These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 15921914)

  • 1. Exploration of orally available calpain inhibitors: peptidyl alpha-ketoamides containing an amphiphile at P3 site.
    Shirasaki Y; Miyashita H; Yamaguchi M; Inoue J; Nakamura M
    Bioorg Med Chem; 2005 Jul; 13(14):4473-84. PubMed ID: 15921914
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Exploration of orally available calpain inhibitors. Part 3: Dipeptidyl alpha-ketoamide derivatives containing pyridine moiety.
    Shirasaki Y; Miyashita H; Yamaguchi M
    Bioorg Med Chem; 2006 Aug; 14(16):5691-8. PubMed ID: 16651001
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Benzoylalanine-derived ketoamides carrying vinylbenzyl amino residues: discovery of potent water-soluble calpain inhibitors with oral bioavailability.
    Lubisch W; Beckenbach E; Bopp S; Hofmann HP; Kartal A; Kästel C; Lindner T; Metz-Garrecht M; Reeb J; Regner F; Vierling M; Möller A
    J Med Chem; 2003 Jun; 46(12):2404-12. PubMed ID: 12773044
    [TBL] [Abstract][Full Text] [Related]  

  • 4. P2-P3 conformationally constrained ketoamide-based inhibitors of cathepsin K.
    Barrett DG; Boncek VM; Catalano JG; Deaton DN; Hassell AM; Jurgensen CH; Long ST; McFadyen RB; Miller AB; Miller LR; Payne JA; Ray JA; Samano V; Shewchuk LM; Tavares FX; Wells-Knecht KJ; Willard DH; Wright LL; Zhou HQ
    Bioorg Med Chem Lett; 2005 Aug; 15(15):3540-6. PubMed ID: 15982880
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Potent and selective P2-P3 ketoamide inhibitors of cathepsin K with good pharmacokinetic properties via favorable P1', P1, and/or P3 substitutions.
    Barrett DG; Catalano JG; Deaton DN; Hassell AM; Long ST; Miller AB; Miller LR; Shewchuk LM; Wells-Knecht KJ; Willard DH; Wright LL
    Bioorg Med Chem Lett; 2004 Oct; 14(19):4897-902. PubMed ID: 15341947
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel, potent P2-P3 pyrrolidine derivatives of ketoamide-based cathepsin K inhibitors.
    Barrett DG; Catalano JG; Deaton DN; Hassell AM; Long ST; Miller AB; Miller LR; Ray JA; Samano V; Shewchuk LM; Wells-Knecht KJ; Willard DH; Wright LL
    Bioorg Med Chem Lett; 2006 Mar; 16(6):1735-9. PubMed ID: 16376075
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Exploration of orally available calpain inhibitors 2: peptidyl hemiacetal derivatives.
    Shirasaki Y; Nakamura M; Yamaguchi M; Miyashita H; Sakai O; Inoue J
    J Med Chem; 2006 Jun; 49(13):3926-32. PubMed ID: 16789748
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 8. Pharmacological optimization of orally bioavailable 2-pyridone-containing peptidomimetics.
    Dragovich PS; Prins TJ; Zhou R; Johnson TO; Hua Y; Luu HT; Sakata SK; Brown EL; Maldonado FC; Tuntland T; Lee CA; Fuhrman SA; Zalman LS; Patick AK; Matthews DA; Wu EY; Guo M; Borer BC; Nayyar NK; Moran T; Chen L; Rejto PA; Rose PW; Guzman MC; Dovalsantos EZ; Lee S; McGee K; Mohajeri M; Liese A; Tao J; Kosa MB; Liu B; Batugo MR; Gleeson JP; Wu ZP; Liu J; Meador JW; Ferre RA
    J Med Chem; 2003 Oct; 46(21):4572-85. PubMed ID: 14521419
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel peptidyl alpha-keto amide inhibitors of calpains and other cysteine proteases.
    Li Z; Ortega-Vilain AC; Patil GS; Chu DL; Foreman JE; Eveleth DD; Powers JC
    J Med Chem; 1996 Sep; 39(20):4089-98. PubMed ID: 8831774
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Orally bioavailable small molecule ketoamide-based inhibitors of cathepsin K.
    Barrett DG; Catalano JG; Deaton DN; Long ST; Miller LR; Tavares FX; Wells-Knecht KJ; Wright LL; Zhou HQ
    Bioorg Med Chem Lett; 2004 May; 14(10):2543-6. PubMed ID: 15109647
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of phenyl alanine derived ketoamides carrying benzoyl residues as novel calpain inhibitors.
    Lubisch W; Möller A
    Bioorg Med Chem Lett; 2002 May; 12(10):1335-8. PubMed ID: 11992771
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A novel series of urea-based peptidomimetic calpain inhibitors.
    Sanders ML; Donkor IO
    Bioorg Med Chem Lett; 2006 Apr; 16(7):1965-8. PubMed ID: 16412635
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design and synthesis of 4-aryl-4-oxobutanoic acid amides as calpain inhibitors.
    Zhang Y; Jung SY; Jin C; Kim ND; Gong P; Lee YS
    Bioorg Med Chem Lett; 2009 Jan; 19(2):502-7. PubMed ID: 19041242
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Peptide alpha-keto ester, alpha-keto amide, and alpha-keto acid inhibitors of calpains and other cysteine proteases.
    Li Z; Patil GS; Golubski ZE; Hori H; Tehrani K; Foreman JE; Eveleth DD; Bartus RT; Powers JC
    J Med Chem; 1993 Oct; 36(22):3472-80. PubMed ID: 8230139
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological evaluation of chromone carboxamides as calpain inhibitors.
    Lee KS; Seo SH; Lee YH; Kim HD; Son MH; Chung BY; Lee JY; Jin C; Lee YS
    Bioorg Med Chem Lett; 2005 Jun; 15(11):2857-60. PubMed ID: 15911268
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Succinic acid amides as P2-P3 replacements for inhibitors of interleukin-1beta converting enzyme (ICE or caspase 1).
    Galatsis P; Caprathe B; Gilmore J; Thomas A; Linn K; Sheehan S; Harter W; Kostlan C; Lunney E; Stankovic C; Rubin J; Brady K; Allen H; Talanian R
    Bioorg Med Chem Lett; 2010 Sep; 20(17):5184-90. PubMed ID: 20656488
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Exploration of peptidyl hydrazones as water-soluble calpain inhibitors.
    Nakamura M; Inoue J
    Bioorg Med Chem Lett; 2002 Jun; 12(12):1603-6. PubMed ID: 12039572
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Developments in the design and synthesis of calpain inhibitors.
    Neffe AT; Abell AD
    Curr Opin Drug Discov Devel; 2005 Nov; 8(6):684-700. PubMed ID: 16312145
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Acyclic, orally bioavailable ketone-based cathepsin K inhibitors.
    Barrett DG; Catalano JG; Deaton DN; Long ST; McFadyen RB; Miller AB; Miller LR; Samano V; Tavares FX; Wells-Knecht KJ; Wright LL; Zhou HQ
    Bioorg Med Chem Lett; 2007 Jan; 17(1):22-7. PubMed ID: 17157021
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design and synthesis of calpain inhibitory 6-pyridone 2-carboxamide derivatives.
    Lee KY; Lee KS; Jin C; Lee YS
    Eur J Med Chem; 2009 Mar; 44(3):1331-4. PubMed ID: 18396356
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.