123 related articles for article (PubMed ID: 15934785)
1. hPEPT1 affinity and translocation of selected Gln-Sar and Glu-Sar dipeptide derivatives.
Eriksson AH; Elm PL; Begtrup M; Nielsen R; Steffansen B; Brodin B
Mol Pharm; 2005; 2(3):242-9. PubMed ID: 15934785
[TBL] [Abstract][Full Text] [Related]
2. Pyrimidine and nucleoside gamma-esters of L-Glu-Sar: synthesis, stability and interaction with hPEPT1.
Eriksson AH; Elm PL; Begtrup M; Brodin B; Nielsen R; Steffansen B
Eur J Pharm Sci; 2005 May; 25(1):145-54. PubMed ID: 15854810
[TBL] [Abstract][Full Text] [Related]
3. Dipeptide model prodrugs for the intestinal oligopeptide transporter. Affinity for and transport via hPepT1 in the human intestinal Caco-2 cell line.
Nielsen CU; Andersen R; Brodin B; Frokjaer S; Taub ME; Steffansen B
J Control Release; 2001 Sep; 76(1-2):129-38. PubMed ID: 11532319
[TBL] [Abstract][Full Text] [Related]
4. Affinity and translocation relationships via hPEPT1 of H-X aa-Ser-OH dipeptides: evaluation of H-Phe-Ser-OH as a pro-moiety for ibuprofen and benzoic acid prodrugs.
Omkvist DH; Trangbæk DJ; Mildon J; Paine JS; Brodin B; Begtrup M; Nielsen CU
Eur J Pharm Biopharm; 2011 Feb; 77(2):327-31. PubMed ID: 21147219
[TBL] [Abstract][Full Text] [Related]
5. Cellular uptake mechanism of amino acid ester prodrugs in Caco-2/hPEPT1 cells overexpressing a human peptide transporter.
Han HK; Oh DM; Amidon GL
Pharm Res; 1998 Sep; 15(9):1382-6. PubMed ID: 9755889
[TBL] [Abstract][Full Text] [Related]
6. Prodrugs of purine and pyrimidine analogues for the intestinal di/tri-peptide transporter PepT1: affinity for hPepT1 in Caco-2 cells, drug release in aqueous media and in vitro metabolism.
Thomsen AE; Friedrichsen GM; Sørensen AH; Andersen R; Nielsen CU; Brodin B; Begtrup M; Frokjaer S; Steffansen B
J Control Release; 2003 Jan; 86(2-3):279-92. PubMed ID: 12526824
[TBL] [Abstract][Full Text] [Related]
7. Dipeptide derivatives of AZT: synthesis, chemical stability, activation in human plasma, hPEPT1 affinity, and antiviral activity.
Santos C; Morais J; Gouveia L; de Clercq E; Pannecouque C; Nielsen CU; Steffansen B; Moreira R; Gomes P
ChemMedChem; 2008 Jun; 3(6):970-8. PubMed ID: 18389514
[TBL] [Abstract][Full Text] [Related]
8. In vitro evaluation of N-methyl amide tripeptidomimetics as substrates for the human intestinal di-/tri-peptide transporter hPEPT1.
Andersen R; Nielsen CU; Begtrup M; Jørgensen FS; Brodin B; Frokjaer S; Steffansen B
Eur J Pharm Sci; 2006 Jul; 28(4):325-35. PubMed ID: 16713701
[TBL] [Abstract][Full Text] [Related]
9. Molecular interactions between dipeptides, drugs and the human intestinal H+ -oligopeptide cotransporter hPEPT1.
Sala-Rabanal M; Loo DD; Hirayama BA; Turk E; Wright EM
J Physiol; 2006 Jul; 574(Pt 1):149-66. PubMed ID: 16627568
[TBL] [Abstract][Full Text] [Related]
10. A quantitative structure-activity relationship for translocation of tripeptides via the human proton-coupled peptide transporter, hPEPT1 (SLC15A1).
