These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
122 related articles for article (PubMed ID: 15974996)
1. Design and synthesis of protein superfamily-targeted chemical libraries for lead identification and optimization. Shuttleworth SJ; Connors RV; Fu J; Liu J; Lizarzaburu ME; Qiu W; Sharma R; Wãnska M; Zhang AJ Curr Med Chem; 2005; 12(11):1239-81. PubMed ID: 15974996 [TBL] [Abstract][Full Text] [Related]
2. Current status of virtual screening as analysed by target class. Stoermer MJ Med Chem; 2006 Jan; 2(1):89-112. PubMed ID: 16787359 [TBL] [Abstract][Full Text] [Related]
3. [Application of fluorescence polarization-based assay in high throughput screening]. Zhang TT; Du GH Yao Xue Xue Bao; 2005 Apr; 40(4):289-93. PubMed ID: 16011253 [No Abstract] [Full Text] [Related]
4. Conference report: inaugural Target Discovery World Congress 2009. Chaguturu R Future Med Chem; 2009 Oct; 1(7):1211-4. PubMed ID: 21426098 [TBL] [Abstract][Full Text] [Related]
5. Cell signalling: making connections. Gershon D Nature; 2004 Nov; 432(7014):243-9. PubMed ID: 15538373 [No Abstract] [Full Text] [Related]
6. Evaluation of virtual screening as a tool for chemical genetic applications. Campagna-Slater V; Schapira M J Chem Inf Model; 2009 Sep; 49(9):2082-91. PubMed ID: 19702241 [TBL] [Abstract][Full Text] [Related]
7. Allosteric targeting of receptor tyrosine kinases. De Smet F; Christopoulos A; Carmeliet P Nat Biotechnol; 2014 Nov; 32(11):1113-20. PubMed ID: 25380447 [TBL] [Abstract][Full Text] [Related]
8. Allosteric modulation of kinases and GPCRs: design principles and structural diversity. Lewis JA; Lebois EP; Lindsley CW Curr Opin Chem Biol; 2008 Jun; 12(3):269-80. PubMed ID: 18342020 [TBL] [Abstract][Full Text] [Related]
9. Discovery of enzyme inhibitors through combinatorial chemistry. Dolle RE Mol Divers; 1997; 2(4):223-36. PubMed ID: 9249758 [TBL] [Abstract][Full Text] [Related]
11. Indole RSK inhibitors. Part 2: optimization of cell potency and kinase selectivity. Kirrane TM; Boyer SJ; Burke J; Guo X; Snow RJ; Soleymanzadeh L; Swinamer A; Zhang Y; Madwed JB; Kashem M; Kugler S; O'Neill MM Bioorg Med Chem Lett; 2012 Jan; 22(1):738-42. PubMed ID: 22056746 [TBL] [Abstract][Full Text] [Related]
12. Polymer-supported synthesis of pyridone-focused libraries as inhibitors of anaplastic lymphoma kinase. Zhu T; Yan Z; Chucholowski A; Webb TR; Li R J Comb Chem; 2006; 8(3):401-9. PubMed ID: 16677010 [TBL] [Abstract][Full Text] [Related]
13. Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands. Festa C; Renga B; D'Amore C; Sepe V; Finamore C; De Marino S; Carino A; Cipriani S; Monti MC; Zampella A; Fiorucci S J Med Chem; 2014 Oct; 57(20):8477-95. PubMed ID: 25247751 [TBL] [Abstract][Full Text] [Related]
14. Strategies for the Discovery of Target-Specific or Isoform-Selective Modulators. Zhan P; Itoh Y; Suzuki T; Liu X J Med Chem; 2015 Oct; 58(19):7611-33. PubMed ID: 26086931 [TBL] [Abstract][Full Text] [Related]
15. Synthesis and biological evaluation of 3-ethylidene-1,3-dihydro-indol-2-ones as novel checkpoint 1 inhibitors. Lin NH; Xia P; Kovar P; Park C; Chen Z; Zhang H; Rosenberg SH; Sham HL Bioorg Med Chem Lett; 2006 Jan; 16(2):421-6. PubMed ID: 16242328 [TBL] [Abstract][Full Text] [Related]
16. In silico fragment screening by replica generation (FSRG) method for fragment-based drug design. Fukunishi Y; Mashimo T; Orita M; Ohno K; Nakamura H J Chem Inf Model; 2009 Apr; 49(4):925-33. PubMed ID: 19354203 [TBL] [Abstract][Full Text] [Related]
17. Use of parallel-synthesis combinatorial libraries for rapid identification of potent FKBP12 inhibitors. Choi C; Li JH; Vaal M; Thomas C; Limburg D; Wu YQ; Chen Y; Soni R; Scott C; Ross DT; Guo H; Howorth P; Valentine H; Liang S; Spicer D; Fuller M; Steiner J; Hamilton GS Bioorg Med Chem Lett; 2002 May; 12(10):1421-8. PubMed ID: 11992790 [TBL] [Abstract][Full Text] [Related]
18. The design and application of target-focused compound libraries. Harris CJ; Hill RD; Sheppard DW; Slater MJ; Stouten PF Comb Chem High Throughput Screen; 2011 Jul; 14(6):521-31. PubMed ID: 21521154 [TBL] [Abstract][Full Text] [Related]
19. The contribution of combinatorial chemistry to lead generation: an interim analysis. Adang AE; Hermkens PH Curr Med Chem; 2001 Jul; 8(9):985-98. PubMed ID: 11472238 [TBL] [Abstract][Full Text] [Related]
20. Optimization of three- and four-component reactions for polysubstituted piperidines: application to the synthesis and preliminary biological screening of a prototype library. Ulaczyk-Lesanko A; Pelletier E; Lee M; Prinz H; Waldmann H; Hall DG J Comb Chem; 2007; 9(4):695-703. PubMed ID: 17521171 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]