BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 15970518)

  • 1. Docetaxel induces p53-dependent apoptosis and synergizes with farnesyl transferase inhibitor r115777 in human epithelial cancer cells.
    Caraglia M; Giuberti G; Marra M; Di Gennaro E; Facchini G; Caponigro F; Iaffaioli R; Budillon A; Abbruzzese A
    Front Biosci; 2005 Sep; 10():2566-75. PubMed ID: 15970518
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The farnesyl transferase inhibitor R115777 (Zarnestra) synergistically enhances growth inhibition and apoptosis induced on epidermoid cancer cells by Zoledronic acid (Zometa) and Pamidronate.
    Caraglia M; D'Alessandro AM; Marra M; Giuberti G; Vitale G; Viscomi C; Colao A; Prete SD; Tagliaferri P; Tassone P; Budillon A; Venuta S; Abbruzzese A
    Oncogene; 2004 Sep; 23(41):6900-13. PubMed ID: 15286715
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Farnesyl transferase inhibitor R115777 induces apoptosis of human myeloma cells.
    Le Gouill S; Pellat-Deceunynck C; Harousseau JL; Rapp MJ; Robillard N; Bataille R; Amiot M
    Leukemia; 2002 Sep; 16(9):1664-7. PubMed ID: 12200678
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The farnesyltransferase inhibitor R115777 (ZARNESTRA) enhances the pro-apoptotic activity of interferon-alpha through the inhibition of multiple survival pathways.
    Caraglia M; Marra M; Viscomi C; D'Alessandro AM; Budillon A; Meo G; Arra C; Barbieri A; Rapp UR; Baldi A; Tassone P; Venuta S; Abbruzzese A; Tagliaferri P
    Int J Cancer; 2007 Nov; 121(10):2317-30. PubMed ID: 17657738
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of the antitumor effects of the selective farnesyl protein transferase inhibitor R115777 in vivo and in vitro.
    End DW; Smets G; Todd AV; Applegate TL; Fuery CJ; Angibaud P; Venet M; Sanz G; Poignet H; Skrzat S; Devine A; Wouters W; Bowden C
    Cancer Res; 2001 Jan; 61(1):131-7. PubMed ID: 11196150
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bovine serum amine oxidase and spm potentiate docetaxel and interferon-alpha effects in inducing apoptosis on human cancer cells through the generation of oxidative stress.
    Marra M; Lombardi A; Agostinelli E; Giuberti G; Zappavigna S; Tempera G; Vitale G; Bifulco M; Abbruzzese A; Caraglia M
    Biochim Biophys Acta; 2008 Dec; 1783(12):2269-78. PubMed ID: 18848847
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pharmacological inhibition of HSP90 and ras activity as a new strategy in the treatment of HNSCC.
    Misso G; Giuberti G; Lombardi A; Grimaldi A; Ricciardiello F; Giordano A; Tagliaferri P; Abbruzzese A; Caraglia M
    J Cell Physiol; 2013 Jan; 228(1):130-41. PubMed ID: 22566192
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of statins and farnesyl transferase inhibitors on ERK phosphorylation, apoptosis and cell viability in non-small lung cancer cells.
    Pelaia G; Gallelli L; Renda T; Fratto D; Falcone D; Caraglia M; Busceti MT; Terracciano R; Vatrella A; Maselli R; Savino R
    Cell Prolif; 2012 Dec; 45(6):557-65. PubMed ID: 23045963
    [TBL] [Abstract][Full Text] [Related]  

  • 9. R115777 (Zarnestra)/Zoledronic acid (Zometa) cooperation on inhibition of prostate cancer proliferation is paralleled by Erk/Akt inactivation and reduced Bcl-2 and bad phosphorylation.
    Caraglia M; Marra M; Leonetti C; Meo G; D'Alessandro AM; Baldi A; Santini D; Tonini G; Bertieri R; Zupi G; Budillon A; Abbruzzese A
    J Cell Physiol; 2007 May; 211(2):533-43. PubMed ID: 17192846
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Growth inhibition of astrocytoma cells by farnesyl transferase inhibitors is mediated by a combination of anti-proliferative, pro-apoptotic and anti-angiogenic effects.
