97 related articles for article (PubMed ID: 15977188)
1. Effect of silybin and its glycosides on the expression of cytochromes P450 1A2 and 3A4 in primary cultures of human hepatocytes.
Kosina P; Maurel P; Ulrichová J; Dvorák Z
J Biochem Mol Toxicol; 2005; 19(3):149-53. PubMed ID: 15977188
[TBL] [Abstract][Full Text] [Related]
2. Benzodiazepines medazepam and midazolam are activators of pregnane X receptor and weak inducers of CYP3A4: investigation in primary cultures of human hepatocytes and hepatocarcinoma cell lines.
Vrzal R; Kubesova K; Pavek P; Dvorak Z
Toxicol Lett; 2010 Mar; 193(2):183-8. PubMed ID: 20080160
[TBL] [Abstract][Full Text] [Related]
3. Microtubules-interfering agents restrict aryl hydrocarbon receptor-mediated CYP1A2 induction in primary cultures of human hepatocytes via c-jun-N-terminal kinase and glucocorticoid receptor.
Vrzal R; Daujat-Chavanieu M; Pascussi JM; Ulrichova J; Maurel P; Dvorak Z
Eur J Pharmacol; 2008 Mar; 581(3):244-54. PubMed ID: 18177856
[TBL] [Abstract][Full Text] [Related]
4. Regulation of CYP1A and CYP3A mRNAs by ascorbic acid in guinea pigs.
Mori T; Itoh S; Ohgiya S; Ishizaki K; Kamataki T
Arch Biochem Biophys; 1997 Dec; 348(2):268-77. PubMed ID: 9434738
[TBL] [Abstract][Full Text] [Related]
5. Effect of cell density and epidermal growth factor on the inducible expression of CYP3A and CYP1A genes in human hepatocytes in primary culture.
Greuet J; Pichard L; Ourlin JC; Bonfils C; Domergue J; Le Treut P; Maurel P
Hepatology; 1997 May; 25(5):1166-75. PubMed ID: 9141435
[TBL] [Abstract][Full Text] [Related]
6. Induction of CYP3A by 2,3-oxidosqualene:lanosterol cyclase inhibitors is mediated by an endogenous squalene metabolite in primary cultured rat hepatocytes.
Shenoy SD; Spencer TA; Mercer-Haines NA; Abdolalipour M; Wurster WL; Runge-Morris M; Kocarek TA
Mol Pharmacol; 2004 May; 65(5):1302-12. PubMed ID: 15102959
[TBL] [Abstract][Full Text] [Related]
7. Effects of dinuclear copper(II) complexes with 6-(benzylamino)purine derivatives on AhR and PXR dependent expression of cytochromes P450 CYP1A2 and CYP3A4 genes in primary cultures of human hepatocytes.
Dvorák Z; Vrzal R; Starha P; Klanicová A; Trávnícek Z
Toxicol In Vitro; 2010 Mar; 24(2):425-9. PubMed ID: 19854261
[TBL] [Abstract][Full Text] [Related]
8. Effect of colchicine and its derivatives on the expression of selected isoforms of cytochrome P450 in primary cultures of human hepatocytes.
Dvorák Z; Ulrichová J; Modrianský M; Maurel P
Acta Univ Palacki Olomuc Fac Med; 2000; 143():47-50. PubMed ID: 11144118
[TBL] [Abstract][Full Text] [Related]
9. Silybin inactivates cytochromes P450 3A4 and 2C9 and inhibits major hepatic glucuronosyltransferases.
Sridar C; Goosen TC; Kent UM; Williams JA; Hollenberg PF
Drug Metab Dispos; 2004 Jun; 32(6):587-94. PubMed ID: 15155549
[TBL] [Abstract][Full Text] [Related]
10. Examination of Zolpidem effects on AhR- and PXR-dependent expression of drug-metabolizing cytochromes P450 in primary cultures of human hepatocytes.
Bachleda P; Vrzal R; Pivnicka J; Cvek B; Dvorak Z
Toxicol Lett; 2009 Dec; 191(1):74-8. PubMed ID: 19686824
[TBL] [Abstract][Full Text] [Related]
11. Effect of interferon-α2b on the expression of various drug-metabolizing enzymes and transporters in co-cultures of freshly prepared human primary hepatocytes.
Chen C; Han YH; Yang Z; Rodrigues AD
Xenobiotica; 2011 Jun; 41(6):476-85. PubMed ID: 21381897
[TBL] [Abstract][Full Text] [Related]
12. Silybin is metabolized by cytochrome P450 2C8 in vitro.
Jancová P; Anzenbacherová E; Papousková B; Lemr K; Luzná P; Veinlichová A; Anzenbacher P; Simánek V
Drug Metab Dispos; 2007 Nov; 35(11):2035-9. PubMed ID: 17670841
[TBL] [Abstract][Full Text] [Related]
13. Effects of avasimibe on cytochrome P450 2C9 expression in vitro and in vivo.
Sahi J; Stern RH; Milad MA; Rose KA; Gibson G; Zheng X; Stilgenbauer L; Sadagopan N; Jolley S; Gilbert D; LeCluyse EL
Drug Metab Dispos; 2004 Dec; 32(12):1370-6. PubMed ID: 15333513
[TBL] [Abstract][Full Text] [Related]
14. Temporal kinetics and concentration-response relationships for induction of CYP1A, CYP2B, and CYP3A in primary cultures of beagle dog hepatocytes.
Graham RA; Tyler LO; Krol WL; Silver IS; Webster LO; Clark P; Chen L; Banks T; LeCluyse EL
J Biochem Mol Toxicol; 2006; 20(2):69-78. PubMed ID: 16615094
[TBL] [Abstract][Full Text] [Related]
15. An 'all-inclusive' 96-well cytochrome P450 induction method: measuring enzyme activity, mRNA levels, protein levels, and cytotoxicity from one well using cryopreserved human hepatocytes.
Halladay JS; Wong S; Khojasteh SC; Grepper S
J Pharmacol Toxicol Methods; 2012; 66(3):270-5. PubMed ID: 22809809
[TBL] [Abstract][Full Text] [Related]
16. Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells.
Westerink WM; Schoonen WG
Toxicol In Vitro; 2007 Dec; 21(8):1581-91. PubMed ID: 17637504
[TBL] [Abstract][Full Text] [Related]
17. Antioxidant properties of silybin glycosides.
Kosina P; Kren V; Gebhardt R; Grambal F; Ulrichová J; Walterová D
Phytother Res; 2002 Mar; 16 Suppl 1():S33-9. PubMed ID: 11933137
[TBL] [Abstract][Full Text] [Related]
18. Impact of transcription factor profile and chromatin conformation on human hepatocyte CYP3A gene expression.
Phillips A; Hood SR; Gibson GG; Plant NJ
Drug Metab Dispos; 2005 Feb; 33(2):233-42. PubMed ID: 15523048
[TBL] [Abstract][Full Text] [Related]
19. A multi-endpoint evaluation of cytochrome P450 1A2, 2B6 and 3A4 induction response in human hepatocyte cultures after treatment with β-naphthoflavone, phenobarbital and rifampicin.
Zhang JG; Ho T; Callendrello AL; Crespi CL; Stresser DM
Drug Metab Lett; 2010 Dec; 4(4):185-94. PubMed ID: 20583967
[TBL] [Abstract][Full Text] [Related]
20. Activation of MAPKs influences the expression of drug-metabolizing enzymes in primary human hepatocytes.
Bachleda P; Vrzal R; Dvorák Z
Gen Physiol Biophys; 2009 Sep; 28(3):316-20. PubMed ID: 20037198
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
