171 related articles for article (PubMed ID: 15970798)
1. Theophylline pharmacokinetics: comparison of Cyp1a1(-/-) and Cyp1a2(-/-) knockout mice, humanized hCYP1A1_1A2 knock-in mice lacking either the mouse Cyp1a1 or Cyp1a2 gene, and Cyp1(+/+) wild-type mice.
Derkenne S; Curran CP; Shertzer HG; Dalton TP; Dragin N; Nebert DW
Pharmacogenet Genomics; 2005 Jul; 15(7):503-11. PubMed ID: 15970798
[TBL] [Abstract][Full Text] [Related]
2. For dioxin-induced birth defects, mouse or human CYP1A2 in maternal liver protects whereas mouse CYP1A1 and CYP1B1 are inconsequential.
Dragin N; Dalton TP; Miller ML; Shertzer HG; Nebert DW
J Biol Chem; 2006 Jul; 281(27):18591-600. PubMed ID: 16636061
[TBL] [Abstract][Full Text] [Related]
3. Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract.
Uno S; Dragin N; Miller ML; Dalton TP; Gonzalez FJ; Nebert DW
Free Radic Biol Med; 2008 Feb; 44(4):570-83. PubMed ID: 17997381
[TBL] [Abstract][Full Text] [Related]
4. Disruption of the gene for CYP1A2, which is expressed primarily in liver, leads to differential regulation of hepatic and pulmonary mouse CYP1A1 expression and augmented human CYP1A1 transcriptional activation in response to 3-methylcholanthrene in vivo.
Jiang W; Wang L; Kondraganti SR; Fazili IS; Couroucli XI; Felix EA; Moorthy B
J Pharmacol Exp Ther; 2010 Nov; 335(2):369-79. PubMed ID: 20732958
[TBL] [Abstract][Full Text] [Related]
5. Generation of a 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-)_Ahrd mouse line harboring the poor-affinity aryl hydrocarbon receptor.
Shi Z; Chen Y; Dong H; Amos-Kroohs RM; Nebert DW
Biochem Biophys Res Commun; 2008 Nov; 376(4):775-80. PubMed ID: 18814841
[TBL] [Abstract][Full Text] [Related]
6. Generation of 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-) mouse line.
Dragin N; Uno S; Wang B; Dalton TP; Nebert DW
Biochem Biophys Res Commun; 2007 Aug; 359(3):635-42. PubMed ID: 17560947
[TBL] [Abstract][Full Text] [Related]
7. Effect of subchronic 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on immune system and target gene responses in mice: calculation of benchmark doses for CYP1A1 and CYP1A2 related enzyme activities.
Vogel C; Donat S; Döhr O; Kremer J; Esser C; Roller M; Abel J
Arch Toxicol; 1997; 71(6):372-82. PubMed ID: 9195019
[TBL] [Abstract][Full Text] [Related]
8. Bioactivation versus detoxication of the urothelial carcinogen aristolochic acid I by human cytochrome P450 1A1 and 1A2.
Stiborová M; Levová K; Bárta F; Shi Z; Frei E; Schmeiser HH; Nebert DW; Phillips DH; Arlt VM
Toxicol Sci; 2012 Feb; 125(2):345-58. PubMed ID: 22086975
[TBL] [Abstract][Full Text] [Related]
9. Transcriptional activation of avian CYP1A4 and CYP1A5 by 2,3,7, 8-tetrachlorodibenzo-p-dioxin: differences in gene expression and regulation compared to mammalian CYP1A1 and CYP1A2.
Mahajan SS; Rifkind AB
Toxicol Appl Pharmacol; 1999 Feb; 155(1):96-106. PubMed ID: 10036222
[TBL] [Abstract][Full Text] [Related]
10. Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice.
Kapelyukh Y; Henderson CJ; Scheer N; Rode A; Wolf CR
Drug Metab Dispos; 2019 Aug; 47(8):907-918. PubMed ID: 31147315
[TBL] [Abstract][Full Text] [Related]
11. Aryl hydrocarbon receptor ligand 2,3,7,8-tetrachlorodibenzo-p-dioxin enhances liver damage in bile duct-ligated mice.
