BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

280 related articles for article (PubMed ID: 15901797)

  • 41. Amino acid prodrugs of acyclovir as possible antiviral agents against ocular HSV-1 infections: interactions with the neutral and cationic amino acid transporter on the corneal epithelium.
    Anand BS; Katragadda S; Nashed YE; Mitra AK
    Curr Eye Res; 2004; 29(2-3):153-66. PubMed ID: 15512962
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Synthesis, transport and pharmacokinetics of 5'-amino acid ester prodrugs of 1-beta-D-arabinofuranosylcytosine.
    Sun Y; Sun J; Shi S; Jing Y; Yin S; Chen Y; Li G; Xu Y; He Z
    Mol Pharm; 2009; 6(1):315-25. PubMed ID: 19115956
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Antibody-directed enzyme prodrug therapy with the T268G mutant of human carboxypeptidase A1: in vitro and in vivo studies with prodrugs of methotrexate and the thymidylate synthase inhibitors GW1031 and GW1843.
    Wolfe LA; Mullin RJ; Laethem R; Blumenkopf TA; Cory M; Miller JF; Keith BR; Humphreys J; Smith GK
    Bioconjug Chem; 1999; 10(1):38-48. PubMed ID: 9893962
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Nucleoside ester prodrug substrate specificity of liver carboxylesterase.
    Landowski CP; Lorenzi PL; Song X; Amidon GL
    J Pharmacol Exp Ther; 2006 Feb; 316(2):572-80. PubMed ID: 16223870
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Dipeptide derivatives of AZT: synthesis, chemical stability, activation in human plasma, hPEPT1 affinity, and antiviral activity.
    Santos C; Morais J; Gouveia L; de Clercq E; Pannecouque C; Nielsen CU; Steffansen B; Moreira R; Gomes P
    ChemMedChem; 2008 Jun; 3(6):970-8. PubMed ID: 18389514
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Susceptibilities of human cytomegalovirus clinical isolates and other herpesviruses to new acetylated, tetrahalogenated benzimidazole D-ribonucleosides.
    Hwang JS; Schilf R; Drach JC; Townsend LB; Bogner E
    Antimicrob Agents Chemother; 2009 Dec; 53(12):5095-101. PubMed ID: 19786605
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Improved Protease-Targeting and Biopharmaceutical Properties of Novel Prodrugs of Ganciclovir.
    Sun K; Xu H; Hilfinger JL; Lee KD; Provoda CJ; Sabit H; Amidon GL
    Mol Pharm; 2018 Feb; 15(2):410-419. PubMed ID: 29251944
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Increased bioavailability of tricin-amino acid derivatives via a prodrug approach.
    Ninomiya M; Tanaka K; Tsuchida Y; Muto Y; Koketsu M; Watanabe K
    J Med Chem; 2011 Mar; 54(5):1529-36. PubMed ID: 21319803
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Novel prodrugs of tegafur that display improved anticancer activity and antiangiogenic properties.
    Engel D; Nudelman A; Tarasenko N; Levovich I; Makarovsky I; Sochotnikov S; Tarasenko I; Rephaeli A
    J Med Chem; 2008 Jan; 51(2):314-23. PubMed ID: 18163551
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Development of water-soluble prodrugs of the HIV-1 protease inhibitor KNI-727: importance of the conversion time for higher gastrointestinal absorption of prodrugs based on spontaneous chemical cleavage.
    Sohma Y; Hayashi Y; Ito T; Matsumoto H; Kimura T; Kiso Y
    J Med Chem; 2003 Sep; 46(19):4124-35. PubMed ID: 12954064
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Preclinical pharmacokinetics and in vitro metabolism of brivanib (BMS-540215), a potent VEGFR2 inhibitor and its alanine ester prodrug brivanib alaninate.
    Marathe PH; Kamath AV; Zhang Y; D'Arienzo C; Bhide R; Fargnoli J
    Cancer Chemother Pharmacol; 2009 Dec; 65(1):55-66. PubMed ID: 19396600
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Increasing oral absorption of polar neuraminidase inhibitors: a prodrug transporter approach applied to oseltamivir analogue.
    Gupta D; Varghese Gupta S; Dahan A; Tsume Y; Hilfinger J; Lee KD; Amidon GL
    Mol Pharm; 2013 Feb; 10(2):512-22. PubMed ID: 23244438
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Design, synthesis and antiviral activity of novel 4,5-disubstituted 7-(beta-D-ribofuranosyl)pyrrolo[2,3-d][1,2,3]triazines and the novel 3-amino-5-methyl-1-(beta-D-ribofuranosyl)- and 3-amino-5-methyl-1-(2-deoxy-beta-D-ribofuranosyl)-1,5-dihydro-1,4,5,6,7,8-hexaazaacenaphthylene as analogues of triciribine.
    Migawa MT; Drach JC; Townsend LB
    J Med Chem; 2005 Jun; 48(11):3840-51. PubMed ID: 15916436
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Synthesis of fluorosugar analogues of 2,5,6-trichloro-1-(beta-D-ribofuranosyl)benzimidazole as antivirals with potentially increased glycosidic bond stability.
    Gudmundsson KS; Freeman GA; Drach JC; Townsend LB
    J Med Chem; 2000 Jun; 43(12):2473-8. PubMed ID: 10882375
    [TBL] [Abstract][Full Text] [Related]  

  • 55. In vitro evaluation of dendrimer prodrugs for oral drug delivery.
    Najlah M; Freeman S; Attwood D; D'Emanuele A
    Int J Pharm; 2007 May; 336(1):183-90. PubMed ID: 17188439
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Enhanced cellular uptake of Ara-C via a peptidomimetic prodrug, L-valyl-ara-C in Caco-2 cells.
    Cheon EP; Hong JH; Han HK
    J Pharm Pharmacol; 2006 Jul; 58(7):927-32. PubMed ID: 16805952
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Activities of benzimidazole D- and L-ribonucleosides in animal models of cytomegalovirus infections.
    Kern ER; Hartline CB; Rybak RJ; Drach JC; Townsend LB; Biron KK; Bidanset DJ
    Antimicrob Agents Chemother; 2004 May; 48(5):1749-55. PubMed ID: 15105130
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Stereospecific chemical and enzymatic stability of phosphoramidate triester prodrugs of d4T in vitro.
    Siccardi D; Gumbleton M; Omidi Y; McGuigan C
    Eur J Pharm Sci; 2004 May; 22(1):25-31. PubMed ID: 15113580
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Metabolism and pharmacokinetics of a double prodrug of ganciclovir in the rat and monkey.
    Krasny HC; Beauchamp L; Krenitsky TA; de Miranda P
    Drug Metab Dispos; 1995 Nov; 23(11):1242-7. PubMed ID: 8591725
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Floxuridine amino acid ester prodrugs: enhancing Caco-2 permeability and resistance to glycosidic bond metabolism.
    Landowski CP; Song X; Lorenzi PL; Hilfinger JM; Amidon GL
    Pharm Res; 2005 Sep; 22(9):1510-8. PubMed ID: 16132363
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 14.