BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

66 related articles for article (PubMed ID: 15949707)

  • 1. Comparison of the properties of rare variants of alpha1-proteinase inhibitor expressed in COS-1 cells and assessment of their potential as risk factors in human disease.
    Ray S; Mickleborough TD; Brown JL
    Biochim Biophys Acta; 2005 Jun; 1740(3):390-402. PubMed ID: 15949707
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A study of the effects of altering the sites for N-glycosylation in alpha-1-proteinase inhibitor variants M and S.
    Samandari T; Brown JL
    Protein Sci; 1993 Sep; 2(9):1400-10. PubMed ID: 8401226
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Construction and expression of alpha 1-proteinase inhibitor mutants and the effects of these mutations on secretion of the variant inhibitors.
    McCracken AA; Kruse KB; Valentine J; Roberts C; Yohannes TZ; Brown JL
    J Biol Chem; 1991 Apr; 266(12):7578-82. PubMed ID: 2019587
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Single amino acid substitutions in recombinant plant-derived human α1-proteinase inhibitor confer enhanced stability and functional efficacy.
    Jha S; Sanyal I; Amla DV
    Biochim Biophys Acta; 2014 Jan; 1840(1):416-27. PubMed ID: 24090883
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Secretion of alpha-1-proteinase inhibitor requires an almost full length molecule.
    Brodbeck RM; Brown JL
    J Biol Chem; 1992 Jan; 267(1):294-7. PubMed ID: 1730596
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Expression and purification of recombinant human alpha1-proteinase inhibitor and its single amino acid substituted variants in Escherichia coli for enhanced stability and biological activity.
    Agarwal S; Jha S; Sanyal I; Amla DV
    J Biotechnol; 2010 May; 147(1):64-72. PubMed ID: 20346993
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Engineering of α1-antitrypsin variants with improved specificity for the proprotein convertase furin using site-directed random mutagenesis.
    Hada K; Isshiki K; Matsuda S; Yuasa K; Tsuji A
    Protein Eng Des Sel; 2013 Feb; 26(2):123-31. PubMed ID: 23155057
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional analysis of novel alpha-1 antitrypsin variants G320R and V321F.
    Ljujic M; Divac Rankov A; Kojic S; Miranda E; Radojkovic D
    Mol Biol Rep; 2014 Sep; 41(9):6133-41. PubMed ID: 24969485
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional analysis of the glaucoma-causing TIGR/myocilin protein: integrity of amino-terminal coiled-coil regions and olfactomedin homology domain is essential for extracellular adhesion and secretion.
    Gobeil S; Letartre L; Raymond V
    Exp Eye Res; 2006 Jun; 82(6):1017-29. PubMed ID: 16466712
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular characterisation of the defective alpha 1-antitrypsin alleles PI Mwurzburg (Pro369Ser), Mheerlen (Pro369Leu), and Q0lisbon (Thr68Ile).
    Poller W; Merklein F; Schneider-Rasp S; Haack A; Fechner H; Wang H; Anagnostopoulos I; Weidinger S
    Eur J Hum Genet; 1999 Apr; 7(3):321-31. PubMed ID: 10234508
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of mutations that alter the Glu264-Lys387 salt bridge on the secretion of alpha-1-proteinase inhibitor.
    Brodbeck RM; Samandari T; Brown JL
    J Biol Chem; 1993 Mar; 268(9):6771-6. PubMed ID: 8454649
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The P6-P2 region of serpins is critical for proteinase inhibition and complex stability.
    Chaillan-Huntington CE; Gettins PG; Huntington JA; Patston PA
    Biochemistry; 1997 Aug; 36(31):9562-70. PubMed ID: 9236002
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [The role of alpha(1)-proteinase inhibitor in developing hereditary pulmonary diseases].
    Pilipchuk VN; Serdiuk TM
    Probl Tuberk; 1991; (1):71-3. PubMed ID: 2034631
    [No Abstract]   [Full Text] [Related]  

  • 14. Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity.
    Hampe C; Ardila-Osorio H; Fournier M; Brice A; Corti O
    Hum Mol Genet; 2006 Jul; 15(13):2059-75. PubMed ID: 16714300
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression screening of bacterial libraries of recombinant alpha-1 proteinase inhibitor variants for candidates with thrombin inhibitory capacity.
    Bhakta V; Gierczak RF; Sheffield WP
    J Biotechnol; 2013 Dec; 168(4):373-81. PubMed ID: 24140600
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Intracellular processing of complement pro-C3 and proalbumin is inhibited by rat alpha 1-protease inhibitor variant (Met352----Arg) in transfected cells.
    Misumi Y; Ohkubo K; Sohda M; Takami N; Oda K; Ikehara Y
    Biochem Biophys Res Commun; 1990 Aug; 171(1):236-42. PubMed ID: 2393391
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fabry disease: characterization of alpha-galactosidase A double mutations and the D313Y plasma enzyme pseudodeficiency allele.
    Yasuda M; Shabbeer J; Benson SD; Maire I; Burnett RM; Desnick RJ
    Hum Mutat; 2003 Dec; 22(6):486-92. PubMed ID: 14635108
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Properties of the His57-Asp102 dyad of rat trypsin D189S in the zymogen, activated enzyme, and alpha1-proteinase inhibitor complexed forms.
    Kaslik G; Westler WM; Gráf L; Markley JL
    Arch Biochem Biophys; 1999 Feb; 362(2):254-64. PubMed ID: 9989934
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Heparin cofactor II is more sensitive than antithrombin to secretory impairment arising from mutations introduced into its carboxy-terminal region.
    Bhakta V; Begbie ME; Gupta A; Sandhu V; Sheffield WP
    Thromb Res; 2004; 113(2):163-73. PubMed ID: 15115672
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Polymerase chain reaction detection of S and Z alpha-1-antitrypsin variants by duplex PCR assay.
    Lucotte G; Sesboüé R
    Mol Cell Probes; 1999 Oct; 13(5):389-91. PubMed ID: 10508561
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.