Ozeki J; Uno S; Ogura M; Choi M; Maeda T; Sakurai K; Matsuo S; Amano S; Nebert DW; Makishima M
Toxicology; 2011 Feb; 280(1-2):10-7. PubMed ID: 21095216
[TBL] [Abstract][Full Text] [Related]
12. The effect of dose on 2,3,7,8-TCDD tissue distribution, metabolism and elimination in CYP1A2 (-/-) knockout and C57BL/6N parental strains of mice.
Hakk H; Diliberto JJ; Birnbaum LS
Toxicol Appl Pharmacol; 2009 Nov; 241(1):119-26. PubMed ID: 19695277
[TBL] [Abstract][Full Text] [Related]
13. Lack of effect of aciclovir on metabolism of theophylline and expression of hepatic cytochrome P450 1A2 in rats.
Nadai M; Kato M; Yasui K; Kimura M; Zhao YL; Ueyama J; Tsunekawa Y; Yoshizumi H; Hasegawa T
Biol Pharm Bull; 2007 Mar; 30(3):562-8. PubMed ID: 17329857
[TBL] [Abstract][Full Text] [Related]
14. Severe 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) intoxication: insights into the measurement of hepatic cytochrome P450 1A2 induction.
Abraham K; Geusau A; Tosun Y; Helge H; Bauer S; Brockmöller J
Clin Pharmacol Ther; 2002 Aug; 72(2):163-74. PubMed ID: 12189363
[TBL] [Abstract][Full Text] [Related]
15. Characterization of the dose-response of CYP1B1, CYP1A1, and CYP1A2 in the liver of female Sprague-Dawley rats following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Walker NJ; Portier CJ; Lax SF; Crofts FG; Li Y; Lucier GW; Sutter TR
Toxicol Appl Pharmacol; 1999 Feb; 154(3):279-86. PubMed ID: 9931287
[TBL] [Abstract][Full Text] [Related]
16. Effects of histone deacetylation and DNA methylation on the constitutive and TCDD-inducible expressions of the human CYP1 family in MCF-7 and HeLa cells.
Nakajima M; Iwanari M; Yokoi T
Toxicol Lett; 2003 Sep; 144(2):247-56. PubMed ID: 12927368
[TBL] [Abstract][Full Text] [Related]
17. Modulation of cytochrome P450 1 (Cyp1) by vanadium in hepatic tissue and isolated hepatocyte of C57BL/6 mice.
Abdelhamid G; Amara IE; Anwar-Mohamed A; El-Kadi AO
Arch Toxicol; 2013 Aug; 87(8):1531-43. PubMed ID: 23423713
[TBL] [Abstract][Full Text] [Related]
18. 7H-dibenzo[c,g]carbazole metabolism by the mouse and human CYP1 family of enzymes.
Shertzer HG; Genter MB; Talaska G; Curran CP; Nebert DW; Dalton TP
Carcinogenesis; 2007 Jun; 28(6):1371-8. PubMed ID: 17166882
[TBL] [Abstract][Full Text] [Related]
19. Mitochondrial reactive oxygen production is dependent on the aromatic hydrocarbon receptor.
Senft AP; Dalton TP; Nebert DW; Genter MB; Puga A; Hutchinson RJ; Kerzee JK; Uno S; Shertzer HG
Free Radic Biol Med; 2002 Nov; 33(9):1268-78. PubMed ID: 12398935
[TBL] [Abstract][Full Text] [Related]
20. Phenotype of the Cyp1a1/1a2/1b1-/- triple-knockout mouse.
Dragin N; Shi Z; Madan R; Karp CL; Sartor MA; Chen C; Gonzalez FJ; Nebert DW
Mol Pharmacol; 2008 Jun; 73(6):1844-56. PubMed ID: 18372398
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