Omkvist DH; Larsen SB; Nielsen CU; Steffansen B; Olsen L; Jørgensen FS; Brodin B
AAPS J; 2010 Sep; 12(3):385-96. PubMed ID: 20449699
[TBL] [Abstract][Full Text] [Related]
11. Serine side chain-linked peptidomimetic conjugates of cyclic HPMPC and HPMPA: synthesis and interaction with hPEPT1.
Peterson LW; Sala-Rabanal M; Krylov IS; Serpi M; Kashemirov BA; McKenna CE
Mol Pharm; 2010 Dec; 7(6):2349-61. PubMed ID: 20929265
[TBL] [Abstract][Full Text] [Related]
12. Substrate upregulation of the human small intestinal peptide transporter, hPepT1.
Walker D; Thwaites DT; Simmons NL; Gilbert HJ; Hirst BH
J Physiol; 1998 Mar; 507 ( Pt 3)(Pt 3):697-706. PubMed ID: 9508831
[TBL] [Abstract][Full Text] [Related]
13. Interactions of the dipeptide ester prodrugs of acyclovir with the intestinal oligopeptide transporter: competitive inhibition of glycylsarcosine transport in human intestinal cell line-Caco-2.
Anand BS; Patel J; Mitra AK
J Pharmacol Exp Ther; 2003 Feb; 304(2):781-91. PubMed ID: 12538834
[TBL] [Abstract][Full Text] [Related]
14. Application of enzymatically stable dipeptides for enhancement of intestinal permeability. Synthesis and in vitro evaluation of dipeptide-coupled compounds.
Friedrichsen GM; Jakobsen P; Taub M; Begtrup M
Bioorg Med Chem; 2001 Oct; 9(10):2625-32. PubMed ID: 11557350
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis, and evaluation of tripeptidic promoieties targeting the intestinal peptide transporter hPEPT1.
Thorn K; Andersen R; Christensen J; Jakobsen P; Nielsen CU; Steffansen B; Begtrup M
ChemMedChem; 2007 Apr; 2(4):479-87. PubMed ID: 17407174
[TBL] [Abstract][Full Text] [Related]
16. Epidermal growth factor and insulin short-term increase hPepT1-mediated glycylsarcosine uptake in Caco-2 cells.
Nielsen CU; Amstrup J; Nielsen R; Steffansen B; Frokjaer S; Brodin B
Acta Physiol Scand; 2003 Jun; 178(2):139-48. PubMed ID: 12780388
[TBL] [Abstract][Full Text] [Related]
17. Dipeptidomimetic ketomethylene isosteres as pro-moieties for drug transport via the human intestinal di-/tripeptide transporter hPEPT1: design, synthesis, stability, and biological investigations.
Våbenø J; Nielsen CU; Ingebrigtsen T; Lejon T; Steffansen B; Luthman K
J Med Chem; 2004 Sep; 47(19):4755-65. PubMed ID: 15341490
[TBL] [Abstract][Full Text] [Related]
18. Analysis of transmembrane segment 7 of the dipeptide transporter hPepT1 by cysteine-scanning mutagenesis.
Kulkarni AA; Haworth IS; Uchiyama T; Lee VH
J Biol Chem; 2003 Dec; 278(51):51833-40. PubMed ID: 14532279
[TBL] [Abstract][Full Text] [Related]
19. Ethanol inhibits functional activity of the human intestinal dipeptide transporter hPepT1 expressed in Xenopus oocytes.
Li K; Xu L; Kulkarni AA; Perkins DI; Haworth IS; Davies DL
Alcohol Clin Exp Res; 2008 May; 32(5):777-84. PubMed ID: 18336632
[TBL] [Abstract][Full Text] [Related]
20. Amino acid ester prodrugs of the antiviral agent 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole as potential substrates of hPEPT1 transporter.
Song X; Vig BS; Lorenzi PL; Drach JC; Townsend LB; Amidon GL
J Med Chem; 2005 Feb; 48(4):1274-7. PubMed ID: 15715497
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
