These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

102 related articles for article (PubMed ID: 15946819)

  • 1. Classification of drugs in absorption classes using the classification and regression trees (CART) methodology.
    Deconinck E; Hancock T; Coomans D; Massart DL; Heyden YV
    J Pharm Biomed Anal; 2005 Sep; 39(1-2):91-103. PubMed ID: 15946819
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prediction of gastro-intestinal absorption using multivariate adaptive regression splines.
    Deconinck E; Xu QS; Put R; Coomans D; Massart DL; Vander Heyden Y
    J Pharm Biomed Anal; 2005 Oct; 39(5):1021-30. PubMed ID: 16040225
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Baert B; Deconinck E; Van Gele M; Slodicka M; Stoppie P; Bodé S; Slegers G; Vander Heyden Y; Lambert J; Beetens J; De Spiegeleer B
    Bioorg Med Chem; 2007 Nov; 15(22):6943-55. PubMed ID: 17827020
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ADME evaluation in drug discovery. 5. Correlation of Caco-2 permeation with simple molecular properties.
    Hou TJ; Zhang W; Xia K; Qiao XB; Xu XJ
    J Chem Inf Comput Sci; 2004; 44(5):1585-600. PubMed ID: 15446816
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Quantitative structure-property relationship study of n-octanol-water partition coefficients of some of diverse drugs using multiple linear regression.
    Ghasemi J; Saaidpour S
    Anal Chim Acta; 2007 Dec; 604(2):99-106. PubMed ID: 17996529
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Orthogonal chromatographic descriptors for modelling Caco-2 drug permeability.
    Deconinck E; Verstraete T; Van Gyseghem E; Vander Heyden Y; Coomans D
    J Chromatogr Sci; 2012 Mar; 50(3):175-83. PubMed ID: 22337793
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Using general regression and probabilistic neural networks to predict human intestinal absorption with topological descriptors derived from two-dimensional chemical structures.
    Niwa T
    J Chem Inf Comput Sci; 2003; 43(1):113-9. PubMed ID: 12546543
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Predicting MDCK cell permeation coefficients of organic molecules using membrane-interaction QSAR analysis.
    Chen LL; Yao J; Yang JB; Yang J
    Acta Pharmacol Sin; 2005 Nov; 26(11):1322-33. PubMed ID: 16225754
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Quick prediction of the retention of solutes in 13 thin layer chromatographic screening systems on silica gel by classification and regression trees.
    Komsta Ł
    J Sep Sci; 2008 Aug; 31(15):2899-909. PubMed ID: 18655019
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ADME evaluation in drug discovery. 8. The prediction of human intestinal absorption by a support vector machine.
    Hou T; Wang J; Li Y
    J Chem Inf Model; 2007; 47(6):2408-15. PubMed ID: 17929911
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Prediction and mechanistic interpretation of human oral drug absorption using MI-QSAR analysis.
    Iyer M; Tseng YJ; Senese CL; Liu J; Hopfinger AJ
    Mol Pharm; 2007; 4(2):218-31. PubMed ID: 17397237
    [TBL] [Abstract][Full Text] [Related]  

  • 12. QSAR modeling of mono- and bis-quaternary ammonium salts that act as antagonists at neuronal nicotinic acetylcholine receptors mediating dopamine release.
    Zheng F; Bayram E; Sumithran SP; Ayers JT; Zhan CG; Schmitt JD; Dwoskin LP; Crooks PA
    Bioorg Med Chem; 2006 May; 14(9):3017-37. PubMed ID: 16431111
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Classification models for neocryptolepine derivatives as inhibitors of the β-haematin formation.
    Dejaegher B; Dhooghe L; Goodarzi M; Apers S; Pieters L; Vander Heyden Y
    Anal Chim Acta; 2011 Oct; 705(1-2):98-110. PubMed ID: 21962353
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Improvement of multivariate image analysis applied to quantitative structure-activity relationship (QSAR) analysis by using wavelet-principal component analysis ranking variable selection and least-squares support vector machine regression: QSAR study of checkpoint kinase WEE1 inhibitors.
    Cormanich RA; Goodarzi M; Freitas MP
    Chem Biol Drug Des; 2009 Feb; 73(2):244-52. PubMed ID: 19207427
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Exploration of linear modelling techniques and their combination with multivariate adaptive regression splines to predict gastro-intestinal absorption of drugs.
    Deconinck E; Coomans D; Vander Heyden Y
    J Pharm Biomed Anal; 2007 Jan; 43(1):119-30. PubMed ID: 16859855
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Computational prediction of oral drug absorption based on absorption rate constants in humans.
    Linnankoski J; Mäkelä JM; Ranta VP; Urtti A; Yliperttula M
    J Med Chem; 2006 Jun; 49(12):3674-81. PubMed ID: 16759110
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecule kernels: a descriptor- and alignment-free quantitative structure-activity relationship approach.
    Mohr JA; Jain BJ; Obermayer K
    J Chem Inf Model; 2008 Sep; 48(9):1868-81. PubMed ID: 18767832
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evaluation of chromatographic descriptors for the prediction of gastro-intestinal absorption of drugs.
    Deconinck E; Ates H; Callebaut N; Van Gyseghem E; Vander Heyden Y
    J Chromatogr A; 2007 Jan; 1138(1-2):190-202. PubMed ID: 17097093
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Predicting penetration across the blood-brain barrier from simple descriptors and fragmentation schemes.
    Zhao YH; Abraham MH; Ibrahim A; Fish PV; Cole S; Lewis ML; de Groot MJ; Reynolds DP
    J Chem Inf Model; 2007; 47(1):170-5. PubMed ID: 17238262
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Anticancer activity of selected phenolic compounds: QSAR studies using ridge regression and neural networks.
    Nandi S; Vracko M; Bagchi MC
    Chem Biol Drug Des; 2007 Nov; 70(5):424-36. PubMed ID: 17949360
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.