324 related articles for article (PubMed ID: 15956280)
1. Dual targeting of transformed and untransformed HTLV-1-infected T cells by DHMEQ, a potent and selective inhibitor of NF-kappaB, as a strategy for chemoprevention and therapy of adult T-cell leukemia.
Watanabe M; Ohsugi T; Shoda M; Ishida T; Aizawa S; Maruyama-Nagai M; Utsunomiya A; Koga S; Yamada Y; Kamihira S; Okayama A; Kikuchi H; Uozumi K; Yamaguchi K; Higashihara M; Umezawa K; Watanabe T; Horie R
Blood; 2005 Oct; 106(7):2462-71. PubMed ID: 15956280
[TBL] [Abstract][Full Text] [Related]
2. Dehydroxymethylepoxyquinomicin (DHMEQ) therapy reduces tumor formation in mice inoculated with tax-deficient adult T-cell leukemia-derived cell lines.
Ohsugi T; Kumasaka T; Okada S; Ishida T; Yamaguchi K; Horie R; Watanabe T; Umezawa K
Cancer Lett; 2007 Nov; 257(2):206-15. PubMed ID: 17764832
[TBL] [Abstract][Full Text] [Related]
3. Blocking NF-kappaB as a potential strategy to treat adult T-cell leukemia/lymphoma.
Horie R; Watanabe T; Umezawa K
Drug News Perspect; 2006 May; 19(4):201-9. PubMed ID: 16823495
[TBL] [Abstract][Full Text] [Related]
4. In vivo antitumor activity of the NF-kappaB inhibitor dehydroxymethylepoxyquinomicin in a mouse model of adult T-cell leukemia.
Ohsugi T; Horie R; Kumasaka T; Ishida A; Ishida T; Yamaguchi K; Watanabe T; Umezawa K; Urano T
Carcinogenesis; 2005 Aug; 26(8):1382-8. PubMed ID: 15831528
[TBL] [Abstract][Full Text] [Related]
5. Curcumin (diferuloylmethane) inhibits constitutive active NF-kappaB, leading to suppression of cell growth of human T-cell leukemia virus type I-infected T-cell lines and primary adult T-cell leukemia cells.
Tomita M; Kawakami H; Uchihara JN; Okudaira T; Masuda M; Takasu N; Matsuda T; Ohta T; Tanaka Y; Ohshiro K; Mori N
Int J Cancer; 2006 Feb; 118(3):765-72. PubMed ID: 16106398
[TBL] [Abstract][Full Text] [Related]
6. Induction of apoptosis in Epstein-Barr virus-infected B-lymphocytes by the NF-kappaB inhibitor DHMEQ.
Miyake A; Dewan MZ; Ishida T; Watanabe M; Honda M; Sata T; Yamamoto N; Umezawa K; Watanabe T; Horie R
Microbes Infect; 2008 Jun; 10(7):748-56. PubMed ID: 18538617
[TBL] [Abstract][Full Text] [Related]
7. A novel NF-kappaB inhibitor DHMEQ selectively targets constitutive NF-kappaB activity and induces apoptosis of multiple myeloma cells in vitro and in vivo.
Watanabe M; Dewan MZ; Okamura T; Sasaki M; Itoh K; Higashihara M; Mizoguchi H; Honda M; Sata T; Watanabe T; Yamamoto N; Umezawa K; Horie R
Int J Cancer; 2005 Mar; 114(1):32-8. PubMed ID: 15523684
[TBL] [Abstract][Full Text] [Related]
8. NIK-333 inhibits growth of human T-cell leukemia virus type I-infected T-cell lines and adult T-cell leukemia cells in association with blockade of nuclear factor-kappaB signal pathway.
Okudaira T; Tomita M; Uchihara JN; Matsuda T; Ishikawa C; Kawakami H; Masuda M; Tanaka Y; Ohshiro K; Takasu N; Mori N
Mol Cancer Ther; 2006 Mar; 5(3):704-12. PubMed ID: 16546985
[TBL] [Abstract][Full Text] [Related]
9. In vitro and in vivo antitumor activity of the NF-kappaB inhibitor DHMEQ in the human T-cell leukemia virus type I-infected cell line, HUT-102.
Ohsugi T; Kumasaka T; Ishida A; Ishida T; Horie R; Watanabe T; Umezawa K; Yamaguchi K
Leuk Res; 2006 Jan; 30(1):90-7. PubMed ID: 16002138
[TBL] [Abstract][Full Text] [Related]
10. Transient inhibition of NF-kappaB by DHMEQ induces cell death of primary effusion lymphoma without HHV-8 reactivation.
