These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Mechanism for transforming cytosolic SOD1 into integral membrane proteins of organelles by ALS-causing mutations. Lim L; Lee X; Song J Biochim Biophys Acta; 2015 Jan; 1848(1 Pt A):1-7. PubMed ID: 25306968 [TBL] [Abstract][Full Text] [Related]
4. Structure, folding, and misfolding of Cu,Zn superoxide dismutase in amyotrophic lateral sclerosis. Rakhit R; Chakrabartty A Biochim Biophys Acta; 2006; 1762(11-12):1025-37. PubMed ID: 16814528 [TBL] [Abstract][Full Text] [Related]
5. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1. Jaarsma D; Haasdijk ED; Grashorn JA; Hawkins R; van Duijn W; Verspaget HW; London J; Holstege JC Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261 [TBL] [Abstract][Full Text] [Related]
6. Zinc and copper in the pathogenesis of amyotrophic lateral sclerosis. Elliott JL Prog Neuropsychopharmacol Biol Psychiatry; 2001 Aug; 25(6):1169-85. PubMed ID: 11474839 [TBL] [Abstract][Full Text] [Related]
7. An intersubunit disulfide bond prevents in vitro aggregation of a superoxide dismutase-1 mutant linked to familial amytrophic lateral sclerosis. Ray SS; Nowak RJ; Strokovich K; Brown RH; Walz T; Lansbury PT Biochemistry; 2004 May; 43(17):4899-905. PubMed ID: 15109247 [TBL] [Abstract][Full Text] [Related]
8. Increased affinity for copper mediated by cysteine 111 in forms of mutant superoxide dismutase 1 linked to amyotrophic lateral sclerosis. Watanabe S; Nagano S; Duce J; Kiaei M; Li QX; Tucker SM; Tiwari A; Brown RH; Beal MF; Hayward LJ; Culotta VC; Yoshihara S; Sakoda S; Bush AI Free Radic Biol Med; 2007 May; 42(10):1534-42. PubMed ID: 17448900 [TBL] [Abstract][Full Text] [Related]
9. Superoxide dismutase mutations of familial amyotrophic lateral sclerosis and the oxidative inactivation of calcineurin. Volkel H; Scholz M; Link J; Selzle M; Werner P; Tunnemann R; Jung G; Ludolph AC; Reuter A FEBS Lett; 2001 Aug; 503(2-3):201-5. PubMed ID: 11513882 [TBL] [Abstract][Full Text] [Related]
10. Metalation of the amyotrophic lateral sclerosis mutant glycine 37 to arginine superoxide dismutase (SOD1) apoprotein restores its structural and dynamical properties in solution to those of metalated wild-type SOD1. Banci L; Bertini I; D'Amelio N; Libralesso E; Turano P; Valentine JS Biochemistry; 2007 Sep; 46(35):9953-62. PubMed ID: 17683122 [TBL] [Abstract][Full Text] [Related]
11. Common dynamical signatures of familial amyotrophic lateral sclerosis-associated structurally diverse Cu, Zn superoxide dismutase mutants. Khare SD; Dokholyan NV Proc Natl Acad Sci U S A; 2006 Feb; 103(9):3147-52. PubMed ID: 16488975 [TBL] [Abstract][Full Text] [Related]
12. Small-molecule-mediated stabilization of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants against unfolding and aggregation. Ray SS; Nowak RJ; Brown RH; Lansbury PT Proc Natl Acad Sci U S A; 2005 Mar; 102(10):3639-44. PubMed ID: 15738401 [TBL] [Abstract][Full Text] [Related]
13. FALS mutations in Cu, Zn superoxide dismutase destabilize the dimer and increase dimer dissociation propensity: a large-scale thermodynamic analysis. Khare SD; Caplow M; Dokholyan NV Amyloid; 2006 Dec; 13(4):226-35. PubMed ID: 17107883 [TBL] [Abstract][Full Text] [Related]
14. Comparative structural and conformational studies on H43R and W32F mutants of copper-zinc superoxide dismutase by molecular dynamics simulation. Muneeswaran G; Kartheeswaran S; Muthukumar K; Dharmaraj CD; Karunakaran C Biophys Chem; 2014 Jan; 185():70-8. PubMed ID: 24369116 [TBL] [Abstract][Full Text] [Related]
15. Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells. Rabizadeh S; Gralla EB; Borchelt DR; Gwinn R; Valentine JS; Sisodia S; Wong P; Lee M; Hahn H; Bredesen DE Proc Natl Acad Sci U S A; 1995 Mar; 92(7):3024-8. PubMed ID: 7708768 [TBL] [Abstract][Full Text] [Related]
16. Structural changes to monomeric CuZn superoxide dismutase caused by the familial amyotrophic lateral sclerosis-associated mutation A4V. Schmidlin T; Kennedy BK; Daggett V Biophys J; 2009 Sep; 97(6):1709-18. PubMed ID: 19751676 [TBL] [Abstract][Full Text] [Related]
17. Reduced reactivation rate in mutant CuZnSOD and progression rate of amyotrophic lateral sclerosis. Völkel H; Selzle M; Walk T; Jung G; Link J; Ludolph AC; Reuter A Eur J Neurol; 2004 Jun; 11(6):397-404. PubMed ID: 15171736 [TBL] [Abstract][Full Text] [Related]
18. The Disulfide Bond, but Not Zinc or Dimerization, Controls Initiation and Seeded Growth in Amyotrophic Lateral Sclerosis-linked Cu,Zn Superoxide Dismutase (SOD1) Fibrillation. Chattopadhyay M; Nwadibia E; Strong CD; Gralla EB; Valentine JS; Whitelegge JP J Biol Chem; 2015 Dec; 290(51):30624-36. PubMed ID: 26511321 [TBL] [Abstract][Full Text] [Related]
19. Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS. Banci L; Bertini I; Durazo A; Girotto S; Gralla EB; Martinelli M; Valentine JS; Vieru M; Whitelegge JP Proc Natl Acad Sci U S A; 2007 Jul; 104(27):11263-7. PubMed ID: 17592131 [TBL] [Abstract][Full Text] [Related]
20. How do ALS-associated mutations in superoxide dismutase 1 promote aggregation of the protein? Shaw BF; Valentine JS Trends Biochem Sci; 2007 Feb; 32(2):78-85. PubMed ID: 17208444 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]