These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

280 related articles for article (PubMed ID: 15970668)

  • 1. Chronic imatinib mesylate exposure leads to reduced intracellular drug accumulation by induction of the ABCG2 (BCRP) and ABCB1 (MDR1) drug transport pumps.
    Burger H; van Tol H; Brok M; Wiemer EA; de Bruijn EA; Guetens G; de Boeck G; Sparreboom A; Verweij J; Nooter K
    Cancer Biol Ther; 2005 Jul; 4(7):747-52. PubMed ID: 15970668
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Multidrug resistance proteins in gastrointestinal stromal tumors: site-dependent expression and initial response to imatinib.
    Théou N; Gil S; Devocelle A; Julié C; Lavergne-Slove A; Beauchet A; Callard P; Farinotti R; Le Cesne A; Lemoine A; Faivre-Bonhomme L; Emile JF
    Clin Cancer Res; 2005 Nov; 11(21):7593-8. PubMed ID: 16278376
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacokinetic resistance to imatinib mesylate: role of the ABC drug pumps ABCG2 (BCRP) and ABCB1 (MDR1) in the oral bioavailability of imatinib.
    Burger H; Nooter K
    Cell Cycle; 2004 Dec; 3(12):1502-5. PubMed ID: 15611623
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expression of the drug transporters MDR1/ABCB1, MRP1/ABCC1, MRP2/ABCC2, BCRP/ABCG2, and PXR in peripheral blood mononuclear cells and their relationship with the expression in intestine and liver.
    Albermann N; Schmitz-Winnenthal FH; Z'graggen K; Volk C; Hoffmann MM; Haefeli WE; Weiss J
    Biochem Pharmacol; 2005 Sep; 70(6):949-58. PubMed ID: 16054595
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sunitinib (Sutent, SU11248), a small-molecule receptor tyrosine kinase inhibitor, blocks function of the ATP-binding cassette (ABC) transporters P-glycoprotein (ABCB1) and ABCG2.
    Shukla S; Robey RW; Bates SE; Ambudkar SV
    Drug Metab Dispos; 2009 Feb; 37(2):359-65. PubMed ID: 18971320
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Resistance to daunorubicin, imatinib, or nilotinib depends on expression levels of ABCB1 and ABCG2 in human leukemia cells.
    Kosztyu P; Bukvova R; Dolezel P; Mlejnek P
    Chem Biol Interact; 2014 Aug; 219():203-10. PubMed ID: 24954033
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Degree of kinase inhibition achieved in vitro by imatinib and nilotinib is decreased by high levels of ABCB1 but not ABCG2.
    Eadie LN; Saunders VA; Hughes TP; White DL
    Leuk Lymphoma; 2013 Mar; 54(3):569-78. PubMed ID: 22845311
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Comparison of ATP-binding cassette transporter interactions with the tyrosine kinase inhibitors imatinib, nilotinib, and dasatinib.
    Dohse M; Scharenberg C; Shukla S; Robey RW; Volkmann T; Deeken JF; Brendel C; Ambudkar SV; Neubauer A; Bates SE
    Drug Metab Dispos; 2010 Aug; 38(8):1371-80. PubMed ID: 20423956
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Development of imatinib and dasatinib resistance: dynamics of expression of drug transporters ABCB1, ABCC1, ABCG2, MVP, and SLC22A1.
    Gromicho M; Dinis J; Magalhães M; Fernandes AR; Tavares P; Laires A; Rueff J; Rodrigues AS
    Leuk Lymphoma; 2011 Oct; 52(10):1980-90. PubMed ID: 21663515
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump.
    Burger H; van Tol H; Boersma AW; Brok M; Wiemer EA; Stoter G; Nooter K
    Blood; 2004 Nov; 104(9):2940-2. PubMed ID: 15251980
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tyrosine kinase inhibitors influence ABCG2 expression in EGFR-positive MDCK BCRP cells via the PI3K/Akt signaling pathway.
    Pick A; Wiese M
    ChemMedChem; 2012 Apr; 7(4):650-62. PubMed ID: 22354538
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Imatinib mesylate is a potent inhibitor of the ABCG2 (BCRP) transporter and reverses resistance to topotecan and SN-38 in vitro.
    Houghton PJ; Germain GS; Harwood FC; Schuetz JD; Stewart CF; Buchdunger E; Traxler P
    Cancer Res; 2004 Apr; 64(7):2333-7. PubMed ID: 15059881
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Influence of the dual ABCB1 and ABCG2 inhibitor tariquidar on the disposition of oral imatinib in mice.
    Gardner ER; Smith NF; Figg WD; Sparreboom A
    J Exp Clin Cancer Res; 2009 Jul; 28(1):99. PubMed ID: 19591692
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MicroRNA profiling in K-562 cells under imatinib treatment: influence of miR-212 and miR-328 on ABCG2 expression.
    Turrini E; Haenisch S; Laechelt S; Diewock T; Bruhn O; Cascorbi I
    Pharmacogenet Genomics; 2012 Mar; 22(3):198-205. PubMed ID: 22241070
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression and promoter methylation analysis of ATP-binding cassette genes in pancreatic cancer.
    Chen M; Xue X; Wang F; An Y; Tang D; Xu Y; Wang H; Yuan Z; Gao W; Wei J; Zhang J; Miao Y
    Oncol Rep; 2012 Jan; 27(1):265-9. PubMed ID: 21956451
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nilotinib concentration in cell lines and primary CD34(+) chronic myeloid leukemia cells is not mediated by active uptake or efflux by major drug transporters.
    Davies A; Jordanides NE; Giannoudis A; Lucas CM; Hatziieremia S; Harris RJ; Jørgensen HG; Holyoake TL; Pirmohamed M; Clark RE; Mountford JC
    Leukemia; 2009 Nov; 23(11):1999-2006. PubMed ID: 19710702
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A comprehensive study of polymorphisms in the ABCB1, ABCC2, ABCG2, NR1I2 genes and lymphoma risk.
    Campa D; Butterbach K; Slager SL; Skibola CF; de Sanjosé S; Benavente Y; Becker N; Foretova L; Maynadie M; Cocco P; Staines A; Kaaks R; Boffetta P; Brennan P; Conde L; Bracci PM; Caporaso NE; Strom SS; Camp NJ; Cerhan JR; ; Canzian F; Nieters A
    Int J Cancer; 2012 Aug; 131(4):803-12. PubMed ID: 21918980
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Instability of mRNA expression signatures of drug transporters in chronic myeloid leukemia patients resistant to imatinib.
    Gromicho M; Magalhães M; Torres F; Dinis J; Fernandes AR; Rendeiro P; Tavares P; Laires A; Rueff J; Sebastião Rodrigues A
    Oncol Rep; 2013 Feb; 29(2):741-50. PubMed ID: 23229016
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A new intestinal cell culture model to discriminate the relative contribution of P-gp and BCRP on transport of substrates such as imatinib.
    Graber-Maier A; Gutmann H; Drewe J
    Mol Pharm; 2010 Oct; 7(5):1618-28. PubMed ID: 20701289
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Association of genotypes and haplotypes of multi-drug transporter genes ABCB1 and ABCG2 with clinical response to imatinib mesylate in chronic myeloid leukemia patients.
    Au A; Aziz Baba A; Goh AS; Wahid Fadilah SA; Teh A; Rosline H; Ankathil R
    Biomed Pharmacother; 2014 Apr; 68(3):343-9. PubMed ID: 24581936
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.