350 related articles for article (PubMed ID: 15928087)
1. The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1).
Garcia-Calvo M; Lisnock J; Bull HG; Hawes BE; Burnett DA; Braun MP; Crona JH; Davis HR; Dean DC; Detmers PA; Graziano MP; Hughes M; Macintyre DE; Ogawa A; O'neill KA; Iyer SP; Shevell DE; Smith MM; Tang YS; Makarewicz AM; Ujjainwalla F; Altmann SW; Chapman KT; Thornberry NA
Proc Natl Acad Sci U S A; 2005 Jun; 102(23):8132-7. PubMed ID: 15928087
[TBL] [Abstract][Full Text] [Related]
2. Bean peptides have higher in silico binding affinities than ezetimibe for the N-terminal domain of cholesterol receptor Niemann-Pick C1 Like-1.
Real Hernandez LM; Gonzalez de Mejia E
Peptides; 2017 Apr; 90():83-89. PubMed ID: 28259659
[TBL] [Abstract][Full Text] [Related]
3. Modulation of lipid metabolism with the overexpression of NPC1L1 in mouse liver.
Kurano M; Hara M; Tsuneyama K; Okamoto K; Iso-O N; Matsushima T; Koike K; Tsukamoto K
J Lipid Res; 2012 Nov; 53(11):2275-85. PubMed ID: 22891292
[TBL] [Abstract][Full Text] [Related]
4. The N-terminal domain of NPC1L1 protein binds cholesterol and plays essential roles in cholesterol uptake.
Zhang JH; Ge L; Qi W; Zhang L; Miao HH; Li BL; Yang M; Song BL
J Biol Chem; 2011 Jul; 286(28):25088-97. PubMed ID: 21602275
[TBL] [Abstract][Full Text] [Related]
5. Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins.
Saha P; Shumate JL; Caldwell JG; Elghobashi-Meinhardt N; Lu A; Zhang L; Olsson NE; Elias JE; Pfeffer SR
Elife; 2020 May; 9():. PubMed ID: 32410728
[TBL] [Abstract][Full Text] [Related]
6. Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake.
Ferrari A; Whang E; Xiao X; Kennelly JP; Romartinez-Alonso B; Mack JJ; Weston T; Chen K; Kim Y; Tol MJ; Bideyan L; Nguyen A; Gao Y; Cui L; Bedard AH; Sandhu J; Lee SD; Fairall L; Williams KJ; Song W; Munguia P; Russell RA; Martin MG; Jung ME; Jiang H; Schwabe JWR; Young SG; Tontonoz P
Science; 2023 Nov; 382(6671):eadf0966. PubMed ID: 37943936
[TBL] [Abstract][Full Text] [Related]
7. Bile acids-mediated intracellular cholesterol transport promotes intestinal cholesterol absorption and NPC1L1 recycling.
Xiao J; Dong LW; Liu S; Meng FH; Xie C; Lu XY; Zhang WJ; Luo J; Song BL
Nat Commun; 2023 Oct; 14(1):6469. PubMed ID: 37833289
[TBL] [Abstract][Full Text] [Related]
8. Entry of hepatitis C virus into the cell: a therapeutic target.
Del Campo JA; Rojas Á; Romero-Gómez M
World J Gastroenterol; 2012 Sep; 18(33):4481-5. PubMed ID: 22969220
[TBL] [Abstract][Full Text] [Related]
9. Aster-dependent non-vesicular transport facilitates dietary cholesterol uptake.
Ferrari A; Whang E; Xiao X; Kennelly JP; Romartinez-Alonso B; Mack JJ; Weston T; Chen K; Kim Y; Tol MJ; Bideyan L; Nguyen A; Gao Y; Cui L; Bedard AH; Sandhu J; Lee SD; Fairall L; Williams KJ; Song W; Munguia P; Russell RA; Martin MG; Jung ME; Jiang H; Schwabe JWR; Young SG; Tontonoz P
bioRxiv; 2023 Jul; ():. PubMed ID: 37503112
[TBL] [Abstract][Full Text] [Related]
10. Impact of micelle characteristics on cholesterol absorption and ezetimibe inhibition: Insights from Niemann-Pick C1-like 1 binding and molecular structure.
