These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
124 related articles for article (PubMed ID: 15969015)
1. [Construction of an anti-apoptosis CHO cell line for biopharmaceutical production]. Lai DZ; Fu L; Yu CM; Qi LQ; Weng SJ; Yu T; Wang HT; Chen W Sheng Wu Gong Cheng Xue Bao; 2003 May; 19(3):322-6. PubMed ID: 15969015 [TBL] [Abstract][Full Text] [Related]
2. Improving the efficiency of CHO cell line generation using glutamine synthetase gene knockout cells. Fan L; Kadura I; Krebs LE; Hatfield CC; Shaw MM; Frye CC Biotechnol Bioeng; 2012 Apr; 109(4):1007-15. PubMed ID: 22068567 [TBL] [Abstract][Full Text] [Related]
3. [Construction of two robust CHO cell lines resistant to apoptosis and adapted to protein-free medium by over-expression of Igf-1/bcl-2 or bcl-2/cyclin E genes]. Lai DZ; Weng SJ; Qi LQ; Yu CM; Fu L; Yu T; Chen W Sheng Wu Gong Cheng Xue Bao; 2004 Jan; 20(1):66-72. PubMed ID: 16108493 [TBL] [Abstract][Full Text] [Related]
4. Aven and Bcl-xL enhance protection against apoptosis for mammalian cells exposed to various culture conditions. Figueroa B; Chen S; Oyler GA; Hardwick JM; Betenbaugh MJ Biotechnol Bioeng; 2004 Mar; 85(6):589-600. PubMed ID: 14966800 [TBL] [Abstract][Full Text] [Related]
5. Combining high-throughput screening of caspase activity with anti-apoptosis genes for development of robust CHO production cell lines. Dorai H; Ellis D; Keung YS; Campbell M; Zhuang M; Lin C; Betenbaugh MJ Biotechnol Prog; 2010; 26(5):1367-81. PubMed ID: 20945491 [TBL] [Abstract][Full Text] [Related]
6. Development of a highly-efficient CHO cell line generation system with engineered SV40E promoter. Fan L; Kadura I; Krebs LE; Larson JL; Bowden DM; Frye CC J Biotechnol; 2013 Dec; 168(4):652-8. PubMed ID: 23994266 [TBL] [Abstract][Full Text] [Related]
7. Part I. Bcl-2 and Bcl-x(L) limit apoptosis upon infection with alphavirus vectors. Mastrangelo AJ; Hardwick JM; Bex F; Betenbaugh MJ Biotechnol Bioeng; 2000 Mar; 67(5):544-54. PubMed ID: 10649229 [TBL] [Abstract][Full Text] [Related]
8. Impact of coexpression and coamplification of sICAM and antiapoptosis determinants bcl-2/bcl-x(L) on productivity, cell survival, and mitochondria number in CHO-DG44 grown in suspension and serum-free media. Meents H; Enenkel B; Eppenberger HM; Werner RG; Fussenegger M Biotechnol Bioeng; 2002 Dec; 80(6):706-16. PubMed ID: 12378612 [TBL] [Abstract][Full Text] [Related]
9. Mcl-1 overexpression leads to higher viabilities and increased production of humanized monoclonal antibody in Chinese hamster ovary cells. Majors BS; Betenbaugh MJ; Pederson NE; Chiang GG Biotechnol Prog; 2009; 25(4):1161-8. PubMed ID: 19551877 [TBL] [Abstract][Full Text] [Related]
10. Regulation of cell proliferation and apoptosis in CHO-K1 cells by the coexpression of c-Myc and Bcl-2. Ifandi V; Al-Rubeai M Biotechnol Prog; 2005; 21(3):671-7. PubMed ID: 15932241 [TBL] [Abstract][Full Text] [Related]
11. Limitations to the development of humanized antibody producing Chinese hamster ovary cells using glutamine synthetase-mediated gene amplification. Jun SC; Kim MS; Hong HJ; Lee GM Biotechnol Prog; 2006; 22(3):770-80. PubMed ID: 16739961 [TBL] [Abstract][Full Text] [Related]
12. Early prediction of instability of Chinese hamster ovary cell lines expressing recombinant antibodies and antibody-fusion proteins. Dorai H; Corisdeo S; Ellis D; Kinney C; Chomo M; Hawley-Nelson P; Moore G; Betenbaugh MJ; Ganguly S Biotechnol Bioeng; 2012 Apr; 109(4):1016-30. PubMed ID: 22068683 [TBL] [Abstract][Full Text] [Related]
13. Effect of glutamine limitation on the death of attached Chinese hamster ovary cells. Sanfeliu A; Stephanopoulos G Biotechnol Bioeng; 1999 Jul; 64(1):46-53. PubMed ID: 10397838 [TBL] [Abstract][Full Text] [Related]
14. Blocking caspase-3 activity with a U6 SnRNA promoter-driven ribozyme enhances survivability of CHO cells cultured in low serum medium and production of interferon-beta. Lai D; Fu L; Weng S; Qi L; Yu C; Yu T; Wang H; Chen W Biotechnol Bioeng; 2004 Jan; 85(1):20-8. PubMed ID: 14705008 [TBL] [Abstract][Full Text] [Related]
15. [Peroxisome proliferator activated receptor gamma coactivator-1 induces apoptosis in human epithelial ovarian cancer cells]. Ba Y; Zhang Y; Zhang CY Zhonghua Yi Xue Za Zhi; 2007 May; 87(20):1430-3. PubMed ID: 17785072 [TBL] [Abstract][Full Text] [Related]
16. Enhancement of transient gene expression and culture viability using Chinese hamster ovary cells overexpressing Bcl-x(L). Majors BS; Betenbaugh MJ; Pederson NE; Chiang GG Biotechnol Bioeng; 2008 Oct; 101(3):567-78. PubMed ID: 18727128 [TBL] [Abstract][Full Text] [Related]
17. Attenuated glutamine synthetase as a selection marker in CHO cells to efficiently isolate highly productive stable cells for the production of antibodies and other biologics. Lin PC; Chan KF; Kiess IA; Tan J; Shahreel W; Wong SY; Song Z MAbs; 2019 Jul; 11(5):965-976. PubMed ID: 31043114 [TBL] [Abstract][Full Text] [Related]
18. [Modification of the antiapoptotic ability of H18 hybridoma cells]. Wang XH; Xu J; Zhang Y; Mi L; Chen ZN Sheng Wu Gong Cheng Xue Bao; 2003 Nov; 19(6):705-8. PubMed ID: 15971583 [TBL] [Abstract][Full Text] [Related]
19. Cisplatin-induced apoptosis proceeds by caspase-3-dependent and -independent pathways in cisplatin-resistant and -sensitive human ovarian cancer cell lines. Henkels KM; Turchi JJ Cancer Res; 1999 Jul; 59(13):3077-83. PubMed ID: 10397248 [TBL] [Abstract][Full Text] [Related]
20. [Construction of CHO-IVB, A serum-independent, apoptosis-resistant cell line that can grow in adherence]. Weng SJ; Lai DZ; Qi LQ; Yu CM; Fu L; Chen W Sheng Wu Gong Cheng Xue Bao; 2004 Sep; 20(5):745-9. PubMed ID: 15974002 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]