These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
1554 related articles for article (PubMed ID: 15936948)
1. Phosphorylation of amyloid precursor carboxy-terminal fragments enhances their processing by a gamma-secretase-dependent mechanism. Vingtdeux V; Hamdane M; Gompel M; Bégard S; Drobecq H; Ghestem A; Grosjean ME; Kostanjevecki V; Grognet P; Vanmechelen E; Buée L; Delacourte A; Sergeant N Neurobiol Dis; 2005 Nov; 20(2):625-37. PubMed ID: 15936948 [TBL] [Abstract][Full Text] [Related]
2. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets. Evin G; Zhu A; Holsinger RM; Masters CL; Li QX J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315 [TBL] [Abstract][Full Text] [Related]
3. gamma-Secretase can cleave amyloid precursor protein fragments independent of alpha- and beta-secretase pre-cutting. Kume H; Sekijima Y; Maruyama K; Kametani F Int J Mol Med; 2003 Jul; 12(1):57-60. PubMed ID: 12792809 [TBL] [Abstract][Full Text] [Related]
4. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi. Xia W; Zhang J; Ostaszewski BL; Kimberly WT; Seubert P; Koo EH; Shen J; Selkoe DJ Biochemistry; 1998 Nov; 37(47):16465-71. PubMed ID: 9843412 [TBL] [Abstract][Full Text] [Related]
5. Familial Alzheimer's disease mutations inhibit gamma-secretase-mediated liberation of beta-amyloid precursor protein carboxy-terminal fragment. Wiley JC; Hudson M; Kanning KC; Schecterson LC; Bothwell M J Neurochem; 2005 Sep; 94(5):1189-201. PubMed ID: 15992373 [TBL] [Abstract][Full Text] [Related]
6. Atorvastatin-induced activation of Alzheimer's alpha secretase is resistant to standard inhibitors of protein phosphorylation-regulated ectodomain shedding. Parvathy S; Ehrlich M; Pedrini S; Diaz N; Refolo L; Buxbaum JD; Bogush A; Petanceska S; Gandy S J Neurochem; 2004 Aug; 90(4):1005-10. PubMed ID: 15287907 [TBL] [Abstract][Full Text] [Related]
7. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity. Wolfe MS; Xia W; Ostaszewski BL; Diehl TS; Kimberly WT; Selkoe DJ Nature; 1999 Apr; 398(6727):513-7. PubMed ID: 10206644 [TBL] [Abstract][Full Text] [Related]
8. Truncated carboxyl-terminal fragments of beta-amyloid precursor protein are processed to amyloid beta-proteins 40 and 42. Funamoto S; Morishima-Kawashima M; Tanimura Y; Hirotani N; Saido TC; Ihara Y Biochemistry; 2004 Oct; 43(42):13532-40. PubMed ID: 15491160 [TBL] [Abstract][Full Text] [Related]
9. Processing of the Alzheimer's disease amyloid precursor protein in Pichia pastoris: immunodetection of alpha-, beta-, and gamma-secretase products. Le Brocque D; Henry A; Cappai R; Li QX; Tanner JE; Galatis D; Gray C; Holmes S; Underwood JR; Beyreuther K; Masters CL; Evin G Biochemistry; 1998 Oct; 37(42):14958-65. PubMed ID: 9778373 [TBL] [Abstract][Full Text] [Related]
10. FAD mutations in presenilin-1 or amyloid precursor protein decrease the efficacy of a gamma-secretase inhibitor: evidence for direct involvement of PS1 in the gamma-secretase cleavage complex. Xia W; Ostaszewski BL; Kimberly WT; Rahmati T; Moore CL; Wolfe MS; Selkoe DJ Neurobiol Dis; 2000 Dec; 7(6 Pt B):673-81. PubMed ID: 11114265 [TBL] [Abstract][Full Text] [Related]
11. Excess of nicastrin in brain results in heterozygosity having no effect on endogenous APP processing and amyloid peptide levels in vivo. Brijbassi S; Amtul Z; Newbigging S; Westaway D; St George-Hyslop P; Rozmahel RF Neurobiol Dis; 2007 Feb; 25(2):291-6. PubMed ID: 17071095 [TBL] [Abstract][Full Text] [Related]
12. Mechanism of gamma-secretase cleavage activation: is gamma-secretase regulated through autoinhibition involving the presenilin-1 exon 9 loop? Knappenberger KS; Tian G; Ye X; Sobotka-Briner C; Ghanekar SV; Greenberg BD; Scott CW Biochemistry; 2004 May; 43(20):6208-18. PubMed ID: 15147205 [TBL] [Abstract][Full Text] [Related]
13. CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide production. Zhou S; Zhou H; Walian PJ; Jap BK Proc Natl Acad Sci U S A; 2005 May; 102(21):7499-504. PubMed ID: 15890777 [TBL] [Abstract][Full Text] [Related]
14. In vitro gamma-secretase cleavage of the Alzheimer's amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc. Hoke DE; Tan JL; Ilaya NT; Culvenor JG; Smith SJ; White AR; Masters CL; Evin GM FEBS J; 2005 Nov; 272(21):5544-57. PubMed ID: 16262694 [TBL] [Abstract][Full Text] [Related]
15. Presenilins are required for gamma-secretase cleavage of beta-APP and transmembrane cleavage of Notch-1. Zhang Z; Nadeau P; Song W; Donoviel D; Yuan M; Bernstein A; Yankner BA Nat Cell Biol; 2000 Jul; 2(7):463-5. PubMed ID: 10878814 [No Abstract] [Full Text] [Related]
16. Intracellular generation of amyloid beta-protein from amyloid beta-protein precursor fragment by direct cleavage with beta- and gamma-secretase. Iizuka T; Shoji M; Kawarabayashi T; Sato M; Kobayashi T; Tada N; Kasai K; Matsubara E; Watanabe M; Tomidokoro Y; Hirai S Biochem Biophys Res Commun; 1996 Jan; 218(1):238-42. PubMed ID: 8573139 [TBL] [Abstract][Full Text] [Related]
17. Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein. De Strooper B; Saftig P; Craessaerts K; Vanderstichele H; Guhde G; Annaert W; Von Figura K; Van Leuven F Nature; 1998 Jan; 391(6665):387-90. PubMed ID: 9450754 [TBL] [Abstract][Full Text] [Related]
18. Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease beta-amyloid protein precursor: effect of C-terminal truncation on production of beta-amyloid protein. Nunan J; Williamson NA; Hill AF; Sernee MF; Masters CL; Small DH J Neurosci Res; 2003 Nov; 74(3):378-85. PubMed ID: 14598314 [TBL] [Abstract][Full Text] [Related]
19. A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain. De Strooper B; Annaert W; Cupers P; Saftig P; Craessaerts K; Mumm JS; Schroeter EH; Schrijvers V; Wolfe MS; Ray WJ; Goate A; Kopan R Nature; 1999 Apr; 398(6727):518-22. PubMed ID: 10206645 [TBL] [Abstract][Full Text] [Related]
20. Notch and the amyloid precursor protein are cleaved by similar gamma-secretase(s). Kimberly WT; Esler WP; Ye W; Ostaszewski BL; Gao J; Diehl T; Selkoe DJ; Wolfe MS Biochemistry; 2003 Jan; 42(1):137-44. PubMed ID: 12515548 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]