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4. The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation. Wong YC; Holzbaur EL J Neurosci; 2014 Jan; 34(4):1293-305. PubMed ID: 24453320 [TBL] [Abstract][Full Text] [Related]
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8. Protein turnover and inclusion body formation. Mitra S; Tsvetkov AS; Finkbeiner S Autophagy; 2009 Oct; 5(7):1037-8. PubMed ID: 19838079 [TBL] [Abstract][Full Text] [Related]
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10. Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein. Sarkar S; Davies JE; Huang Z; Tunnacliffe A; Rubinsztein DC J Biol Chem; 2007 Feb; 282(8):5641-52. PubMed ID: 17182613 [TBL] [Abstract][Full Text] [Related]
11. Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease. Wyttenbach A; Swartz J; Kita H; Thykjaer T; Carmichael J; Bradley J; Brown R; Maxwell M; Schapira A; Orntoft TF; Kato K; Rubinsztein DC Hum Mol Genet; 2001 Aug; 10(17):1829-45. PubMed ID: 11532992 [TBL] [Abstract][Full Text] [Related]
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14. The regulation of N-terminal Huntingtin (Htt552) accumulation by Beclin1. Wu JC; Qi L; Wang Y; Kegel KB; Yoder J; Difiglia M; Qin ZH; Lin F Acta Pharmacol Sin; 2012 Jun; 33(6):743-51. PubMed ID: 22543707 [TBL] [Abstract][Full Text] [Related]
15. Role of autophagy in the clearance of mutant huntingtin: a step towards therapy? Ravikumar B; Rubinsztein DC Mol Aspects Med; 2006; 27(5-6):520-7. PubMed ID: 16973207 [TBL] [Abstract][Full Text] [Related]
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17. Impaired ubiquitin-proteasome system activity in the synapses of Huntington's disease mice. Wang J; Wang CE; Orr A; Tydlacka S; Li SH; Li XJ J Cell Biol; 2008 Mar; 180(6):1177-89. PubMed ID: 18362179 [TBL] [Abstract][Full Text] [Related]
18. Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy. Ravikumar B; Duden R; Rubinsztein DC Hum Mol Genet; 2002 May; 11(9):1107-17. PubMed ID: 11978769 [TBL] [Abstract][Full Text] [Related]
19. Temporal separation of aggregation and ubiquitination during early inclusion formation in transgenic mice carrying the Huntington's disease mutation. Gong B; Kielar C; Morton AJ PLoS One; 2012; 7(7):e41450. PubMed ID: 22848498 [TBL] [Abstract][Full Text] [Related]
20. 14-3-3zeta is indispensable for aggregate formation of polyglutamine-expanded huntingtin protein. Omi K; Hachiya NS; Tanaka M; Tokunaga K; Kaneko K Neurosci Lett; 2008 Jan; 431(1):45-50. PubMed ID: 18078716 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]