BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 15908798)

  • 1. The Mre11/Rad50/Nbs1 complex and its role as a DNA double-strand break sensor for ATM.
    Paull TT; Lee JH
    Cell Cycle; 2005 Jun; 4(6):737-40. PubMed ID: 15908798
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Resection of DNA double-strand breaks activates Mre11-Rad50-Nbs1- and Rad9-Hus1-Rad1-dependent mechanisms that redundantly promote ATR checkpoint activation and end processing in Xenopus egg extracts.
    Tatsukawa K; Sakamoto R; Kawasoe Y; Kubota Y; Tsurimoto T; Takahashi TS; Ohashi E
    Nucleic Acids Res; 2024 Apr; 52(6):3146-3163. PubMed ID: 38349040
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enhanced phosphorylation of Nbs1, a member of DNA repair/checkpoint complex Mre11-RAD50-Nbs1, can be targeted to increase the efficacy of imatinib mesylate against BCR/ABL-positive leukemia cells.
    Rink L; Slupianek A; Stoklosa T; Nieborowska-Skorska M; Urbanska K; Seferynska I; Reiss K; Skorski T
    Blood; 2007 Jul; 110(2):651-60. PubMed ID: 17431132
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MRE11-RAD50-NBS1 Complex Is Sufficient to Promote Transcription by RNA Polymerase II at Double-Strand Breaks by Melting DNA Ends.
    Sharma S; Anand R; Zhang X; Francia S; Michelini F; Galbiati A; Williams H; Ronato DA; Masson JY; Rothenberg E; Cejka P; d'Adda di Fagagna F
    Cell Rep; 2021 Jan; 34(1):108565. PubMed ID: 33406426
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Research Progress in the Roles of MRE11-RAD50-NBS1 Complex and Human Diseases].
    Xu XH; Liu YD
    Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2024 Apr; 46(2):232-241. PubMed ID: 38686720
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Mre11 complex is required for ATM activation and the G2/M checkpoint.
    Carson CT; Schwartz RA; Stracker TH; Lilley CE; Lee DV; Weitzman MD
    EMBO J; 2003 Dec; 22(24):6610-20. PubMed ID: 14657032
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair.
    Zhang J; Willers H; Feng Z; Ghosh JC; Kim S; Weaver DT; Chung JH; Powell SN; Xia F
    Mol Cell Biol; 2004 Jan; 24(2):708-18. PubMed ID: 14701743
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ATM directs DNA damage responses and proteostasis via genetically separable pathways.
    Lee JH; Mand MR; Kao CH; Zhou Y; Ryu SW; Richards AL; Coon JJ; Paull TT
    Sci Signal; 2018 Jan; 11(512):. PubMed ID: 29317520
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors.
    Hartlerode AJ; Morgan MJ; Wu Y; Buis J; Ferguson DO
    Nat Struct Mol Biol; 2015 Sep; 22(9):736-43. PubMed ID: 26280532
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Rad50 hook domain regulates DNA damage signaling and tumorigenesis.
    Roset R; Inagaki A; Hohl M; Brenet F; Lafrance-Vanasse J; Lange J; Scandura JM; Tainer JA; Keeney S; Petrini JH
    Genes Dev; 2014 Mar; 28(5):451-62. PubMed ID: 24532689
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Modeling cancer genomic data in yeast reveals selection against ATM function during tumorigenesis.
    Hohl M; Mojumdar A; Hailemariam S; Kuryavyi V; Ghisays F; Sorenson K; Chang M; Taylor BS; Patel DJ; Burgers PM; Cobb JA; Petrini JHJ
    PLoS Genet; 2020 Mar; 16(3):e1008422. PubMed ID: 32187176
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chk2 suppresses the oncogenic potential of DNA replication-associated DNA damage.
    Stracker TH; Couto SS; Cordon-Cardo C; Matos T; Petrini JH
    Mol Cell; 2008 Jul; 31(1):21-32. PubMed ID: 18614044
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Homeodomain Proteins Directly Regulate ATM Kinase Activity.
    Johnson TE; Lee JH; Myler LR; Zhou Y; Mosley TJ; Yang SH; ; Uprety N; Kim J; Paull TT
    Cell Rep; 2018 Aug; 24(6):1471-1483. PubMed ID: 30089259
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.
    Syed A; Tainer JA
    Annu Rev Biochem; 2018 Jun; 87():263-294. PubMed ID: 29709199
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway.
    Kitagawa R; Bakkenist CJ; McKinnon PJ; Kastan MB
    Genes Dev; 2004 Jun; 18(12):1423-38. PubMed ID: 15175241
    [TBL] [Abstract][Full Text] [Related]  

  • 16. RBBP4 regulates the expression of the Mre11-Rad50-NBS1 (MRN) complex and promotes DNA double-strand break repair to mediate glioblastoma chemoradiotherapy resistance.
    Li J; Song C; Gu J; Li C; Zang W; Shi L; Chen L; Zhu L; Zhou M; Wang T; Li H; Qi S; Lu Y
    Cancer Lett; 2023 Mar; 557():216078. PubMed ID: 36736531
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bone Marrow Failure and Immunodeficiency Associated with Human RAD50 Variants.
    Takagi M; Hoshino A; Bousset K; Röddecke J; Martin HL; Folcut I; Tomomasa D; Yang X; Kobayashi J; Sakata N; Yoshida K; Miyano S; Ogawa S; Kojima S; Morio T; Dörk T; Kanegane H
    J Clin Immunol; 2023 Nov; 43(8):2136-2145. PubMed ID: 37794136
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Disordered regions mediate the interaction of p53 and MRE11.
    Usluer S; Galhuber M; Khanna Y; Bourgeois B; Spreitzer E; Michenthaler H; Prokesch A; Madl T
    Biochim Biophys Acta Mol Cell Res; 2024 Feb; 1871(2):119654. PubMed ID: 38123020
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Mre11 complex mediates the S-phase checkpoint through an interaction with replication protein A.
    Olson E; Nievera CJ; Liu E; Lee AY; Chen L; Wu X
    Mol Cell Biol; 2007 Sep; 27(17):6053-67. PubMed ID: 17591703
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes.
    Greenberg RA; Sobhian B; Pathania S; Cantor SB; Nakatani Y; Livingston DM
    Genes Dev; 2006 Jan; 20(1):34-46. PubMed ID: 16391231
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.