449 related articles for article (PubMed ID: 15917100)
1. Age-dependent differential expression of BACE splice variants in brain regions of tg2576 mice.
Zohar O; Pick CG; Cavallaro S; Chapman J; Katzav A; Milman A; Alkon DL
Neurobiol Aging; 2005; 26(8):1167-75. PubMed ID: 15917100
[TBL] [Abstract][Full Text] [Related]
2. A novel beta-site amyloid precursor protein cleaving enzyme (BACE) isoform regulated by nonsense-mediated mRNA decay and proteasome-dependent degradation.
Tanahashi H; Tabira T
Neurosci Lett; 2007 Nov; 428(2-3):103-8. PubMed ID: 17961921
[TBL] [Abstract][Full Text] [Related]
3. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
Evin G; Zhu A; Holsinger RM; Masters CL; Li QX
J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315
[TBL] [Abstract][Full Text] [Related]
4. Astrocytic expression of the Alzheimer's disease beta-secretase (BACE1) is stimulus-dependent.
Hartlage-Rübsamen M; Zeitschel U; Apelt J; Gärtner U; Franke H; Stahl T; Günther A; Schliebs R; Penkowa M; Bigl V; Rossner S
Glia; 2003 Jan; 41(2):169-79. PubMed ID: 12509807
[TBL] [Abstract][Full Text] [Related]
5. Targeting BACE with small inhibitory nucleic acids - a future for Alzheimer's disease therapy?
Nawrot B
Acta Biochim Pol; 2004; 51(2):431-44. PubMed ID: 15218540
[TBL] [Abstract][Full Text] [Related]
6. Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo.
Hussain I; Hawkins J; Harrison D; Hille C; Wayne G; Cutler L; Buck T; Walter D; Demont E; Howes C; Naylor A; Jeffrey P; Gonzalez MI; Dingwall C; Michel A; Redshaw S; Davis JB
J Neurochem; 2007 Feb; 100(3):802-9. PubMed ID: 17156133
[TBL] [Abstract][Full Text] [Related]
7. Neuronal and glial beta-secretase (BACE) protein expression in transgenic Tg2576 mice with amyloid plaque pathology.
Rossner S; Apelt J; Schliebs R; Perez-Polo JR; Bigl V
J Neurosci Res; 2001 Jun; 64(5):437-46. PubMed ID: 11391698
[TBL] [Abstract][Full Text] [Related]
8. Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients.
Li R; Lindholm K; Yang LB; Yue X; Citron M; Yan R; Beach T; Sue L; Sabbagh M; Cai H; Wong P; Price D; Shen Y
Proc Natl Acad Sci U S A; 2004 Mar; 101(10):3632-7. PubMed ID: 14978286
[TBL] [Abstract][Full Text] [Related]
9. Beta-amyloid secretases and beta-amloid degrading enzyme expression in lens.
Li G; Percontino L; Sun Q; Qazi AS; Frederikse PH
Mol Vis; 2003 May; 9():179-83. PubMed ID: 12740567
[TBL] [Abstract][Full Text] [Related]
10. Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1.
Ohno M; Chang L; Tseng W; Oakley H; Citron M; Klein WL; Vassar R; Disterhoft JF
Eur J Neurosci; 2006 Jan; 23(1):251-60. PubMed ID: 16420434
[TBL] [Abstract][Full Text] [Related]
11. Metallothionein-I and -III expression in animal models of Alzheimer disease.
Carrasco J; Adlard P; Cotman C; Quintana A; Penkowa M; Xu F; Van Nostrand WE; Hidalgo J
Neuroscience; 2006 Dec; 143(4):911-22. PubMed ID: 17027170
[TBL] [Abstract][Full Text] [Related]
12. Expression and activity of beta-site amyloid precursor protein cleaving enzyme in Alzheimer's disease.
Johnston JA; Liu WW; Todd SA; Coulson DT; Murphy S; Irvine GB; Passmore AP
Biochem Soc Trans; 2005 Nov; 33(Pt 5):1096-100. PubMed ID: 16246054
[TBL] [Abstract][Full Text] [Related]
13. BACE (beta-secretase) modulates the processing of APLP2 in vivo.
Pastorino L; Ikin AF; Lamprianou S; Vacaresse N; Revelli JP; Platt K; Paganetti P; Mathews PM; Harroch S; Buxbaum JD
Mol Cell Neurosci; 2004 Apr; 25(4):642-9. PubMed ID: 15080893
[TBL] [Abstract][Full Text] [Related]
14. Immunotherapy against APP beta-secretase cleavage site improves cognitive function and reduces neuroinflammation in Tg2576 mice without a significant effect on brain abeta levels.
Rakover I; Arbel M; Solomon B
Neurodegener Dis; 2007; 4(5):392-402. PubMed ID: 17536186
[TBL] [Abstract][Full Text] [Related]
15. 1-(3',4'-Dichloro-2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid (CHF5074), a novel gamma-secretase modulator, reduces brain beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease without causing peripheral toxicity.
Imbimbo BP; Del Giudice E; Colavito D; D'Arrigo A; Dalle Carbonare M; Villetti G; Facchinetti F; Volta R; Pietrini V; Baroc MF; Serneels L; De Strooper B; Leon A
J Pharmacol Exp Ther; 2007 Dec; 323(3):822-30. PubMed ID: 17895400
[TBL] [Abstract][Full Text] [Related]
16. Promising multifunctional anti-Alzheimer's dimer bis(7)-Cognitin acting as an activator of protein kinase C regulates activities of alpha-secretase and BACE-1 concurrently.
Fu H; Dou J; Li W; Cui W; Mak S; Hu Q; Luo J; Lam CS; Pang Y; Youdim MB; Han Y
Eur J Pharmacol; 2009 Nov; 623(1-3):14-21. PubMed ID: 19765582
[TBL] [Abstract][Full Text] [Related]
17. Quantification and distribution of beta-secretase alternative splice variants in the rat and human brain.
Zohar O; Cavallaro S; D'Agata V; Alkon DL
Brain Res Mol Brain Res; 2003 Jul; 115(1):63-8. PubMed ID: 12824056
[TBL] [Abstract][Full Text] [Related]
18. Dynamics of {beta}-amyloid reductions in brain, cerebrospinal fluid, and plasma of {beta}-amyloid precursor protein transgenic mice treated with a {gamma}-secretase inhibitor.
Barten DM; Guss VL; Corsa JA; Loo A; Hansel SB; Zheng M; Munoz B; Srinivasan K; Wang B; Robertson BJ; Polson CT; Wang J; Roberts SB; Hendrick JP; Anderson JJ; Loy JK; Denton R; Verdoorn TA; Smith DW; Felsenstein KM
J Pharmacol Exp Ther; 2005 Feb; 312(2):635-43. PubMed ID: 15452193
[TBL] [Abstract][Full Text] [Related]
19. Modeling of substrate specificity of the Alzheimer's disease amyloid precursor protein beta-secretase.
Sauder JM; Arthur JW; Dunbrack RL
J Mol Biol; 2000 Jul; 300(2):241-8. PubMed ID: 10873463
[TBL] [Abstract][Full Text] [Related]
20. In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1.
Sankaranarayanan S; Price EA; Wu G; Crouthamel MC; Shi XP; Tugusheva K; Tyler KX; Kahana J; Ellis J; Jin L; Steele T; Stachel S; Coburn C; Simon AJ
J Pharmacol Exp Ther; 2008 Mar; 324(3):957-69. PubMed ID: 18156464
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