Aizawa H
J Liposome Res; 2023 Oct; ():1-13. PubMed ID: 37905576
[TBL] [Abstract][Full Text] [Related]
11. Mechanisms of Niemann-Pick type C1 Like 1 protein degradation in intestinal epithelial cells.
Malhotra P; Soni V; Yamanashi Y; Takada T; Suzuki H; Gill RK; Saksena S; Dudeja PK; Alrefai WA
Am J Physiol Cell Physiol; 2019 Apr; 316(4):C559-C566. PubMed ID: 30789754
[TBL] [Abstract][Full Text] [Related]
12. Binding of Cholesterol to the N-Terminal Domain of the NPC1L1 Transporter: Analysis of the Epimerization-Related Binding Selectivity and Loop Mutations.
Valdivia A; Luque FJ; Llabrés S
J Chem Inf Model; 2024 Jan; 64(1):189-204. PubMed ID: 38152929
[TBL] [Abstract][Full Text] [Related]
13. Visualization of lipid metabolism in the zebrafish intestine reveals a relationship between NPC1L1-mediated cholesterol uptake and dietary fatty acid.
Walters JW; Anderson JL; Bittman R; Pack M; Farber SA
Chem Biol; 2012 Jul; 19(7):913-25. PubMed ID: 22749558
[TBL] [Abstract][Full Text] [Related]
14. NPC1L1 Plays a Novel Role in Nonalcoholic Fatty Liver Disease.
Xu C; Fu F; She Y; Xu C
ACS Omega; 2023 Dec; 8(51):48586-48589. PubMed ID: 38162748
[TBL] [Abstract][Full Text] [Related]
15. Docking study of novel antihyperlipidemic thieno[2,3-d]pyrimidine; LM-1554, with some molecular targets related to hyperlipidemia - an investigation into its mechanism of action.
Khedkar VM; Arya N; Coutinho EC; Shishoo CJ; Jain KS
Springerplus; 2014; 3():628. PubMed ID: 25392798
[TBL] [Abstract][Full Text] [Related]
16. Zetia: inhibition of Niemann-Pick C1 Like 1 (NPC1L1) to reduce intestinal cholesterol absorption and treat hyperlipidemia.
Davis HR; Veltri EP
J Atheroscler Thromb; 2007 Jun; 14(3):99-108. PubMed ID: 17587760
[TBL] [Abstract][Full Text] [Related]
17. Niemann-pick C1-like 1 (NPC1L1) protein in intestinal and hepatic cholesterol transport.
Jia L; Betters JL; Yu L
Annu Rev Physiol; 2011; 73():239-59. PubMed ID: 20809793
[TBL] [Abstract][Full Text] [Related]
18. Extracellular loop C of NPC1L1 is important for binding to ezetimibe.
Weinglass AB; Kohler M; Schulte U; Liu J; Nketiah EO; Thomas A; Schmalhofer W; Williams B; Bildl W; McMasters DR; Dai K; Beers L; McCann ME; Kaczorowski GJ; Garcia ML
Proc Natl Acad Sci U S A; 2008 Aug; 105(32):11140-5. PubMed ID: 18682566
[TBL] [Abstract][Full Text] [Related]
19. The structure of the NPC1L1 N-terminal domain in a closed conformation.
Kwon HJ; Palnitkar M; Deisenhofer J
PLoS One; 2011 Apr; 6(4):e18722. PubMed ID: 21525977
[TBL] [Abstract][Full Text] [Related]
20.
; ; . PubMed ID:
[No Abstract] [Full Text] [Related]
[Next] [New Search]