    Feldkamp MM; Lau N; Guha A
    Oncogene; 1999 Dec; 18(52):7514-26. PubMed ID: 10602510
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Resveratrol induces cell cycle arrest and apoptosis with docetaxel in prostate cancer cells via a p53/ p21WAF1/CIP1 and p27KIP1 pathway.
    Singh SK; Banerjee S; Acosta EP; Lillard JW; Singh R
    Oncotarget; 2017 Mar; 8(10):17216-17228. PubMed ID: 28212547
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Preclinical antitumor activity and pharmacodynamic studies with the farnesyl protein transferase inhibitor R115777 in human breast cancer.
    Kelland LR; Smith V; Valenti M; Patterson L; Clarke PA; Detre S; End D; Howes AJ; Dowsett M; Workman P; Johnston SR
    Clin Cancer Res; 2001 Nov; 7(11):3544-50. PubMed ID: 11705875
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Farnesyltransferase inhibitor R115777 inhibits cell growth and induces apoptosis in mantle cell lymphoma.
    Rolland D; Camara-Clayette V; Barbarat A; Salles G; Coiffier B; Ribrag V; Thieblemont C
    Cancer Chemother Pharmacol; 2008 Apr; 61(5):855-63. PubMed ID: 17639395
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of farnesyl transferase inhibitor R115777 on the growth of fresh and cloned myeloma cells in vitro.
    Ochiai N; Uchida R; Fuchida S; Okano A; Okamoto M; Ashihara E; Inaba T; Fujita N; Matsubara H; Shimazaki C
    Blood; 2003 Nov; 102(9):3349-53. PubMed ID: 12842991
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of a R115777-resistant human multiple myeloma cell line with cross-resistance to PS-341.
    Buzzeo R; Enkemann S; Nimmanapalli R; Alsina M; Lichtenheld MG; Dalton WS; Beaupre DM
    Clin Cancer Res; 2005 Aug; 11(16):6057-64. PubMed ID: 16115951
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cells.
    Zhu K; Gerbino E; Beaupre DM; Mackley PA; Muro-Cacho C; Beam C; Hamilton AD; Lichtenheld MG; Kerr WG; Dalton W; Alsina M; Sebti SM
    Blood; 2005 Jun; 105(12):4759-66. PubMed ID: 15728126
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Caveolin-1 Modulates Docetaxel-Induced Cell Death in Breast Cancer Cell Subtypes through Different Mechanisms.
    Kang J; Park JH; Lee HJ; Jo U; Park JK; Seo JH; Kim YH; Kim I; Park KH
    Cancer Res Treat; 2016 Apr; 48(2):715-26. PubMed ID: 26511813
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Low dose histone deacetylase inhibitor, LBH589, potentiates anticancer effect of docetaxel in epithelial ovarian cancer via PI3K/Akt pathway in vitro.
    Chao H; Wang L; Hao J; Ni J; Chang L; Graham PH; Kearsley JH; Li Y
    Cancer Lett; 2013 Feb; 329(1):17-26. PubMed ID: 22995071
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models.
    Lobell RB; Omer CA; Abrams MT; Bhimnathwala HG; Brucker MJ; Buser CA; Davide JP; deSolms SJ; Dinsmore CJ; Ellis-Hutchings MS; Kral AM; Liu D; Lumma WC; Machotka SV; Rands E; Williams TM; Graham SL; Hartman GD; Oliff AI; Heimbrook DC; Kohl NE
    Cancer Res; 2001 Dec; 61(24):8758-68. PubMed ID: 11751396
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The farnesyltransferase inhibitor R115777 up-regulates the expression of death receptor 5 and enhances TRAIL-induced apoptosis in human lung cancer cells.
    Qiu Y; Liu X; Zou W; Yue P; Lonial S; Khuri FR; Sun SY
    Cancer Res; 2007 May; 67(10):4973-80. PubMed ID: 17510428
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.