These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 15980104)

  • 1. Cyp2a6 is a principal enzyme involved in hydroxylation of 1,7-dimethylxanthine, a main caffeine metabolite, in humans.
    Kimura M; Yamazaki H; Fujieda M; Kiyotani K; Honda G; Saruwatari J; Nakagawa K; Ishizaki T; Kamataki T
    Drug Metab Dispos; 2005 Sep; 33(9):1361-6. PubMed ID: 15980104
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In vivo evaluation of CYP1A2, CYP2A6, NAT-2 and xanthine oxidase activities in a Greek population sample by the RP-HPLC monitoring of caffeine metabolic ratios.
    Begas E; Kouvaras E; Tsakalof A; Papakosta S; Asprodini EK
    Biomed Chromatogr; 2007 Feb; 21(2):190-200. PubMed ID: 17221922
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Contribution of CYP2C9, CYP2A6, and CYP2B6 to valproic acid metabolism in hepatic microsomes from individuals with the CYP2C9*1/*1 genotype.
    Kiang TK; Ho PC; Anari MR; Tong V; Abbott FS; Chang TK
    Toxicol Sci; 2006 Dec; 94(2):261-71. PubMed ID: 16945988
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Roles of cytochromes P450 1A2, 2A6, and 2C8 in 5-fluorouracil formation from tegafur, an anticancer prodrug, in human liver microsomes.
    Komatsu T; Yamazaki H; Shimada N; Nakajima M; Yokoi T
    Drug Metab Dispos; 2000 Dec; 28(12):1457-63. PubMed ID: 11095583
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Escherichia coli MTC, a human NADPH P450 reductase competent mutagenicity tester strain for the expression of human cytochrome P450 isoforms 1A1, 1A2, 2A6, 3A4, or 3A5: catalytic activities and mutagenicity studies.
    Kranendonk M; Carreira F; Theisen P; Laires A; Fisher CW; Rueff J; Estabrook RW; Vermeulen NP
    Mutat Res; 1999 Apr; 441(1):73-83. PubMed ID: 10224324
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vitro evaluation of valproic acid as an inhibitor of human cytochrome P450 isoforms: preferential inhibition of cytochrome P450 2C9 (CYP2C9).
    Wen X; Wang JS; Kivistö KT; Neuvonen PJ; Backman JT
    Br J Clin Pharmacol; 2001 Nov; 52(5):547-53. PubMed ID: 11736863
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of coumarin 7-hydroxylase activity in human liver microsomes.
    Draper AJ; Madan A; Parkinson A
    Arch Biochem Biophys; 1997 May; 341(1):47-61. PubMed ID: 9143352
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional characterization of single nucleotide polymorphisms with amino acid substitution in CYP1A2, CYP2A6, and CYP2B6 found in the Japanese population.
    Iwasaki M; Yoshimura Y; Asahi S; Saito K; Sakai S; Morita S; Takenaka O; Inoda T; Kashiyama E; Aoyama A; Nakabayashi T; Omori S; Kuwabara T; Izumi T; Nakamura K; Takanaka K; Nakayama Y; Takeuchi M; Nakamura H; Kametani S; Terauchi Y; Hashizume T; Nagayama S; Kume T; Achira M; Kawai H; Kawashiro T; Nakamura A; Nakai Y; Kagayama A; Shiraga T; Niwa T; Yoshimura T; Morita J; Ohsawa F; Tani M; Osawa N; Ida K; Noguchi K
    Drug Metab Pharmacokinet; 2004 Dec; 19(6):444-52. PubMed ID: 15681899
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vitro inhibition of cytochrome P450 enzymes in human liver microsomes by a potent CYP2A6 inhibitor, trans-2-phenylcyclopropylamine (tranylcypromine), and its nonamine analog, cyclopropylbenzene.
    Taavitsainen P; Juvonen R; Pelkonen O
    Drug Metab Dispos; 2001 Mar; 29(3):217-22. PubMed ID: 11181487
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evaluation of methoxsalen, tranylcypromine, and tryptamine as specific and selective CYP2A6 inhibitors in vitro.
    Zhang W; Kilicarslan T; Tyndale RF; Sellers EM
    Drug Metab Dispos; 2001 Jun; 29(6):897-902. PubMed ID: 11353760
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of human cytochrome P450 enzymes by the natural hepatotoxin safrole.
    Ueng YF; Hsieh CH; Don MJ
    Food Chem Toxicol; 2005 May; 43(5):707-12. PubMed ID: 15778010
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabolism of theophylline by cDNA-expressed human cytochromes P-450.
    Ha HR; Chen J; Freiburghaus AU; Follath F
    Br J Clin Pharmacol; 1995 Mar; 39(3):321-6. PubMed ID: 7619675
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Involvement of CYP2A6 in the formation of a novel metabolite, 3-hydroxypilocarpine, from pilocarpine in human liver microsomes.
    Endo T; Ban M; Hirata K; Yamamoto A; Hara Y; Momose Y
    Drug Metab Dispos; 2007 Mar; 35(3):476-83. PubMed ID: 17178767
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Simultaneous action of the flavonoid quercetin on cytochrome P450 (CYP) 1A2, CYP2A6, N-acetyltransferase and xanthine oxidase activity in healthy volunteers.
    Chen Y; Xiao P; Ou-Yang DS; Fan L; Guo D; Wang YN; Han Y; Tu JH; Zhou G; Huang YF; Zhou HH
    Clin Exp Pharmacol Physiol; 2009 Aug; 36(8):828-33. PubMed ID: 19215233
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of human CYP1A2 activity in vitro by methylxanthines: potent competitive inhibition by 8-phenyltheophylline.
    Murray S; Odupitan AO; Murray BP; Boobis AR; Edwards RJ
    Xenobiotica; 2001 Mar; 31(3):135-51. PubMed ID: 11465391
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of human cytochrome P450 (CYP) in the metabolic activation of nitrosamine derivatives: application of genetically engineered Salmonella expressing human CYP.
    Kamataki T; Fujita K; Nakayama K; Yamazaki Y; Miyamoto M; Ariyoshi N
    Drug Metab Rev; 2002 Aug; 34(3):667-76. PubMed ID: 12214673
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Metabolism of 7-ethoxycoumarin, safrole, flavanone and hydroxyflavanone by cytochrome P450 2A6 variants.
    Uno T; Obe Y; Ogura C; Goto T; Yamamoto K; Nakamura M; Kanamaru K; Yamagata H; Imaishi H
    Biopharm Drug Dispos; 2013 Mar; 34(2):87-97. PubMed ID: 23112005
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Determination of the activity of cytochrome P-450 CYP2A6 by HPLC method with caffeine as metabolizing probe].
    Li J; Peng XQ; Zhang J; Xu JP
    Yao Xue Xue Bao; 2006 Mar; 41(3):282-4. PubMed ID: 16759004
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparison of CYP2A6 catalytic activity on coumarin 7-hydroxylation in human and monkey liver microsomes.
    Li Y; Li NY; Sellers EM
    Eur J Drug Metab Pharmacokinet; 1997; 22(4):295-304. PubMed ID: 9512924
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Induction of liver microsomal cytochrome P450 in cynomolgus monkeys.
    Bullock P; Pearce R; Draper A; Podval J; Bracken W; Veltman J; Thomas P; Parkinson A
    Drug Metab Dispos; 1995 Jul; 23(7):736-48. PubMed ID: 7587963
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.