Dabaghmanesh N; Matsubara A; Miyake A; Nakano K; Ishida T; Katano H; Horie R; Umezawa K; Watanabe T
Cancer Sci; 2009 Apr; 100(4):737-46. PubMed ID: 19469019
[TBL] [Abstract][Full Text] [Related]
11. Targeting of nuclear factor kappaB Pathways by dehydroxymethylepoxyquinomicin, a novel inhibitor of breast carcinomas: antitumor and antiangiogenic potential in vivo.
Matsumoto G; Namekawa J; Muta M; Nakamura T; Bando H; Tohyama K; Toi M; Umezawa K
Clin Cancer Res; 2005 Feb; 11(3):1287-93. PubMed ID: 15709200
[TBL] [Abstract][Full Text] [Related]
12. Bay 11-7082 inhibits transcription factor NF-kappaB and induces apoptosis of HTLV-I-infected T-cell lines and primary adult T-cell leukemia cells.
Mori N; Yamada Y; Ikeda S; Yamasaki Y; Tsukasaki K; Tanaka Y; Tomonaga M; Yamamoto N; Fujii M
Blood; 2002 Sep; 100(5):1828-34. PubMed ID: 12176906
[TBL] [Abstract][Full Text] [Related]
13. Apoptosis induced by the histone deacetylase inhibitor FR901228 in human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells.
Mori N; Matsuda T; Tadano M; Kinjo T; Yamada Y; Tsukasaki K; Ikeda S; Yamasaki Y; Tanaka Y; Ohta T; Iwamasa T; Tomonaga M; Yamamoto N
J Virol; 2004 May; 78(9):4582-90. PubMed ID: 15078940
[TBL] [Abstract][Full Text] [Related]
14. p53 dysfunction precedes the activation of nuclear factor-κB during disease progression in mice expressing Tax, a human T-cell leukemia virus type 1 oncoprotein.
Ohsugi T; Ishida T; Shimasaki T; Okada S; Umezawa K
Carcinogenesis; 2013 Sep; 34(9):2129-36. PubMed ID: 23633516
[TBL] [Abstract][Full Text] [Related]
15. Fucoidan extracted from Cladosiphon okamuranus Tokida induces apoptosis of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells.
Haneji K; Matsuda T; Tomita M; Kawakami H; Ohshiro K; Uchihara JN; Masuda M; Takasu N; Tanaka Y; Ohta T; Mori N
Nutr Cancer; 2005; 52(2):189-201. PubMed ID: 16201850
[TBL] [Abstract][Full Text] [Related]
16. Rapid tumor formation of human T-cell leukemia virus type 1-infected cell lines in novel NOD-SCID/gammac(null) mice: suppression by an inhibitor against NF-kappaB.
Dewan MZ; Terashima K; Taruishi M; Hasegawa H; Ito M; Tanaka Y; Mori N; Sata T; Koyanagi Y; Maeda M; Kubuki Y; Okayama A; Fujii M; Yamamoto N
J Virol; 2003 May; 77(9):5286-94. PubMed ID: 12692230
[TBL] [Abstract][Full Text] [Related]
17. Dehydroxymethylepoxyquinomicin, a novel nuclear factor-kappaB inhibitor, induces apoptosis in multiple myeloma cells in an IkappaBalpha-independent manner.
Tatetsu H; Okuno Y; Nakamura M; Matsuno F; Sonoki T; Taniguchi I; Uneda S; Umezawa K; Mitsuya H; Hata H
Mol Cancer Ther; 2005 Jul; 4(7):1114-20. PubMed ID: 16020669
[TBL] [Abstract][Full Text] [Related]
18. DHMEQ, a new NF-kappaB inhibitor, induces apoptosis and enhances fludarabine effects on chronic lymphocytic leukemia cells.
Horie R; Watanabe M; Okamura T; Taira M; Shoda M; Motoji T; Utsunomiya A; Watanabe T; Higashihara M; Umezawa K
Leukemia; 2006 May; 20(5):800-6. PubMed ID: 16525497
[TBL] [Abstract][Full Text] [Related]
19. Antitumor effects of dehydroxymethylepoxyquinomicin, a novel nuclear factor-kappaB inhibitor, in human liver cancer cells are mediated through a reactive oxygen species-dependent mechanism.
Lampiasi N; Azzolina A; D'Alessandro N; Umezawa K; McCubrey JA; Montalto G; Cervello M
Mol Pharmacol; 2009 Aug; 76(2):290-300. PubMed ID: 19461054
[TBL] [Abstract][Full Text] [Related]
20. IkappaBalpha independent induction of NF-kappaB and its inhibition by DHMEQ in Hodgkin/Reed-Sternberg cells.
Watanabe M; Dewan MZ; Taira M; Shoda M; Honda M; Sata T; Higashihara M; Kadin ME; Watanabe T; Yamamoto N; Umezawa K; Horie R
Lab Invest; 2007 Apr; 87(4):372-82. PubMed ID: 17310217
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
