biosynthetic pathway.
    Martinelli T; Whittaker A; Benedettelli S; Carboni A; Andrzejewska J
    Phytochemistry; 2017 Dec; 144():9-18. PubMed ID: 28863306
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chemotaxonomic and biosynthetic relationships between flavonolignans produced by Silybum marianum populations.
    AbouZid SF; Ahmed HS; Moawad AS; Owis AI; Chen SN; Nachtergael A; McAlpine JB; Brent Friesen J; Pauli GF
    Fitoterapia; 2017 Jun; 119():175-184. PubMed ID: 28392269
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Angiopreventive efficacy of pure flavonolignans from milk thistle extract against prostate cancer: targeting VEGF-VEGFR signaling.
    Deep G; Gangar SC; Rajamanickam S; Raina K; Gu M; Agarwal C; Oberlies NH; Agarwal R
    PLoS One; 2012; 7(4):e34630. PubMed ID: 22514647
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Two flavonolignans from milk thistle (Silybum marianum) inhibit CYP2C9-mediated warfarin metabolism at clinically achievable concentrations.
    Brantley SJ; Oberlies NH; Kroll DJ; Paine MF
    J Pharmacol Exp Ther; 2010 Mar; 332(3):1081-7. PubMed ID: 19934397
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.